U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    CRHR1 corticotropin releasing hormone receptor 1 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 574095, updated on 17-Aug-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    CRHR1provided by VGNC
    Official Full Name
    corticotropin releasing hormone receptor 1provided by VGNC
    Primary source
    VGNC:VGNC:81184
    See related
    Ensembl:ENSMMUG00000004108
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Also known as
    CRF1
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See CRHR1 in Genome Data Viewer
    Location:
    chromosome: 16
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 16 NC_041769.1 (57581792..57638936)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 16 NC_027908.1 (52237376..52289036)

    Chromosome 16 - NC_041769.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC106994069 Neighboring gene uncharacterized LOC114673220 Neighboring gene uncharacterized LOC114673218 Neighboring gene signal peptide peptidase like 2C

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. CRHR1 genotypes, neural circuits and the diathesis for anxiety and depression. Rogers J, et al. Mol Psychiatry, 2013 Jun. PMID 23147386, Free PMC Article
    2. Monkey corticotropin-releasing factor1 receptor: Complementary DNA cloning and pharmacological characterization. Oshida Y, et al. Life Sci, 2004 Feb 27. PMID 14761672
    3. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    4. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    5. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables G protein-coupled peptide receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables corticotrophin-releasing factor receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables corticotropin-releasing hormone binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables corticotropin-releasing hormone receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in adenylate cyclase-activating G protein-coupled receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cell surface receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in neuron projection IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    corticotropin-releasing factor receptor 1
    Names
    CRF-R-1
    CRF-R1
    CRFR-1
    corticotropin releasing factor receptor type 1

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001032803.1 → NP_001027975.1  corticotropin-releasing factor receptor 1 precursor

      See identical proteins and their annotated locations for NP_001027975.1

      Status: PROVISIONAL

      Source sequence(s)
      AB078141
      UniProtKB/Swiss-Prot
      Q76LL8
      UniProtKB/TrEMBL
      F6Z590
      Related
      ENSMMUP00000045328.2, ENSMMUT00000067471.2
      Conserved Domains (2) summary
      smart00008
      Location:40 → 111
      HormR; Domain present in hormone receptors
      cd15445
      Location:116 → 380
      7tmB1_CRF-R1; corticotropin-releasing factor receptor 1, member of the class B family of seven-transmembrane G protein-coupled receptors

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041769.1 Reference Mmul_10 Primary Assembly

      Range
      57581792..57638936
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028835446.1 → XP_028691279.1  corticotropin-releasing factor receptor 1 isoform X6

      UniProtKB/TrEMBL
      A0A1D5R687, F6Z590
      Related
      ENSMMUP00000055825.1, ENSMMUT00000067106.2
      Conserved Domains (2) summary
      smart00008
      Location:40 → 111
      HormR; Domain present in hormone receptors
      cd15445
      Location:116 → 409
      7tmB1_CRF-R1; corticotropin-releasing factor receptor 1, member of the class B family of seven-transmembrane G protein-coupled receptors

    2. XM_015119719.2 → XP_014975205.1  corticotropin-releasing factor receptor 1 isoform X2

      Conserved Domains (2) summary
      smart00008
      Location:40 → 111
      HormR; Domain present in hormone receptors
      pfam00002
      Location:116 → 313
      7tm_2; 7 transmembrane receptor (Secretin family)

    3. XM_028835444.1 → XP_028691277.1  corticotropin-releasing factor receptor 1 isoform X3

      UniProtKB/TrEMBL
      F6Z517, F6Z590
      Related
      ENSMMUP00000005497.3, ENSMMUT00000005837.4
      Conserved Domains (2) summary
      cd15445
      Location:76 → 340
      7tmB1_CRF-R1; corticotropin-releasing factor receptor 1, member of the class B family of seven-transmembrane G protein-coupled receptors
      cl02422
      Location:28 → 71
      HRM; Hormone receptor domain

    4. XM_028835445.1 → XP_028691278.1  corticotropin-releasing factor receptor 1 isoform X4

      UniProtKB/TrEMBL
      H9F7K1
      Conserved Domains (1) summary
      cd15445
      Location:15 → 279
      7tmB1_CRF-R1; corticotropin-releasing factor receptor 1, member of the class B family of seven-transmembrane G protein-coupled receptors

    5. XM_015119720.2 → XP_014975206.1  corticotropin-releasing factor receptor 1 isoform X5

      UniProtKB/TrEMBL
      H9F7K1
      Conserved Domains (1) summary
      pfam00002
      Location:3 → 184
      7tm_2; 7 transmembrane receptor (Secretin family)

    6. XM_028835443.1 → XP_028691276.1  corticotropin-releasing factor receptor 1 isoform X1

      UniProtKB/TrEMBL
      F6Z590, F6Z5A6
      Related
      ENSMMUP00000005491.4, ENSMMUT00000005831.4
      Conserved Domains (2) summary
      smart00008
      Location:30 → 101
      HormR; Domain present in hormone receptors
      cd15445
      Location:106 → 370
      7tmB1_CRF-R1; corticotropin-releasing factor receptor 1, member of the class B family of seven-transmembrane G protein-coupled receptors
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q76LL8.1 GenPept UniProtKB/Swiss-Prot:Q76LL8

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.