Susd2 sushi domain containing 2 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Susd2provided by RGD
Official Full Name: sushi domain containing 2provided by RGD
Primary source: RGD:1308595
See related: EnsemblRapid:ENSRNOG00000033389 AllianceGenome:RGD:1308595
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to be involved in negative regulation of cell cycle G1/S phase transition and negative regulation of cell division. Predicted to be located in plasma membrane. Predicted to be active in extracellular space. Orthologous to human SUSD2 (sushi domain containing 2). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Kidney (RPKM 423.0), Spleen (RPKM 95.7) and 4 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 20p12

Exon count:: 15

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	20	NC_086038.1 (13016960..13024264)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	20	NC_051355.1 (13017516..13024820)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	20	NC_005119.4 (13965098..13972547)

Chromosome 20 - NC_086038.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Susd2 alters axon and dendritic outgrowth, regulates excitatory synapse numbers.
Title: The Susd2 protein regulates neurite growth and excitatory synaptic density in hippocampal cultures.

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by RGD

Process	Evidence Code	Pubs
involved_in negative regulation of cell cycle G1/S phase transition	ISO Inferred from Sequence Orthology more info
involved_in negative regulation of cell division	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
is_active_in extracellular space	IBA Inferred from Biological aspect of Ancestor more info
located_in membrane	IEA Inferred from Electronic Annotation more info
located_in plasma membrane	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: sushi domain-containing protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001414913.1 → NP_001401842.1 sushi domain-containing protein 2 precursor

Status: VALIDATED

Source sequence(s)

JAXUCZ010000020

UniProtKB/TrEMBL

A0A0G2K0Q8, A6JKH9, D3ZEV8

Related

ENSRNOP00000071546.2, ENSRNOT00000079996.4

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

NC_086038.1 Reference GRCr8

Range

13016960..13024264

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GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

NM_001106381.1: Suppressed sequence

Description

NM_001106381.1: This RefSeq was removed because currently there is insufficient support for the transcript and the protein.