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    HEXA hexosaminidase subunit alpha [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 698251, updated on 1-Aug-2024

    Summary

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    Gene symbol
    HEXA
    Gene description
    hexosaminidase subunit alpha
    Locus tag
    EGK_17654
    See related
    Ensembl:ENSMMUG00000046622
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See HEXA in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 7 NC_041760.1 (49058131..49113621, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 7 NC_027899.1 (49334959..49390928, complement)

    Chromosome 7 - NC_041760.1Genomic Context describing neighboring genes Neighboring gene poly(ADP-ribose) polymerase family member 6 Neighboring gene CUGBP Elav-like family member 6 Neighboring gene transmembrane protein 202 Neighboring gene prohibitin pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
    2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables beta-N-acetylhexosaminidase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in carbohydrate metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in ganglioside catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in glycosaminoglycan metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    beta-hexosaminidase subunit alpha
    Names
    beta-hexosaminidase subunit alpha preproprotein
    NP_001248458.1
    XP_014998083.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001261529.1 → NP_001248458.1  beta-hexosaminidase subunit alpha precursor

      See identical proteins and their annotated locations for NP_001248458.1

      Status: PROVISIONAL

      Source sequence(s)
      JV046899
      UniProtKB/TrEMBL
      A0A5F7ZC15, I0FR94
      Related
      ENSMMUP00000070292.1, ENSMMUT00000100055.1
      Conserved Domains (2) summary
      cd06562
      Location:167 → 511
      GH20_HexA_HexB-like; Beta-N-acetylhexosaminidases catalyze the removal of beta-1,4-linked N-acetyl-D-hexosamine residues from the non-reducing ends of N-acetyl-beta-D-hexosaminides including N-acetylglucosides and N-acetylgalactosides. The hexA and hexB genes encode the ...
      pfam14845
      Location:23 → 145
      Glycohydro_20b2; beta-acetyl hexosaminidase like

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041760.1 Reference Mmul_10 Primary Assembly

      Range
      49058131..49113621 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015142597.2 → XP_014998083.1  beta-hexosaminidase subunit alpha isoform X1

      UniProtKB/TrEMBL
      A0A5F7ZC15, F7GQ07
      Related
      ENSMMUP00000033450.2, ENSMMUT00000040385.3
      Conserved Domains (2) summary
      cd06562
      Location:167 → 509
      GH20_HexA_HexB-like; Beta-N-acetylhexosaminidases catalyze the removal of beta-1,4-linked N-acetyl-D-hexosamine residues from the non-reducing ends of N-acetyl-beta-D-hexosaminides including N-acetylglucosides and N-acetylgalactosides. The hexA and hexB genes encode the ...
      pfam14845
      Location:23 → 145
      Glycohydro_20b2; beta-acetyl hexosaminidase like
    Nucleotide Protein
    Heading Accession and Version

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