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    OAS3 2'-5'-oligoadenylate synthetase 3 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 712342, updated on 17-Aug-2024

    Summary

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    Official Symbol
    OAS3provided by VGNC
    Official Full Name
    2'-5'-oligoadenylate synthetase 3provided by VGNC
    Primary source
    VGNC:VGNC:100083
    See related
    Ensembl:ENSMMUG00000046639
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See OAS3 in Genome Data Viewer
    Location:
    chromosome: 11
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 11 NC_041764.1 (112661047..112689871)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 11 NC_027903.1 (112978075..113006748)

    Chromosome 11 - NC_041764.1Genomic Context describing neighboring genes Neighboring gene rabphilin 3A Neighboring gene 2'-5'-oligoadenylate synthetase 1 Neighboring gene mitochondrial inner membrane protease subunit 1 pseudogene Neighboring gene 2'-5'-oligoadenylate synthetase 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables 2'-5'-oligoadenylate synthetase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables double-stranded RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in defense response to virus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of viral genome replication IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of ribonuclease activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    2'-5'-oligoadenylate synthase 3
    Names
    2'-5'-oligoadenylate synthetase 3, 100kDa
    XP_015008354.1
    XP_015008355.1
    XP_015008356.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041764.1 Reference Mmul_10 Primary Assembly

      Range
      112661047..112689871
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015152870.2 → XP_015008356.1  2'-5'-oligoadenylate synthase 3 isoform X3

      UniProtKB/TrEMBL
      A0A5F7ZVK6
      Conserved Domains (2) summary
      cd05400
      Location:769 → 896
      NT_2-5OAS_ClassI-CCAase; Nucleotidyltransferase (NT) domain of 2'5'-oligoadenylate (2-5A)synthetase (2-5OAS) and class I CCA-adding enzyme
      pfam10421
      Location:161 → 343
      OAS1_C; 2'-5'-oligoadenylate synthetase 1, domain 2, C-terminus

    2. XM_015152869.2 → XP_015008355.1  2'-5'-oligoadenylate synthase 3 isoform X2

      UniProtKB/TrEMBL
      I0FS28
      Conserved Domains (3) summary
      cd05400
      Location:714 → 893
      NT_2-5OAS_ClassI-CCAase; Nucleotidyltransferase (NT) domain of 2'5'-oligoadenylate (2-5A)synthetase (2-5OAS) and class I CCA-adding enzyme
      pfam10421
      Location:848 → 1029
      OAS1_C; 2'-5'-oligoadenylate synthetase 1, domain 2, C-terminus
      cl11966
      Location:50 → 113
      NT_Pol-beta-like; Nucleotidyltransferase (NT) domain of DNA polymerase beta and similar proteins

    3. XM_015152868.2 → XP_015008354.1  2'-5'-oligoadenylate synthase 3 isoform X1

      UniProtKB/TrEMBL
      A0A1D5QJ25, I0FS28
      Related
      ENSMMUP00000048047.1, ENSMMUT00000065666.2
      Conserved Domains (2) summary
      cd05400
      Location:769 → 948
      NT_2-5OAS_ClassI-CCAase; Nucleotidyltransferase (NT) domain of 2'5'-oligoadenylate (2-5A)synthetase (2-5OAS) and class I CCA-adding enzyme
      pfam10421
      Location:903 → 1084
      OAS1_C; 2'-5'-oligoadenylate synthetase 1, domain 2, C-terminus
    Nucleotide Protein
    Heading Accession and Version

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