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    SLC12A4 solute carrier family 12 member 4 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 701196, updated on 17-Aug-2024

    Summary

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    Official Symbol
    SLC12A4provided by VGNC
    Official Full Name
    solute carrier family 12 member 4provided by VGNC
    Primary source
    VGNC:VGNC:77388
    See related
    Ensembl:ENSMMUG00000008491
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See SLC12A4 in Genome Data Viewer
    Location:
    chromosome: 20
    Exon count:
    26
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 20 NC_041773.1 (55163034..55187578, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 20 NC_027912.1 (52310994..52335492, complement)

    Chromosome 20 - NC_041773.1Genomic Context describing neighboring genes Neighboring gene chymotrypsin like Neighboring gene proteasome 20S subunit beta 10 Neighboring gene lecithin-cholesterol acyltransferase Neighboring gene uncharacterized LOC114674473 Neighboring gene dipeptidase 3 Neighboring gene dipeptidase 2 Neighboring gene lysine--tRNA ligase-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables potassium:chloride symporter activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cell volume homeostasis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in chemical synaptic transmission IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in chloride ion homeostasis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in chloride transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in potassium ion homeostasis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in potassium ion import across plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    solute carrier family 12 member 4
    Names
    solute carrier family 12 (potassium/chloride transporters), member 4

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041773.1 Reference Mmul_10 Primary Assembly

      Range
      55163034..55187578 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028841536.1 → XP_028697369.1  solute carrier family 12 member 4 isoform X3

      UniProtKB/TrEMBL
      F6R193
      Related
      ENSMMUP00000025548.4, ENSMMUT00000027312.4
      Conserved Domains (1) summary
      TIGR00930
      Location:1 → 968
      2a30; K-Cl cotransporter

    2. XM_015126445.2 → XP_014981931.1  solute carrier family 12 member 4 isoform X1

      UniProtKB/TrEMBL
      A0A1D5QCH9, H9ETV5, I0FUD0
      Related
      ENSMMUP00000045748.2, ENSMMUT00000065445.2
      Conserved Domains (1) summary
      TIGR00930
      Location:42 → 1085
      2a30; K-Cl cotransporter

    3. XM_002802533.3 → XP_002802579.2  solute carrier family 12 member 4 isoform X2

      UniProtKB/TrEMBL
      G7NQ77
      Conserved Domains (3) summary
      TIGR00930
      Location:11 → 1054
      2a30; K-Cl cotransporter
      pfam03522
      Location:678 → 1054
      SLC12; Solute carrier family 12
      cl00456
      Location:111 → 272
      SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain
    Nucleotide Protein
    Heading Accession and Version

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