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    Rnase13 ribonuclease, RNase A family, 13 (non-active) [ Mus musculus (house mouse) ]

    Gene ID: 497071, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Rnase13provided by MGI
    Official Full Name
    ribonuclease, RNase A family, 13 (non-active)provided by MGI
    Primary source
    MGI:MGI:3528592
    See related
    Ensembl:ENSMUSG00000068392 AllianceGenome:MGI:3528592
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Summary
    Predicted to enable nucleic acid binding activity. Predicted to be involved in defense response to Gram-positive bacterium. Predicted to be located in extracellular region. Orthologous to human RNASE13 (ribonuclease A family member 13 (inactive)). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Restricted expression toward genital fat pad adult (RPKM 122.4) See more
    Orthologs
    human all
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    Genomic context

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    See Rnase13 in Genome Data Viewer
    Location:
    14 C2; 14 26.73 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 14 NC_000080.7 (52158817..52160734, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 14 NC_000080.6 (51921365..51923277, complement)

    Chromosome 14 - NC_000080.7Genomic Context describing neighboring genes Neighboring gene N-myc downstream regulated gene 2 Neighboring gene tubulin polymerization-promoting protein family member 2 Neighboring gene chaperonin containing Tcp1, subunit 6a (zeta) pseudogene Neighboring gene Rho guanine nucleotide exchange factor 40 Neighboring gene predicted gene, 16617

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Nine genes abundantly expressed in the epididymis are not essential for male fecundity in mice. Noda T, et al. Andrology, 2019 Sep. PMID 30927342, Free PMC Article
    2. The ribonuclease A superfamily of mammals and birds: identifying new members and tracing evolutionary histories. Cho S, et al. Genomics, 2005 Feb. PMID 15676279
    3. Genetic determinants of micronucleus formation in vivo. Adams DJ, et al. Nature, 2024 Mar. PMID 38355793, Free PMC Article
    4. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
    5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    General gene information

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    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    NOT enables RNA nuclease activity IKR
    Inferred from Key Residues
    more info
    		 PubMed 
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in defense response to Gram-positive bacterium IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    probable inactive ribonuclease-like protein 13
    Names
    pancreatic ribonuclease
    ribonuclease-like protein 13

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001011687.3 → NP_001011687.1  probable inactive ribonuclease-like protein 13 precursor

      See identical proteins and their annotated locations for NP_001011687.1

      Status: VALIDATED

      Source sequence(s)
      AC125087
      Consensus CDS
      CCDS27048.1
      UniProtKB/Swiss-Prot
      Q5GAM7
      Conserved Domains (1) summary
      pfam00074
      Location:27 → 150
      RnaseA; Pancreatic ribonuclease

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000080.7 Reference GRCm39 C57BL/6J

      Range
      52158817..52160734 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006519218.1 → XP_006519281.1  probable inactive ribonuclease-like protein 13 isoform X1

      See identical proteins and their annotated locations for XP_006519281.1

      UniProtKB/Swiss-Prot
      Q5GAM7
      Conserved Domains (1) summary
      pfam00074
      Location:27 → 150
      RnaseA; Pancreatic ribonuclease

    2. XM_017316076.2 → XP_017171565.1  probable inactive ribonuclease-like protein 13 isoform X1

      UniProtKB/Swiss-Prot
      Q5GAM7
      Related
      ENSMUSP00000087203.3, ENSMUST00000089771.4
      Conserved Domains (1) summary
      pfam00074
      Location:27 → 150
      RnaseA; Pancreatic ribonuclease
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q5GAM7.1 GenPept UniProtKB/Swiss-Prot:Q5GAM7

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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