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    WWC1 WW and C2 domain containing 1 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 698875, updated on 17-Aug-2024

    Summary

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    Official Symbol
    WWC1provided by VGNC
    Official Full Name
    WW and C2 domain containing 1provided by VGNC
    Primary source
    VGNC:VGNC:79809
    See related
    Ensembl:ENSMMUG00000007457
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See WWC1 in Genome Data Viewer
    Location:
    chromosome: 6
    Exon count:
    24
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 6 NC_041759.1 (165674588..165849283)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 6 NC_027898.1 (166527181..166703263)

    Chromosome 6 - NC_041759.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC114678965 Neighboring gene teneurin transmembrane protein 2 Neighboring gene small nucleolar RNA SNORA40 Neighboring gene uncharacterized LOC106999025 Neighboring gene uncharacterized LOC114678967 Neighboring gene arginyl-tRNA synthetase 1 Neighboring gene pantothenate kinase 3 Neighboring gene fibrillarin like 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables kinase binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables molecular adaptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cell migration IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of organ growth IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of hippo signaling IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    protein KIBRA

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041759.1 Reference Mmul_10 Primary Assembly

      Range
      165674588..165849283
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015141371.2 → XP_014996857.1  protein KIBRA isoform X1

      UniProtKB/TrEMBL
      G7MVU8
      Conserved Domains (4) summary
      cd08680
      Location:660 → 783
      C2_Kibra; C2 domain found in Human protein Kibra
      cd00201
      Location:9 → 39
      WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
      pfam00397
      Location:55 → 84
      WW; WW domain
      cl11961
      Location:368 → 420
      ALDH-SF; NAD(P)+-dependent aldehyde dehydrogenase superfamily

    2. XM_015141373.2 → XP_014996859.1  protein KIBRA isoform X3

      UniProtKB/TrEMBL
      G7MVU8
      Conserved Domains (4) summary
      cd08680
      Location:660 → 783
      C2_Kibra; C2 domain found in Human protein Kibra
      cd00201
      Location:9 → 39
      WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
      pfam00397
      Location:55 → 84
      WW; WW domain
      cl11961
      Location:368 → 420
      ALDH-SF; NAD(P)+-dependent aldehyde dehydrogenase superfamily

    3. XM_015141372.2 → XP_014996858.1  protein KIBRA isoform X2

      UniProtKB/TrEMBL
      G7MVU8
      Related
      ENSMMUP00000009784.4, ENSMMUT00000010425.4
      Conserved Domains (4) summary
      cd08680
      Location:660 → 783
      C2_Kibra; C2 domain found in Human protein Kibra
      cd00201
      Location:9 → 39
      WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
      pfam00397
      Location:55 → 84
      WW; WW domain
      cl11961
      Location:368 → 420
      ALDH-SF; NAD(P)+-dependent aldehyde dehydrogenase superfamily

    4. XM_015141374.2 → XP_014996860.1  protein KIBRA isoform X4

      UniProtKB/TrEMBL
      G7MVU8
      Conserved Domains (4) summary
      cd08680
      Location:660 → 783
      C2_Kibra; C2 domain found in Human protein Kibra
      cd00201
      Location:9 → 39
      WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
      pfam00397
      Location:55 → 84
      WW; WW domain
      cl11961
      Location:368 → 420
      ALDH-SF; NAD(P)+-dependent aldehyde dehydrogenase superfamily

    5. XM_028849904.1 → XP_028705737.1  protein KIBRA isoform X6

      UniProtKB/TrEMBL
      F6SW62
      Conserved Domains (2) summary
      cd08680
      Location:571 → 694
      C2_Kibra; C2 domain found in Human protein Kibra
      COG1196
      Location:65 → 322
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

    6. XM_015141375.2 → XP_014996861.1  protein KIBRA isoform X7

      UniProtKB/TrEMBL
      F6SW62
      Conserved Domains (2) summary
      cd08680
      Location:566 → 689
      C2_Kibra; C2 domain found in Human protein Kibra
      cl11961
      Location:274 → 326
      ALDH-SF; NAD(P)+-dependent aldehyde dehydrogenase superfamily

    7. XM_028849905.1 → XP_028705738.1  protein KIBRA isoform X6

      UniProtKB/TrEMBL
      F6SW62
      Conserved Domains (2) summary
      cd08680
      Location:571 → 694
      C2_Kibra; C2 domain found in Human protein Kibra
      COG1196
      Location:65 → 322
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

    8. XM_028849903.1 → XP_028705736.1  protein KIBRA isoform X5

      UniProtKB/TrEMBL
      G7MVU8
      Conserved Domains (3) summary
      cd08680
      Location:621 → 744
      C2_Kibra; C2 domain found in Human protein Kibra
      TIGR04211
      Location:256 → 383
      SH3_and_anchor; SH3 domain protein
      pfam00397
      Location:16 → 45
      WW; WW domain
    Nucleotide Protein
    Heading Accession and Version

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