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    WNK2 WNK lysine deficient protein kinase 2 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 717275, updated on 17-Aug-2024

    Summary

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    Official Symbol
    WNK2provided by VGNC
    Official Full Name
    WNK lysine deficient protein kinase 2provided by VGNC
    Primary source
    VGNC:VGNC:78961
    See related
    Ensembl:ENSMMUG00000013881
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See WNK2 in Genome Data Viewer
    Location:
    chromosome: 15
    Exon count:
    32
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 15 NC_041768.1 (108149832..108290973)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 15 NC_027907.1 (43317199..43455500)

    Chromosome 15 - NC_041768.1Genomic Context describing neighboring genes Neighboring gene caspase recruitment domain family member 19 Neighboring gene ninjurin 1 Neighboring gene Putative uncharacterized protein C9orf129 homolog Neighboring gene U6 spliceosomal RNA Neighboring gene uncharacterized LOC106993690

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables chloride channel inhibitor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables potassium channel inhibitor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in intracellular signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in monoatomic ion homeostasis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of sodium ion transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of potassium ion import across plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of sodium ion transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    serine/threonine-protein kinase WNK2
    XP_014972762.2
    XP_028691171.1
    XP_028691172.1
    XP_028691173.1
    XP_028691174.1
    XP_028691175.1
    XP_028691176.1
    XP_028691177.1
    XP_028691178.1
    XP_028691179.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041768.1 Reference Mmul_10 Primary Assembly

      Range
      108149832..108290973
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028835342.1 → XP_028691175.1  serine/threonine-protein kinase WNK2 isoform X6

      UniProtKB/TrEMBL
      A0A5F8APW0, F6RC70
      Related
      ENSMMUP00000018248.4, ENSMMUT00000019487.4
      Conserved Domains (2) summary
      cd14032
      Location:193 → 458
      STKc_WNK2_like; Catalytic domain of With No Lysine (WNK) 2-like Serine/Threonine kinases
      pfam12202
      Location:474 → 537
      OSR1_C; Oxidative-stress-responsive kinase 1 C-terminal domain

    2. XM_015117276.2 → XP_014972762.2  serine/threonine-protein kinase WNK2 isoform X1

      UniProtKB/TrEMBL
      F6RC61
      Related
      ENSMMUP00000018249.4, ENSMMUT00000019488.4
      Conserved Domains (2) summary
      cd14032
      Location:193 → 458
      STKc_WNK2_like; Catalytic domain of With No Lysine (WNK) 2-like Serine/Threonine kinases
      pfam12202
      Location:474 → 537
      OSR1_C; Oxidative-stress-responsive kinase 1 C-terminal domain

    3. XM_028835341.1 → XP_028691174.1  serine/threonine-protein kinase WNK2 isoform X5

      UniProtKB/TrEMBL
      A0A5F8APW0
      Conserved Domains (2) summary
      cd14032
      Location:193 → 458
      STKc_WNK2_like; Catalytic domain of With No Lysine (WNK) 2-like Serine/Threonine kinases
      pfam12202
      Location:474 → 537
      OSR1_C; Oxidative-stress-responsive kinase 1 C-terminal domain

    4. XM_028835340.1 → XP_028691173.1  serine/threonine-protein kinase WNK2 isoform X4

      UniProtKB/TrEMBL
      F6RC61
      Conserved Domains (2) summary
      cd14032
      Location:193 → 458
      STKc_WNK2_like; Catalytic domain of With No Lysine (WNK) 2-like Serine/Threonine kinases
      pfam12202
      Location:474 → 537
      OSR1_C; Oxidative-stress-responsive kinase 1 C-terminal domain

    5. XM_028835343.1 → XP_028691176.1  serine/threonine-protein kinase WNK2 isoform X7

      UniProtKB/TrEMBL
      F6RC61
      Related
      ENSMMUP00000043675.2, ENSMMUT00000053452.2
      Conserved Domains (2) summary
      cd14032
      Location:193 → 458
      STKc_WNK2_like; Catalytic domain of With No Lysine (WNK) 2-like Serine/Threonine kinases
      pfam12202
      Location:474 → 537
      OSR1_C; Oxidative-stress-responsive kinase 1 C-terminal domain

    6. XM_028835345.1 → XP_028691178.1  serine/threonine-protein kinase WNK2 isoform X9

      UniProtKB/TrEMBL
      F6RC61
      Conserved Domains (2) summary
      cd14032
      Location:193 → 458
      STKc_WNK2_like; Catalytic domain of With No Lysine (WNK) 2-like Serine/Threonine kinases
      pfam12202
      Location:474 → 537
      OSR1_C; Oxidative-stress-responsive kinase 1 C-terminal domain

    7. XM_028835346.1 → XP_028691179.1  serine/threonine-protein kinase WNK2 isoform X10

      UniProtKB/TrEMBL
      F6RC61
      Conserved Domains (2) summary
      cd14032
      Location:193 → 458
      STKc_WNK2_like; Catalytic domain of With No Lysine (WNK) 2-like Serine/Threonine kinases
      pfam12202
      Location:474 → 537
      OSR1_C; Oxidative-stress-responsive kinase 1 C-terminal domain

    8. XM_028835338.1 → XP_028691171.1  serine/threonine-protein kinase WNK2 isoform X2

      UniProtKB/TrEMBL
      F6RC61
      Conserved Domains (2) summary
      cd14032
      Location:193 → 458
      STKc_WNK2_like; Catalytic domain of With No Lysine (WNK) 2-like Serine/Threonine kinases
      pfam12202
      Location:474 → 537
      OSR1_C; Oxidative-stress-responsive kinase 1 C-terminal domain

    9. XM_028835339.1 → XP_028691172.1  serine/threonine-protein kinase WNK2 isoform X3

      UniProtKB/TrEMBL
      F6RC61
      Conserved Domains (2) summary
      cd14032
      Location:193 → 458
      STKc_WNK2_like; Catalytic domain of With No Lysine (WNK) 2-like Serine/Threonine kinases
      pfam12202
      Location:474 → 537
      OSR1_C; Oxidative-stress-responsive kinase 1 C-terminal domain

    10. XM_028835344.1 → XP_028691177.1  serine/threonine-protein kinase WNK2 isoform X8

      UniProtKB/TrEMBL
      A0A5F8APW0
      Conserved Domains (2) summary
      cd14032
      Location:193 → 458
      STKc_WNK2_like; Catalytic domain of With No Lysine (WNK) 2-like Serine/Threonine kinases
      pfam12202
      Location:474 → 537
      OSR1_C; Oxidative-stress-responsive kinase 1 C-terminal domain
    Nucleotide Protein
    Heading Accession and Version

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