Odf4 outer dense fiber of sperm tails 4 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Odf4provided by MGI
Official Full Name: outer dense fiber of sperm tails 4provided by MGI
Primary source: MGI:MGI:2182079
See related: Ensembl:ENSMUSG00000032921 AllianceGenome:MGI:2182079
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: Oppo1
Summary: Predicted to be involved in cell differentiation and spermatogenesis. Located in outer dense fiber. Is expressed in ductus deferens; epididymis; prostate gland; and testis. Orthologous to human ODF4 (outer dense fiber of sperm tails 4). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Restricted expression toward testis adult (RPKM 131.5) See more
Orthologs: human all
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Genomic context

Location:: 11 B3; 11 42.19 cM

Exon count:: 5

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	11	NC_000077.7 (68812661..68817907, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	11	NC_000077.6 (68921835..68927081, complement)

Chromosome 11 - NC_000077.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

The association of ODF4 with AK1 and AK2 in mice is essential for fertility through its contribution to flagellar shape.
Title: The association of ODF4 with AK1 and AK2 in mice is essential for fertility through its contribution to flagellar shape.
oppo 1 plays an important role in sperm tail structure and/or sperm movement
Title: Molecular cloning and characterization of oppo 1: a haploid germ cell-specific complementary DNA encoding sperm tail protein.

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Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Endonuclease-mediated (1)
Targeted (2)

General gene information

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Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables molecular_function	ND No biological Data available more info

Process	Evidence Code	Pubs
involved_in biological_process	ND No biological Data available more info
involved_in cell differentiation	IEA Inferred from Electronic Annotation more info
involved_in spermatogenesis	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info
located_in motile cilium	IDA Inferred from Direct Assay more info	PubMed
located_in outer dense fiber	IDA Inferred from Direct Assay more info	PubMed
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: outer dense fiber protein 4

Names: outer dense fiber of sperm tails protein 4; testis-specific protein oppo 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.