U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    PDE5A phosphodiesterase 5A [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 705592, updated on 17-Aug-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    PDE5Aprovided by VGNC
    Official Full Name
    phosphodiesterase 5Aprovided by VGNC
    Primary source
    VGNC:VGNC:75918
    See related
    Ensembl:ENSMMUG00000007305
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See PDE5A in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    23
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 5 NC_041758.1 (117387207..117516195, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 5 NC_027897.1 (118317078..118446570, complement)

    Chromosome 5 - NC_041758.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC106998477 Neighboring gene allregulin Neighboring gene fatty acid binding protein 2 Neighboring gene uncharacterized LOC114678387 Neighboring gene small nucleolar RNA SNORA11 Neighboring gene uncharacterized LOC106998479 Neighboring gene uncharacterized LOC106998449

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables 3',5'-cyclic-GMP phosphodiesterase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    cGMP-specific 3',5'-cyclic phosphodiesterase
    Names
    phosphodiesterase 5A, cGMP-specific
    XP_001099444.2
    XP_001099553.4
    XP_001099652.2

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041758.1 Reference Mmul_10 Primary Assembly

      Range
      117387207..117516195 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001099652.4 → XP_001099652.2  cGMP-specific 3',5'-cyclic phosphodiesterase isoform X1

      UniProtKB/TrEMBL
      F7F6V2, G7MRV8
      Related
      ENSMMUP00000009576.4, ENSMMUT00000010207.4
      Conserved Domains (2) summary
      smart00065
      Location:164 → 321
      GAF; Domain present in phytochromes and cGMP-specific phosphodiesterases
      pfam00233
      Location:612 → 847
      PDEase_I; 3'5'-cyclic nucleotide phosphodiesterase

    2. XM_001099444.4 → XP_001099444.2  cGMP-specific 3',5'-cyclic phosphodiesterase isoform X3

      UniProtKB/TrEMBL
      G7MRV8
      Conserved Domains (2) summary
      smart00065
      Location:112 → 269
      GAF; Domain present in phytochromes and cGMP-specific phosphodiesterases
      pfam00233
      Location:560 → 795
      PDEase_I; 3'5'-cyclic nucleotide phosphodiesterase

    3. XM_001099553.4 → XP_001099553.4  cGMP-specific 3',5'-cyclic phosphodiesterase isoform X2

      UniProtKB/TrEMBL
      A0A1D5R6Z5, G7MRV8
      Related
      ENSMMUP00000056083.2, ENSMMUT00000072826.2
      Conserved Domains (2) summary
      smart00065
      Location:122 → 279
      GAF; Domain present in phytochromes and cGMP-specific phosphodiesterases
      pfam00233
      Location:570 → 805
      PDEase_I; 3'5'-cyclic nucleotide phosphodiesterase
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.