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    INPP5B inositol polyphosphate-5-phosphatase B [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 716851, updated on 17-Aug-2024

    Summary

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    Official Symbol
    INPP5Bprovided by VGNC
    Official Full Name
    inositol polyphosphate-5-phosphatase Bprovided by VGNC
    Primary source
    VGNC:VGNC:73750
    See related
    Ensembl:ENSMMUG00000023277
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See INPP5B in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    24
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 1 NC_041754.1 (186641241..186717876)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 1 NC_027893.1 (37068216..37150156, complement)

    Chromosome 1 - NC_041754.1Genomic Context describing neighboring genes Neighboring gene U6 spliceosomal RNA Neighboring gene splicing factor 3a subunit 3 Neighboring gene U6 spliceosomal RNA Neighboring gene metal regulatory transcription factor 1 Neighboring gene chromosome 1 C1orf122 homolog Neighboring gene yrdC N6-threonylcarbamoyltransferase domain containing

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables inositol-1,4,5-trisphosphate 5-phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in phosphatidylinositol dephosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    LOW QUALITY PROTEIN: type II inositol 1,4,5-trisphosphate 5-phosphatase
    Names
    inositol polyphosphate-5-phosphatase, 75kDa
    type II inositol-1,4,5-trisphosphate 5-phosphatase

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041754.1 Reference Mmul_10 Primary Assembly

      Range
      186641241..186717876
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015135734.2 → XP_014991220.2  LOW QUALITY PROTEIN: type II inositol 1,4,5-trisphosphate 5-phosphatase

      UniProtKB/TrEMBL
      A0A1D5Q176, H9FU22
      Related
      ENSMMUP00000041788.2, ENSMMUT00000069187.2
      Conserved Domains (3) summary
      cd09093
      Location:345 → 638
      INPP5c_INPP5B; Catalytic inositol polyphosphate 5-phosphatase (INPP5c) domain of Type II inositol polyphosphate 5-phosphatase I, Oculocerebrorenal syndrome of Lowe 1, and related proteins
      cd04380
      Location:772 → 992
      RhoGAP_OCRL1; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in OCRL1-like proteins. OCRL1 (oculocerebrorenal syndrome of Lowe 1)-like proteins contain two conserved domains: a central inositol polyphosphate 5-phosphatase domain and ...
      pfam16776
      Location:6 → 150
      INPP5B_PH; Type II inositol 1,4,5-trisphosphate 5-phosphatase PH domain
    Nucleotide Protein
    Heading Accession and Version

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