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    GHV growth hormone variant [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 700885, updated on 9-Nov-2023

    Summary

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    Gene symbol
    GHV
    Gene description
    growth hormone variant
    See related
    Ensembl:ENSMMUG00000039847
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Also known as
    GH2; GH-2; GH-V; GHB4
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    Genomic context

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    See GHV in Genome Data Viewer
    Location:
    chromosome: 16
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 16 NC_041769.1 (60456824..60458746, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) Unplaced Scaffold NW_014955106.1 (87..1107, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) Unplaced Scaffold NW_014974500.1 (20537..21118, complement)

    Chromosome 16 - NC_041769.1Genomic Context describing neighboring genes Neighboring gene growth hormone variant-like Neighboring gene somatotropin-like Neighboring gene chorionic somatomammotropin-1 Neighboring gene growth hormone 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Ancient origin of placental expression in the growth hormone genes of anthropoid primates. Papper Z, et al. Proc Natl Acad Sci U S A, 2009 Oct 6. PMID 19805162, Free PMC Article
    2. Cloning of four growth hormone/chorionic somatomammotropin-related complementary deoxyribonucleic acids differentially expressed during pregnancy in the rhesus monkey placenta. Golos TG, et al. Endocrinology, 1993 Oct. PMID 8404617
    3. Gene conversions in the growth hormone gene family of primates: stronger homogenizing effects in the Hominidae lineage. Petronella N, et al. Genomics, 2011 Sep. PMID 21683133
    4. Growth hormone-related genes from baboon (Papio hamadryas): Characterization, placental expression and evolutionary aspects. Rodríguez-Sánchez IP, et al. Gene, 2010 Jan 15. PMID 19651193, Free PMC Article
    5. Growth hormone locus expands and diverges after the separation of New and Old World Monkeys. González Alvarez R, et al. Gene, 2006 Sep 15. PMID 16872758

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables growth hormone receptor binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables hormone activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in animal organ development IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in growth hormone receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of growth IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of receptor signaling pathway via JAK-STAT IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of tyrosine phosphorylation of STAT protein IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in response to nutrient levels IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in extracellular space IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    growth hormone variant
    Names
    growth hormone 2
    growth hormone B4
    placenta-specific growth hormone

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001042739.1 → NP_001036204.1  growth hormone variant precursor

      See identical proteins and their annotated locations for NP_001036204.1

      Status: PROVISIONAL

      Source sequence(s)
      L16555
      UniProtKB/TrEMBL
      A0A0M6L0V8, A0A5F7ZB15, Q1L7U8
      Related
      ENSMMUP00000062761.1, ENSMMUT00000084681.1
      Conserved Domains (1) summary
      cd10285
      Location:35 → 215
      somatotropin_like; Somatotropin or growth hormone (GH), placental lactogen, and related pituitary gland hormones

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041769.1 Reference Mmul_10 Primary Assembly

      Range
      60456824..60458746 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028835510.1 → XP_028691343.1  growth hormone variant isoform X1

      UniProtKB/TrEMBL
      A0A0M6L0V8, Q1L7U8
      Conserved Domains (1) summary
      cd10285
      Location:35 → 246
      somatotropin_like; Somatotropin or growth hormone (GH), placental lactogen, and related pituitary gland hormones
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q07370.1 GenPept UniProtKB/Swiss-Prot:Q07370

    Gene LinkOut

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    Molecular Biology Databases
    Research Materials