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    Ceacam5 CEA cell adhesion molecule 5 [ Mus musculus (house mouse) ]

    Gene ID: 73250, updated on 9-Dec-2024

    Summary

    Official Symbol
    Ceacam5provided by MGI
    Official Full Name
    CEA cell adhesion molecule 5provided by MGI
    Primary source
    MGI:MGI:1920500
    See related
    Ensembl:ENSMUSG00000008789 AllianceGenome:MGI:1920500
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Psg30; 1600029H12Rik
    Summary
    Predicted to enable identical protein binding activity. Predicted to be involved in several processes, including T cell activation; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules; and homophilic cell adhesion via plasma membrane adhesion molecules. Predicted to be located in apical plasma membrane; cell surface; and cytosol. Predicted to be active in external side of plasma membrane. Orthologous to human CEACAM7 (CEA cell adhesion molecule 7). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Restricted expression toward placenta adult (RPKM 159.5) See more
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    Genomic context

    See Ceacam5 in Genome Data Viewer
    Location:
    7 A2; 7 9.15 cM
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (17447141..17495046)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (17713216..17761121)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 45973 Neighboring gene pregnancy specific beta-1-glycoprotein, pseudogene 1 Neighboring gene STARR-seq mESC enhancer starr_18156 Neighboring gene peptidylprolyl isomerase A pseudogene 7_184.1 Neighboring gene CEA cell adhesion molecule 14

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (4) 

    Interactions

    General gene information

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables identical protein binding  
    enables molecular_function  
    Process Evidence Code Pubs
    involved_in T cell activation  
    involved_in apoptotic process  
    involved_in biological_process  
    involved_in heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules  
    involved_in homophilic cell adhesion via plasma membrane adhesion molecules  
    involved_in immune response  
    Component Evidence Code Pubs
    located_in apical plasma membrane  
    located_in apical plasma membrane  
    located_in cell surface  
    is_active_in cellular_component  
    located_in cytosol  
    is_active_in external side of plasma membrane  
    located_in membrane  
    located_in plasma membrane  
    located_in side of membrane  

    General protein information

    Preferred Names
    cell adhesion molecule CEACAM5; carcinoembryonic antigen-related cell adhesion molecule 5
    Names
    pregnancy-specific glycoprotein 30

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_028480.2NP_082756.1  cell adhesion molecule CEACAM5 precursor

      See identical proteins and their annotated locations for NP_082756.1

      Status: PROVISIONAL

      Source sequence(s)
      AK145976
      Consensus CDS
      CCDS20863.1
      UniProtKB/Swiss-Prot
      Q3UKK2
      Related
      ENSMUSP00000080582.7, ENSMUST00000081907.8
      Conserved Domains (4) summary
      cd05774
      Location:393496
      Ig_CEACAM_D1; First immunoglobulin (Ig)-like domain of carcinoembryonic antigen (CEA) related cell adhesion molecule (CEACAM)
      smart00408
      Location:872933
      IGc2; Immunoglobulin C-2 Type
      smart00410
      Location:865944
      IG_like; Immunoglobulin like
      cl11960
      Location:510614
      Ig; Immunoglobulin domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      17447141..17495046
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006540389.3XP_006540452.1  carcinoembryonic antigen-related cell adhesion molecule 5 isoform X1

      Conserved Domains (3) summary
      smart00408
      Location:754815
      IGc2; Immunoglobulin C-2 Type
      cd05774
      Location:630733
      Ig_CEACAM_D1; First immunoglobulin (Ig)-like domain of carcinoembryonic antigen (CEA) related cell adhesion molecule (CEACAM)
      cl11960
      Location:510614
      Ig; Immunoglobulin domain
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