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    ARHGEF33 Rho guanine nucleotide exchange factor 33 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 713710, updated on 17-Aug-2024

    Summary

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    Official Symbol
    ARHGEF33provided by VGNC
    Official Full Name
    Rho guanine nucleotide exchange factor 33provided by VGNC
    Primary source
    VGNC:VGNC:106128
    Locus tag
    EGK_05243
    See related
    Ensembl:ENSMMUG00000020573
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Also known as
    MORN2
    Orthologs
    human mouse all
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    Genomic context

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    See ARHGEF33 in Genome Data Viewer
    Location:
    chromosome: 13
    Exon count:
    25
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 13 NC_041766.1 (69883400..70016053, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 13 NC_027905.1 (39369364..39457308)

    Chromosome 13 - NC_041766.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC114671734 Neighboring gene SOS Ras/Rac guanine nucleotide exchange factor 1 Neighboring gene U6 spliceosomal RNA Neighboring gene U6 spliceosomal RNA Neighboring gene MORN repeat containing 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Analysis of the Macaca mulatta transcriptome and the sequence divergence between Macaca and human. Magness CL, et al. Genome Biol, 2005. PMID 15998449, Free PMC Article
    2. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
    3. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    4. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables guanyl-nucleotide exchange factor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    rho guanine nucleotide exchange factor 33
    Names
    MORN repeat containing 2
    Rho guanine nucleotide exchange factor (GEF) 33

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041766.1 Reference Mmul_10 Primary Assembly

      Range
      69883400..70016053 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028831746.1 → XP_028687579.1  rho guanine nucleotide exchange factor 33 isoform X4

      UniProtKB/TrEMBL
      F7D169
      Conserved Domains (3) summary
      COG1196
      Location:40 → 175
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      PRK10263
      Location:522 → 775
      PRK10263; DNA translocase FtsK; Provisional
      cl02571
      Location:317 → 484
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.

    2. XM_015112165.2 → XP_014967651.1  rho guanine nucleotide exchange factor 33 isoform X2

      UniProtKB/TrEMBL
      A0A5F7ZEX6
      Conserved Domains (2) summary
      pfam07106
      Location:65 → 168
      TBPIP; Tat binding protein 1(TBP-1)-interacting protein (TBPIP)
      cl02571
      Location:317 → 493
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.

    3. XM_015112164.2 → XP_014967650.1  rho guanine nucleotide exchange factor 33 isoform X1

      UniProtKB/TrEMBL
      A0A5F7ZEX6
      Conserved Domains (3) summary
      COG1196
      Location:40 → 175
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      PRK10263
      Location:522 → 775
      PRK10263; DNA translocase FtsK; Provisional
      cl02571
      Location:317 → 484
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.

    4. XM_028831743.1 → XP_028687576.1  rho guanine nucleotide exchange factor 33 isoform X1

      UniProtKB/TrEMBL
      A0A5F7ZEX6
      Conserved Domains (3) summary
      COG1196
      Location:40 → 175
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      PRK10263
      Location:522 → 775
      PRK10263; DNA translocase FtsK; Provisional
      cl02571
      Location:317 → 484
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.

    5. XM_015112174.2 → XP_014967660.1  rho guanine nucleotide exchange factor 33 isoform X9

      UniProtKB/TrEMBL
      A0A1D5QE13, A0A5F7ZEX6
      Related
      ENSMMUP00000046282.2, ENSMMUT00000063973.2
      Conserved Domains (1) summary
      cl02571
      Location:269 → 445
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.

    6. XM_028831745.1 → XP_028687578.1  rho guanine nucleotide exchange factor 33 isoform X1

      UniProtKB/TrEMBL
      A0A5F7ZEX6
      Related
      ENSMMUP00000063166.1, ENSMMUT00000104692.1
      Conserved Domains (3) summary
      COG1196
      Location:40 → 175
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      PRK10263
      Location:522 → 775
      PRK10263; DNA translocase FtsK; Provisional
      cl02571
      Location:317 → 484
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.

    7. XM_028831744.1 → XP_028687577.1  rho guanine nucleotide exchange factor 33 isoform X1

      UniProtKB/TrEMBL
      A0A5F7ZEX6
      Conserved Domains (3) summary
      COG1196
      Location:40 → 175
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      PRK10263
      Location:522 → 775
      PRK10263; DNA translocase FtsK; Provisional
      cl02571
      Location:317 → 484
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.

    8. XM_028831749.1 → XP_028687582.1  rho guanine nucleotide exchange factor 33 isoform X10

      UniProtKB/TrEMBL
      F7D169
      Conserved Domains (3) summary
      PRK10263
      Location:474 → 727
      PRK10263; DNA translocase FtsK; Provisional
      pfam07111
      Location:42 → 127
      HCR; Alpha helical coiled-coil rod protein (HCR)
      cl02571
      Location:269 → 436
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.

    9. XM_015112170.2 → XP_014967656.1  rho guanine nucleotide exchange factor 33 isoform X5

      UniProtKB/TrEMBL
      F7D169
      Conserved Domains (2) summary
      pfam07106
      Location:65 → 168
      TBPIP; Tat binding protein 1(TBP-1)-interacting protein (TBPIP)
      cl02571
      Location:317 → 493
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.

    10. XM_015112171.2 → XP_014967657.1  rho guanine nucleotide exchange factor 33 isoform X5

      UniProtKB/TrEMBL
      F7D169
      Related
      ENSMMUP00000027087.4, ENSMMUT00000028945.4
      Conserved Domains (2) summary
      pfam07106
      Location:65 → 168
      TBPIP; Tat binding protein 1(TBP-1)-interacting protein (TBPIP)
      cl02571
      Location:317 → 493
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.

    11. XM_015112173.2 → XP_014967659.1  rho guanine nucleotide exchange factor 33 isoform X8

      UniProtKB/TrEMBL
      F7D169
      Conserved Domains (2) summary
      pfam07106
      Location:65 → 168
      TBPIP; Tat binding protein 1(TBP-1)-interacting protein (TBPIP)
      cl02571
      Location:317 → 493
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.

    12. XM_015112172.2 → XP_014967658.1  rho guanine nucleotide exchange factor 33 isoform X6

      UniProtKB/TrEMBL
      F7D169
      Conserved Domains (3) summary
      COG1196
      Location:40 → 175
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      PRK10263
      Location:522 → 861
      PRK10263; DNA translocase FtsK; Provisional
      cl02571
      Location:317 → 484
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.

    13. XM_028831747.1 → XP_028687580.1  rho guanine nucleotide exchange factor 33 isoform X6

      UniProtKB/TrEMBL
      F7D169
      Conserved Domains (3) summary
      COG1196
      Location:40 → 175
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      PRK10263
      Location:522 → 861
      PRK10263; DNA translocase FtsK; Provisional
      cl02571
      Location:317 → 484
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.

    14. XM_028831748.1 → XP_028687581.1  rho guanine nucleotide exchange factor 33 isoform X7

      UniProtKB/TrEMBL
      F7D169
      Conserved Domains (3) summary
      COG1196
      Location:40 → 175
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      PRK10263
      Location:522 → 775
      PRK10263; DNA translocase FtsK; Provisional
      cl02571
      Location:317 → 484
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.

    15. XM_015112169.2 → XP_014967655.1  rho guanine nucleotide exchange factor 33 isoform X5

      UniProtKB/TrEMBL
      F7D169
      Conserved Domains (2) summary
      pfam07106
      Location:65 → 168
      TBPIP; Tat binding protein 1(TBP-1)-interacting protein (TBPIP)
      cl02571
      Location:317 → 493
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.

    16. XM_015112168.2 → XP_014967654.1  rho guanine nucleotide exchange factor 33 isoform X5

      UniProtKB/TrEMBL
      F7D169
      Conserved Domains (2) summary
      pfam07106
      Location:65 → 168
      TBPIP; Tat binding protein 1(TBP-1)-interacting protein (TBPIP)
      cl02571
      Location:317 → 493
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.

    17. XM_015112175.2 → XP_014967661.1  rho guanine nucleotide exchange factor 33 isoform X10

      UniProtKB/TrEMBL
      F7D169
      Conserved Domains (3) summary
      PRK10263
      Location:474 → 727
      PRK10263; DNA translocase FtsK; Provisional
      pfam07111
      Location:42 → 127
      HCR; Alpha helical coiled-coil rod protein (HCR)
      cl02571
      Location:269 → 436
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.

    18. XM_015112167.2 → XP_014967653.1  rho guanine nucleotide exchange factor 33 isoform X3

      UniProtKB/TrEMBL
      A0A5F7ZVY1
      Related
      ENSMMUP00000069815.1, ENSMMUT00000107219.1
      Conserved Domains (2) summary
      pfam07106
      Location:65 → 168
      TBPIP; Tat binding protein 1(TBP-1)-interacting protein (TBPIP)
      cl02571
      Location:317 → 493
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001190731.1: Suppressed sequence

      Description
      NM_001190731.1: This RefSeq was suppressed temporarily based on the calculation that the encoded protein was shorter than proteins from the putative ortholog from human: ARHGEF33 (GeneID:100271715).
    Nucleotide Protein
    Heading Accession and Version

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