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    RHOBTB1 Rho related BTB domain containing 1 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 699132, updated on 17-Aug-2024

    Summary

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    Official Symbol
    RHOBTB1provided by VGNC
    Official Full Name
    Rho related BTB domain containing 1provided by VGNC
    Primary source
    VGNC:VGNC:76768
    Locus tag
    EGK_19831
    See related
    Ensembl:ENSMMUG00000021400
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See RHOBTB1 in Genome Data Viewer
    Location:
    chromosome: 9
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 9 NC_041762.1 (76984762..77118093)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 9 NC_027901.1 (71734683..71869134)

    Chromosome 9 - NC_041762.1Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA SNORD55/SNORD39 Neighboring gene uncharacterized LOC114670135 Neighboring gene uncharacterized LOC114669985 Neighboring gene U2 spliceosomal RNA Neighboring gene cyclin dependent kinase 1 Neighboring gene ADP-ribosylation factor-like protein 4A Neighboring gene ankyrin 3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
    2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables GTP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables GTPase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables ubiquitin protein ligase binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in proteasome-mediated ubiquitin-dependent protein catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in small GTPase-mediated signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    rho-related BTB domain-containing protein 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001266985.1 → NP_001253914.1  rho-related BTB domain-containing protein 1

      See identical proteins and their annotated locations for NP_001253914.1

      Status: PROVISIONAL

      Source sequence(s)
      JV635514
      UniProtKB/TrEMBL
      A0A8J8YGF6, F7FD59, G7N2E8, H9F5Y9
      Related
      ENSMMUP00000028191.2, ENSMMUT00000030123.4
      Conserved Domains (4) summary
      cd01873
      Location:13 → 207
      RhoBTB; RhoBTB protein is an atypical member of the Rho family of small GTPases
      cd18355
      Location:248 → 460
      BTB1_POZ_RHOBTB1; first BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Rho-related BTB domain-containing protein 1 (RhoBTB1)
      cd18358
      Location:465 → 590
      BTB2_POZ_RHOBTB1; second BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Rho-related BTB domain-containing protein 1 (RhoBTB1)
      cd18530
      Location:593 → 692
      BACK_RHOBTB1; BACK (BTB and C-terminal Kelch) domain found in Rho-related BTB domain-containing protein 1 (RhoBTB1)

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041762.1 Reference Mmul_10 Primary Assembly

      Range
      76984762..77118093
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028853337.1 → XP_028709170.1  rho-related BTB domain-containing protein 1 isoform X1

      UniProtKB/TrEMBL
      A0A8J8YGF6, F7FD59, G7N2E8, H9F5Y9
      Conserved Domains (4) summary
      cd01873
      Location:13 → 207
      RhoBTB; RhoBTB protein is an atypical member of the Rho family of small GTPases
      cd18355
      Location:248 → 460
      BTB1_POZ_RHOBTB1; first BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Rho-related BTB domain-containing protein 1 (RhoBTB1)
      cd18358
      Location:465 → 590
      BTB2_POZ_RHOBTB1; second BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Rho-related BTB domain-containing protein 1 (RhoBTB1)
      cd18530
      Location:593 → 692
      BACK_RHOBTB1; BACK (BTB and C-terminal Kelch) domain found in Rho-related BTB domain-containing protein 1 (RhoBTB1)

    2. XM_028853336.1 → XP_028709169.1  rho-related BTB domain-containing protein 1 isoform X1

      UniProtKB/TrEMBL
      A0A8J8YGF6, F7FD59, G7N2E8, H9F5Y9
      Conserved Domains (4) summary
      cd01873
      Location:13 → 207
      RhoBTB; RhoBTB protein is an atypical member of the Rho family of small GTPases
      cd18355
      Location:248 → 460
      BTB1_POZ_RHOBTB1; first BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Rho-related BTB domain-containing protein 1 (RhoBTB1)
      cd18358
      Location:465 → 590
      BTB2_POZ_RHOBTB1; second BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Rho-related BTB domain-containing protein 1 (RhoBTB1)
      cd18530
      Location:593 → 692
      BACK_RHOBTB1; BACK (BTB and C-terminal Kelch) domain found in Rho-related BTB domain-containing protein 1 (RhoBTB1)

    3. XM_028853333.1 → XP_028709166.1  rho-related BTB domain-containing protein 1 isoform X1

      UniProtKB/TrEMBL
      A0A8J8YGF6, F7FD59, G7N2E8, H9F5Y9
      Conserved Domains (4) summary
      cd01873
      Location:13 → 207
      RhoBTB; RhoBTB protein is an atypical member of the Rho family of small GTPases
      cd18355
      Location:248 → 460
      BTB1_POZ_RHOBTB1; first BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Rho-related BTB domain-containing protein 1 (RhoBTB1)
      cd18358
      Location:465 → 590
      BTB2_POZ_RHOBTB1; second BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Rho-related BTB domain-containing protein 1 (RhoBTB1)
      cd18530
      Location:593 → 692
      BACK_RHOBTB1; BACK (BTB and C-terminal Kelch) domain found in Rho-related BTB domain-containing protein 1 (RhoBTB1)

    4. XM_028853343.1 → XP_028709176.1  rho-related BTB domain-containing protein 1 isoform X1

      UniProtKB/TrEMBL
      A0A8J8YGF6, F7FD59, G7N2E8, H9F5Y9
      Related
      ENSMMUP00000080388.1, ENSMMUT00000093162.1
      Conserved Domains (4) summary
      cd01873
      Location:13 → 207
      RhoBTB; RhoBTB protein is an atypical member of the Rho family of small GTPases
      cd18355
      Location:248 → 460
      BTB1_POZ_RHOBTB1; first BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Rho-related BTB domain-containing protein 1 (RhoBTB1)
      cd18358
      Location:465 → 590
      BTB2_POZ_RHOBTB1; second BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Rho-related BTB domain-containing protein 1 (RhoBTB1)
      cd18530
      Location:593 → 692
      BACK_RHOBTB1; BACK (BTB and C-terminal Kelch) domain found in Rho-related BTB domain-containing protein 1 (RhoBTB1)

    5. XM_028853345.1 → XP_028709178.1  rho-related BTB domain-containing protein 1 isoform X2

      UniProtKB/TrEMBL
      H9F5Y9
      Conserved Domains (4) summary
      cd18355
      Location:128 → 340
      BTB1_POZ_RHOBTB1; first BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Rho-related BTB domain-containing protein 1 (RhoBTB1)
      cd18358
      Location:345 → 470
      BTB2_POZ_RHOBTB1; second BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Rho-related BTB domain-containing protein 1 (RhoBTB1)
      cd18530
      Location:473 → 572
      BACK_RHOBTB1; BACK (BTB and C-terminal Kelch) domain found in Rho-related BTB domain-containing protein 1 (RhoBTB1)
      cl21455
      Location:1 → 87
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

    6. XM_028853338.1 → XP_028709171.1  rho-related BTB domain-containing protein 1 isoform X1

      UniProtKB/TrEMBL
      A0A8J8YGF6, F7FD59, G7N2E8, H9F5Y9
      Related
      ENSMMUP00000035799.1, ENSMMUT00000042786.3
      Conserved Domains (4) summary
      cd01873
      Location:13 → 207
      RhoBTB; RhoBTB protein is an atypical member of the Rho family of small GTPases
      cd18355
      Location:248 → 460
      BTB1_POZ_RHOBTB1; first BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Rho-related BTB domain-containing protein 1 (RhoBTB1)
      cd18358
      Location:465 → 590
      BTB2_POZ_RHOBTB1; second BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Rho-related BTB domain-containing protein 1 (RhoBTB1)
      cd18530
      Location:593 → 692
      BACK_RHOBTB1; BACK (BTB and C-terminal Kelch) domain found in Rho-related BTB domain-containing protein 1 (RhoBTB1)

    7. XM_028853347.1 → XP_028709180.1  rho-related BTB domain-containing protein 1 isoform X2

      UniProtKB/TrEMBL
      H9F5Y9
      Conserved Domains (4) summary
      cd18355
      Location:128 → 340
      BTB1_POZ_RHOBTB1; first BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Rho-related BTB domain-containing protein 1 (RhoBTB1)
      cd18358
      Location:345 → 470
      BTB2_POZ_RHOBTB1; second BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Rho-related BTB domain-containing protein 1 (RhoBTB1)
      cd18530
      Location:473 → 572
      BACK_RHOBTB1; BACK (BTB and C-terminal Kelch) domain found in Rho-related BTB domain-containing protein 1 (RhoBTB1)
      cl21455
      Location:1 → 87
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

    8. XM_028853346.1 → XP_028709179.1  rho-related BTB domain-containing protein 1 isoform X2

      UniProtKB/TrEMBL
      H9F5Y9
      Conserved Domains (4) summary
      cd18355
      Location:128 → 340
      BTB1_POZ_RHOBTB1; first BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Rho-related BTB domain-containing protein 1 (RhoBTB1)
      cd18358
      Location:345 → 470
      BTB2_POZ_RHOBTB1; second BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Rho-related BTB domain-containing protein 1 (RhoBTB1)
      cd18530
      Location:473 → 572
      BACK_RHOBTB1; BACK (BTB and C-terminal Kelch) domain found in Rho-related BTB domain-containing protein 1 (RhoBTB1)
      cl21455
      Location:1 → 87
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

    9. XM_028853335.1 → XP_028709168.1  rho-related BTB domain-containing protein 1 isoform X1

      UniProtKB/TrEMBL
      A0A8J8YGF6, F7FD59, G7N2E8, H9F5Y9
      Conserved Domains (4) summary
      cd01873
      Location:13 → 207
      RhoBTB; RhoBTB protein is an atypical member of the Rho family of small GTPases
      cd18355
      Location:248 → 460
      BTB1_POZ_RHOBTB1; first BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Rho-related BTB domain-containing protein 1 (RhoBTB1)
      cd18358
      Location:465 → 590
      BTB2_POZ_RHOBTB1; second BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Rho-related BTB domain-containing protein 1 (RhoBTB1)
      cd18530
      Location:593 → 692
      BACK_RHOBTB1; BACK (BTB and C-terminal Kelch) domain found in Rho-related BTB domain-containing protein 1 (RhoBTB1)

    10. XM_028853340.1 → XP_028709173.1  rho-related BTB domain-containing protein 1 isoform X1

      UniProtKB/TrEMBL
      A0A8J8YGF6, F7FD59, G7N2E8, H9F5Y9
      Conserved Domains (4) summary
      cd01873
      Location:13 → 207
      RhoBTB; RhoBTB protein is an atypical member of the Rho family of small GTPases
      cd18355
      Location:248 → 460
      BTB1_POZ_RHOBTB1; first BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Rho-related BTB domain-containing protein 1 (RhoBTB1)
      cd18358
      Location:465 → 590
      BTB2_POZ_RHOBTB1; second BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Rho-related BTB domain-containing protein 1 (RhoBTB1)
      cd18530
      Location:593 → 692
      BACK_RHOBTB1; BACK (BTB and C-terminal Kelch) domain found in Rho-related BTB domain-containing protein 1 (RhoBTB1)

    11. XM_028853334.1 → XP_028709167.1  rho-related BTB domain-containing protein 1 isoform X1

      UniProtKB/TrEMBL
      A0A8J8YGF6, F7FD59, G7N2E8, H9F5Y9
      Conserved Domains (4) summary
      cd01873
      Location:13 → 207
      RhoBTB; RhoBTB protein is an atypical member of the Rho family of small GTPases
      cd18355
      Location:248 → 460
      BTB1_POZ_RHOBTB1; first BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Rho-related BTB domain-containing protein 1 (RhoBTB1)
      cd18358
      Location:465 → 590
      BTB2_POZ_RHOBTB1; second BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Rho-related BTB domain-containing protein 1 (RhoBTB1)
      cd18530
      Location:593 → 692
      BACK_RHOBTB1; BACK (BTB and C-terminal Kelch) domain found in Rho-related BTB domain-containing protein 1 (RhoBTB1)

    12. XM_028853348.1 → XP_028709181.1  rho-related BTB domain-containing protein 1 isoform X2

      UniProtKB/TrEMBL
      H9F5Y9
      Conserved Domains (4) summary
      cd18355
      Location:128 → 340
      BTB1_POZ_RHOBTB1; first BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Rho-related BTB domain-containing protein 1 (RhoBTB1)
      cd18358
      Location:345 → 470
      BTB2_POZ_RHOBTB1; second BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Rho-related BTB domain-containing protein 1 (RhoBTB1)
      cd18530
      Location:473 → 572
      BACK_RHOBTB1; BACK (BTB and C-terminal Kelch) domain found in Rho-related BTB domain-containing protein 1 (RhoBTB1)
      cl21455
      Location:1 → 87
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

    13. XM_028853339.1 → XP_028709172.1  rho-related BTB domain-containing protein 1 isoform X1

      UniProtKB/TrEMBL
      A0A8J8YGF6, F7FD59, G7N2E8, H9F5Y9
      Conserved Domains (4) summary
      cd01873
      Location:13 → 207
      RhoBTB; RhoBTB protein is an atypical member of the Rho family of small GTPases
      cd18355
      Location:248 → 460
      BTB1_POZ_RHOBTB1; first BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Rho-related BTB domain-containing protein 1 (RhoBTB1)
      cd18358
      Location:465 → 590
      BTB2_POZ_RHOBTB1; second BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Rho-related BTB domain-containing protein 1 (RhoBTB1)
      cd18530
      Location:593 → 692
      BACK_RHOBTB1; BACK (BTB and C-terminal Kelch) domain found in Rho-related BTB domain-containing protein 1 (RhoBTB1)

    14. XM_028853342.1 → XP_028709175.1  rho-related BTB domain-containing protein 1 isoform X1

      UniProtKB/TrEMBL
      A0A8J8YGF6, F7FD59, G7N2E8, H9F5Y9
      Related
      ENSMMUP00000076826.1, ENSMMUT00000086109.1
      Conserved Domains (4) summary
      cd01873
      Location:13 → 207
      RhoBTB; RhoBTB protein is an atypical member of the Rho family of small GTPases
      cd18355
      Location:248 → 460
      BTB1_POZ_RHOBTB1; first BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Rho-related BTB domain-containing protein 1 (RhoBTB1)
      cd18358
      Location:465 → 590
      BTB2_POZ_RHOBTB1; second BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Rho-related BTB domain-containing protein 1 (RhoBTB1)
      cd18530
      Location:593 → 692
      BACK_RHOBTB1; BACK (BTB and C-terminal Kelch) domain found in Rho-related BTB domain-containing protein 1 (RhoBTB1)

    15. XM_028853341.1 → XP_028709174.1  rho-related BTB domain-containing protein 1 isoform X1

      UniProtKB/TrEMBL
      A0A8J8YGF6, F7FD59, G7N2E8, H9F5Y9
      Conserved Domains (4) summary
      cd01873
      Location:13 → 207
      RhoBTB; RhoBTB protein is an atypical member of the Rho family of small GTPases
      cd18355
      Location:248 → 460
      BTB1_POZ_RHOBTB1; first BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Rho-related BTB domain-containing protein 1 (RhoBTB1)
      cd18358
      Location:465 → 590
      BTB2_POZ_RHOBTB1; second BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Rho-related BTB domain-containing protein 1 (RhoBTB1)
      cd18530
      Location:593 → 692
      BACK_RHOBTB1; BACK (BTB and C-terminal Kelch) domain found in Rho-related BTB domain-containing protein 1 (RhoBTB1)

    16. XM_028853344.1 → XP_028709177.1  rho-related BTB domain-containing protein 1 isoform X1

      UniProtKB/TrEMBL
      A0A8J8YGF6, F7FD59, G7N2E8, H9F5Y9
      Conserved Domains (4) summary
      cd01873
      Location:13 → 207
      RhoBTB; RhoBTB protein is an atypical member of the Rho family of small GTPases
      cd18355
      Location:248 → 460
      BTB1_POZ_RHOBTB1; first BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Rho-related BTB domain-containing protein 1 (RhoBTB1)
      cd18358
      Location:465 → 590
      BTB2_POZ_RHOBTB1; second BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Rho-related BTB domain-containing protein 1 (RhoBTB1)
      cd18530
      Location:593 → 692
      BACK_RHOBTB1; BACK (BTB and C-terminal Kelch) domain found in Rho-related BTB domain-containing protein 1 (RhoBTB1)
    Nucleotide Protein
    Heading Accession and Version

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