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    STX16 syntaxin 16 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 694811, updated on 9-Nov-2023

    Summary

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    Gene symbol
    STX16
    Gene description
    syntaxin 16
    See related
    Ensembl:ENSMMUG00000001833 Ensembl:ENSMMUG00000010006
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Also known as
    NPEPL1
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    Genomic context

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    See STX16 in Genome Data Viewer
    Location:
    chromosome: 10
    Exon count:
    24
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 10 NC_041763.1 (93810793..93873443)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 10 NC_027902.1 (5691825..5757503, complement)

    Chromosome 10 - NC_041763.1Genomic Context describing neighboring genes Neighboring gene APC down-regulated 1 like Neighboring gene putative 60S ribosomal protein L37a Neighboring gene uncharacterized LOC114670515 Neighboring gene uncharacterized LOC114670516 Neighboring gene microRNA mir-296 Neighboring gene microRNA mir-298

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables SNAP receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables SNARE binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables manganese ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables metalloaminopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in intracellular protein transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in vesicle docking IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in vesicle fusion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in vesicle-mediated transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of SNARE complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in endomembrane system IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    syntaxin-16
    Names
    putative aminopeptidase NPEPL1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001257651.1 → NP_001244580.1  syntaxin-16

      See identical proteins and their annotated locations for NP_001244580.1

      Status: PROVISIONAL

      Source sequence(s)
      JU321305
      UniProtKB/TrEMBL
      H9ERQ2
      Related
      ENSMMUP00000002440.4, ENSMMUT00000002583.4
      Conserved Domains (2) summary
      COG5325
      Location:56 → 284
      COG5325; t-SNARE complex subunit, syntaxin [Intracellular trafficking and secretion]
      cd15845
      Location:216 → 274
      SNARE_syntaxin16; SNARE motif of syntaxin 16

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041763.1 Reference Mmul_10 Primary Assembly

      Range
      93810793..93873443
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015148683.2 → XP_015004169.1  syntaxin-16 isoform X11

      UniProtKB/TrEMBL
      H9YUI6
      Related
      ENSMMUP00000002438.4, ENSMMUT00000002581.4
      Conserved Domains (2) summary
      COG5325
      Location:52 → 280
      COG5325; t-SNARE complex subunit, syntaxin [Intracellular trafficking and secretion]
      cd15845
      Location:212 → 270
      SNARE_syntaxin16; SNARE motif of syntaxin 16

    2. XM_015148666.2 → XP_015004152.1  syntaxin-16 isoform X2

      Conserved Domains (4) summary
      cd00433
      Location:372 → 789
      Peptidase_M17; Cytosol aminopeptidase family, N-terminal and catalytic domains. Family M17 contains zinc- and manganese-dependent exopeptidases ( EC 3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and ...
      cd15845
      Location:229 → 287
      SNARE_syntaxin16; SNARE motif of syntaxin 16
      pfam00804
      Location:78 → 261
      Syntaxin; Syntaxin
      cl00143
      Location:78 → 184
      SynN; Syntaxin N-terminus domain; syntaxins are nervous system-specific proteins implicated in the docking of synaptic vesicles with the presynaptic plasma membrane; they are a family of receptors for intracellular transport vesicles; each target membrane may ...

    3. XM_015148682.2 → XP_015004168.1  syntaxin-16 isoform X10

      UniProtKB/TrEMBL
      F7GS44, H9YUI7
      Conserved Domains (2) summary
      COG5325
      Location:69 → 297
      COG5325; t-SNARE complex subunit, syntaxin [Intracellular trafficking and secretion]
      cd15845
      Location:229 → 287
      SNARE_syntaxin16; SNARE motif of syntaxin 16

    4. XM_015148668.2 → XP_015004154.1  syntaxin-16 isoform X4

      Conserved Domains (4) summary
      cd00433
      Location:355 → 772
      Peptidase_M17; Cytosol aminopeptidase family, N-terminal and catalytic domains. Family M17 contains zinc- and manganese-dependent exopeptidases ( EC 3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and ...
      cd15845
      Location:212 → 270
      SNARE_syntaxin16; SNARE motif of syntaxin 16
      pfam00804
      Location:61 → 244
      Syntaxin; Syntaxin
      cl00143
      Location:61 → 167
      SynN; Syntaxin N-terminus domain; syntaxins are nervous system-specific proteins implicated in the docking of synaptic vesicles with the presynaptic plasma membrane; they are a family of receptors for intracellular transport vesicles; each target membrane may ...

    5. XM_015148667.2 → XP_015004153.1  syntaxin-16 isoform X3

      Conserved Domains (4) summary
      cd00433
      Location:359 → 776
      Peptidase_M17; Cytosol aminopeptidase family, N-terminal and catalytic domains. Family M17 contains zinc- and manganese-dependent exopeptidases ( EC 3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and ...
      cd15845
      Location:216 → 274
      SNARE_syntaxin16; SNARE motif of syntaxin 16
      pfam00804
      Location:65 → 248
      Syntaxin; Syntaxin
      cl00143
      Location:65 → 171
      SynN; Syntaxin N-terminus domain; syntaxins are nervous system-specific proteins implicated in the docking of synaptic vesicles with the presynaptic plasma membrane; they are a family of receptors for intracellular transport vesicles; each target membrane may ...

    6. XM_015148665.2 → XP_015004151.1  syntaxin-16 isoform X1

      Conserved Domains (4) summary
      cd00433
      Location:376 → 793
      Peptidase_M17; Cytosol aminopeptidase family, N-terminal and catalytic domains. Family M17 contains zinc- and manganese-dependent exopeptidases ( EC 3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and ...
      cd15845
      Location:233 → 291
      SNARE_syntaxin16; SNARE motif of syntaxin 16
      pfam00804
      Location:82 → 265
      Syntaxin; Syntaxin
      cl00143
      Location:82 → 188
      SynN; Syntaxin N-terminus domain; syntaxins are nervous system-specific proteins implicated in the docking of synaptic vesicles with the presynaptic plasma membrane; they are a family of receptors for intracellular transport vesicles; each target membrane may ...

    7. XM_015148670.2 → XP_015004156.1  syntaxin-16 isoform X5

      Conserved Domains (3) summary
      COG5325
      Location:73 → 295
      COG5325; t-SNARE complex subunit, syntaxin [Intracellular trafficking and secretion]
      cd00433
      Location:376 → 809
      Peptidase_M17; Cytosol aminopeptidase family, N-terminal and catalytic domains. Family M17 contains zinc- and manganese-dependent exopeptidases ( EC 3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and ...
      cd15845
      Location:233 → 291
      SNARE_syntaxin16; SNARE motif of syntaxin 16

    8. XM_015148681.2 → XP_015004167.1  syntaxin-16 isoform X9

      UniProtKB/TrEMBL
      F7GS43, H9ER40
      Related
      ENSMMUP00000002439.3, ENSMMUT00000002582.4
      Conserved Domains (2) summary
      COG5325
      Location:73 → 301
      COG5325; t-SNARE complex subunit, syntaxin [Intracellular trafficking and secretion]
      cd15845
      Location:233 → 291
      SNARE_syntaxin16; SNARE motif of syntaxin 16

    9. XM_015148675.2 → XP_015004161.1  syntaxin-16 isoform X7

      Conserved Domains (2) summary
      cd00433
      Location:190 → 607
      Peptidase_M17; Cytosol aminopeptidase family, N-terminal and catalytic domains. Family M17 contains zinc- and manganese-dependent exopeptidases ( EC 3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and ...
      cd15845
      Location:47 → 105
      SNARE_syntaxin16; SNARE motif of syntaxin 16

    10. XM_028827168.1 → XP_028683001.1  syntaxin-16 isoform X7

      Conserved Domains (2) summary
      cd00433
      Location:190 → 607
      Peptidase_M17; Cytosol aminopeptidase family, N-terminal and catalytic domains. Family M17 contains zinc- and manganese-dependent exopeptidases ( EC 3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and ...
      cd15845
      Location:47 → 105
      SNARE_syntaxin16; SNARE motif of syntaxin 16

    11. XM_015148673.2 → XP_015004159.1  syntaxin-16 isoform X6

      Conserved Domains (4) summary
      cd00433
      Location:323 → 740
      Peptidase_M17; Cytosol aminopeptidase family, N-terminal and catalytic domains. Family M17 contains zinc- and manganese-dependent exopeptidases ( EC 3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and ...
      cd15845
      Location:180 → 238
      SNARE_syntaxin16; SNARE motif of syntaxin 16
      pfam00804
      Location:29 → 212
      Syntaxin; Syntaxin
      cl00143
      Location:29 → 135
      SynN; Syntaxin N-terminus domain; syntaxins are nervous system-specific proteins implicated in the docking of synaptic vesicles with the presynaptic plasma membrane; they are a family of receptors for intracellular transport vesicles; each target membrane may ...

    12. XM_015148674.2 → XP_015004160.1  syntaxin-16 isoform X7

      Conserved Domains (2) summary
      cd00433
      Location:190 → 607
      Peptidase_M17; Cytosol aminopeptidase family, N-terminal and catalytic domains. Family M17 contains zinc- and manganese-dependent exopeptidases ( EC 3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and ...
      cd15845
      Location:47 → 105
      SNARE_syntaxin16; SNARE motif of syntaxin 16

    13. XM_015148671.2 → XP_015004157.1  syntaxin-16 isoform X6

      Conserved Domains (4) summary
      cd00433
      Location:323 → 740
      Peptidase_M17; Cytosol aminopeptidase family, N-terminal and catalytic domains. Family M17 contains zinc- and manganese-dependent exopeptidases ( EC 3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and ...
      cd15845
      Location:180 → 238
      SNARE_syntaxin16; SNARE motif of syntaxin 16
      pfam00804
      Location:29 → 212
      Syntaxin; Syntaxin
      cl00143
      Location:29 → 135
      SynN; Syntaxin N-terminus domain; syntaxins are nervous system-specific proteins implicated in the docking of synaptic vesicles with the presynaptic plasma membrane; they are a family of receptors for intracellular transport vesicles; each target membrane may ...

    14. XM_015148672.2 → XP_015004158.1  syntaxin-16 isoform X6

      Conserved Domains (4) summary
      cd00433
      Location:323 → 740
      Peptidase_M17; Cytosol aminopeptidase family, N-terminal and catalytic domains. Family M17 contains zinc- and manganese-dependent exopeptidases ( EC 3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and ...
      cd15845
      Location:180 → 238
      SNARE_syntaxin16; SNARE motif of syntaxin 16
      pfam00804
      Location:29 → 212
      Syntaxin; Syntaxin
      cl00143
      Location:29 → 135
      SynN; Syntaxin N-terminus domain; syntaxins are nervous system-specific proteins implicated in the docking of synaptic vesicles with the presynaptic plasma membrane; they are a family of receptors for intracellular transport vesicles; each target membrane may ...

    15. XM_015148676.2 → XP_015004162.1  syntaxin-16 isoform X7

      Conserved Domains (2) summary
      cd00433
      Location:190 → 607
      Peptidase_M17; Cytosol aminopeptidase family, N-terminal and catalytic domains. Family M17 contains zinc- and manganese-dependent exopeptidases ( EC 3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and ...
      cd15845
      Location:47 → 105
      SNARE_syntaxin16; SNARE motif of syntaxin 16

    16. XM_015148677.2 → XP_015004163.1  syntaxin-16 isoform X7

      Conserved Domains (2) summary
      cd00433
      Location:190 → 607
      Peptidase_M17; Cytosol aminopeptidase family, N-terminal and catalytic domains. Family M17 contains zinc- and manganese-dependent exopeptidases ( EC 3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and ...
      cd15845
      Location:47 → 105
      SNARE_syntaxin16; SNARE motif of syntaxin 16

    17. XM_015148679.2 → XP_015004165.1  syntaxin-16 isoform X8

      UniProtKB/TrEMBL
      G7N4B5, H9EU73
      Related
      ENSMMUP00000059195.1, ENSMMUT00000068606.2
      Conserved Domains (1) summary
      cd00433
      Location:35 → 487
      Peptidase_M17; Cytosol aminopeptidase family, N-terminal and catalytic domains. Family M17 contains zinc- and manganese-dependent exopeptidases ( EC 3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and ...
    Nucleotide Protein
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