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    PRPF19 pre-mRNA processing factor 19 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 696170, updated on 17-Aug-2024

    Summary

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    Official Symbol
    PRPF19provided by VGNC
    Official Full Name
    pre-mRNA processing factor 19provided by VGNC
    Primary source
    VGNC:VGNC:76281
    Locus tag
    EGK_06157
    See related
    Ensembl:ENSMMUG00000014530
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See PRPF19 in Genome Data Viewer
    Location:
    chromosome: 14
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 14 NC_041767.1 (13328872..13344653)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 14 NC_027906.1 (13376796..13392239)

    Chromosome 14 - NC_041767.1Genomic Context describing neighboring genes Neighboring gene solute carrier family 15 member 3 Neighboring gene transmembrane protein 132A Neighboring gene transmembrane protein 109 Neighboring gene uncharacterized LOC106993224 Neighboring gene zona pellucida glycoprotein 1 Neighboring gene prostaglandin D2 receptor 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
    2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables ubiquitin protein ligase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in DNA repair IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in mRNA splicing, via spliceosome IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein ubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of Prp19 complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of U2-type catalytic step 1 spliceosome IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    pre-mRNA-processing factor 19
    Names
    PRP19/PSO4 pre-mRNA processing factor 19 homolog
    PRP19/PSO4-like protein
    NP_001248010.1
    XP_028688358.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001261081.1 → NP_001248010.1  pre-mRNA-processing factor 19

      See identical proteins and their annotated locations for NP_001248010.1

      Status: PROVISIONAL

      Source sequence(s)
      JV044753
      UniProtKB/TrEMBL
      A0A1D5QJ61, A0A8J8XDF3, F7GAB7, G7ND29
      Related
      ENSMMUP00000048083.1, ENSMMUT00000069043.2
      Conserved Domains (4) summary
      cd00200
      Location:223 → 503
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:224 → 262
      7WD40; WD40 repeat [structural motif]
      cd16656
      Location:4 → 56
      RING-Ubox_PRP19; U-box domain, a modified RING finger, found in pre-mRNA-processing factor 19 (Prp19) and similar proteins
      pfam08606
      Location:69 → 133
      Prp19; Prp19/Pso4-like

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041767.1 Reference Mmul_10 Primary Assembly

      Range
      13328872..13344653
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028832525.1 → XP_028688358.1  pre-mRNA-processing factor 19 isoform X1

      UniProtKB/TrEMBL
      F7GAB7
      Conserved Domains (3) summary
      cd00200
      Location:138 → 418
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:139 → 177
      7WD40; WD40 repeat [structural motif]
      pfam08606
      Location:1 → 48
      Prp19; Prp19/Pso4-like
    Nucleotide Protein
    Heading Accession and Version

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