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    Or52a24 olfactory receptor family 52 subfamily A member 24 [ Mus musculus (house mouse) ]

    Gene ID: 259159, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Or52a24provided by MGI
    Official Full Name
    olfactory receptor family 52 subfamily A member 24provided by MGI
    Primary source
    MGI:MGI:3030462
    See related
    Ensembl:ENSMUSG00000096516 AllianceGenome:MGI:3030462
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    MOR22-1; Olfr628; MOR22-4P; Olfr1526-ps1
    Summary
    Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]
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    Genomic context

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    See Or52a24 in Genome Data Viewer
    Location:
    7 E3; 7 54.85 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (103381135..103382085)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (103731928..103732878)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene olfactory receptor family 52 subfamily AE member 6, pseudogene 1 Neighboring gene STARR-seq mESC enhancer starr_19726 Neighboring gene olfactory receptor family 52 subfamily A member 20 Neighboring gene olfactory receptor family 52 subfamily AE member 9 Neighboring gene olfactory receptor family 51 subfamily L member 4

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Comparative structural and functional analysis of the olfactory receptor genes flanking the human and mouse beta-globin gene clusters. Bulger M, et al. Proc Natl Acad Sci U S A, 2000 Dec 19. PMID 11121057, Free PMC Article
    2. A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome. Mural RJ, et al. Science, 2002 May 31. PMID 12040188
    3. The olfactory receptor gene superfamily of the mouse. Zhang X, et al. Nat Neurosci, 2002 Feb. PMID 11802173
    4. Different evolutionary processes shaped the mouse and human olfactory receptor gene families. Young JM, et al. Hum Mol Genet, 2002 Mar 1. PMID 11875048
    5. Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels. Young JM, et al. Genome Biol, 2003. PMID 14611657, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC129314, MGC129315

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables olfactory receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables olfactory receptor activity ISA
    Inferred from Sequence Alignment
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within G protein-coupled receptor signaling pathway ISA
    Inferred from Sequence Alignment
    more info
    		 PubMed 
    acts_upstream_of_or_within sensory perception of smell ISA
    Inferred from Sequence Alignment
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane ISA
    Inferred from Sequence Alignment
    more info
    		 PubMed 
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    olfactory receptor 628
    Names
    GA_x6K02T2PBJ9-6457667-6458617
    olfactory receptor 1526, pseudogene 1
    olfactory receptor MOR22-1
    olfactory receptor MOR22-4P

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_147097.2 → NP_667308.2  olfactory receptor 628

      Status: VALIDATED

      Source sequence(s)
      AC143329
      Consensus CDS
      CCDS52338.1
      UniProtKB/TrEMBL
      K7N6B2, Q9EQQ5
      Related
      ENSMUSP00000151622.2, ENSMUST00000218266.2
      Conserved Domains (2) summary
      pfam00001
      Location:43 → 295
      7tm_1; 7 transmembrane receptor (rhodopsin family)
      cl21561
      Location:33 → 310
      7tm_4; Olfactory receptor

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      103381135..103382085
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NG_002147.2: Suppressed sequence

      Description
      NG_002147.2: This RefSeq was permanently suppressed because it is now thought that this gene does encode a protein.
    Nucleotide Protein Strain
    Heading Accession and Version

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