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    KPNA3 karyopherin subunit alpha 3 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 706925, updated on 17-Aug-2024

    Summary

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    Official Symbol
    KPNA3provided by VGNC
    Official Full Name
    karyopherin subunit alpha 3provided by VGNC
    Primary source
    VGNC:VGNC:74200
    See related
    Ensembl:ENSMMUG00000020572
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See KPNA3 in Genome Data Viewer
    Location:
    chromosome: 17
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 17 NC_041770.1 (28155553..28252720, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 17 NC_027909.1 (29007185..29103991, complement)

    Chromosome 17 - NC_041770.1Genomic Context describing neighboring genes Neighboring gene ADP ribosylation factor like GTPase 11 Neighboring gene EBP like Neighboring gene uncharacterized LOC114673462 Neighboring gene uncharacterized LOC106994275 Neighboring gene uncharacterized LOC114673463

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables nuclear import signal receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables nuclear localization sequence binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in NLS-bearing protein import into nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    importin subunit alpha-4
    Names
    importin subunit alpha-3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041770.1 Reference Mmul_10 Primary Assembly

      Range
      28155553..28252720 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015121089.2 → XP_014976575.1  importin subunit alpha-4 isoform X3

      UniProtKB/TrEMBL
      A0A5F7ZFC5, A0A5F8A5V2
      Related
      ENSMMUP00000072292.1, ENSMMUT00000083892.1
      Conserved Domains (4) summary
      COG5064
      Location:2 → 477
      SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
      cd00020
      Location:108 → 229
      ARM; Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin, ...
      pfam01749
      Location:9 → 93
      IBB; Importin beta binding domain
      sd00043
      Location:109 → 142
      ARM; armadillo repeat [structural motif]

    2. XM_015121088.2 → XP_014976574.1  importin subunit alpha-4 isoform X1

      UniProtKB/TrEMBL
      A0A5F7ZFC5, F7D176, H9FU81
      Related
      ENSMMUP00000027086.3, ENSMMUT00000028944.4
      Conserved Domains (2) summary
      COG5064
      Location:2 → 521
      SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
      sd00043
      Location:244 → 269
      ARM; armadillo repeat [structural motif]

    3. XM_028837582.1 → XP_028693415.1  importin subunit alpha-4 isoform X2

      UniProtKB/TrEMBL
      A0A5F7ZFC5
      Conserved Domains (2) summary
      COG5064
      Location:1 → 497
      SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
      sd00043
      Location:220 → 245
      ARM; armadillo repeat [structural motif]
    Nucleotide Protein
    Heading Accession and Version

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