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    GUCY2GP guanylate cyclase 2G, pseudogene [ Homo sapiens (human) ]

    Gene ID: 390003, updated on 4-Jan-2025

    Summary

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    Official Symbol
    GUCY2GPprovided by HGNC
    Official Full Name
    guanylate cyclase 2G, pseudogeneprovided by HGNC
    Primary source
    HGNC:HGNC:31863
    See related
    Ensembl:ENSG00000243316 AllianceGenome:HGNC:31863
    Gene type
    pseudo
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    GUCY2G
    Summary
    Predicted to enable guanylate cyclase activity. Predicted to be located in external side of plasma membrane. [provided by Alliance of Genome Resources, Jan 2025]
    Expression
    Low expression observed in reference dataset See more
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    Genomic context

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    See GUCY2GP in Genome Data Viewer
    Location:
    10q25.2
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 10 NC_000010.11 (112308178..112356595, complement)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 10 NC_060934.1 (113199175..113247598, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 10 NC_000010.10 (114067936..114116353, complement)

    Chromosome 10 - NC_000010.11Genomic Context describing neighboring genes Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2831 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4062 Neighboring gene glycerol-3-phosphate acyltransferase, mitochondrial Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:113999878-114000378 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr10:114048161-114048789 Neighboring gene Sharpr-MPRA regulatory region 2531 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2832 Neighboring gene microRNA 6715b Neighboring gene microRNA 6715a Neighboring gene tectorin beta Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:114135606-114136106 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:114136107-114136607 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2833 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2834 Neighboring gene acyl-CoA synthetase long chain family member 5 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4065 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4066 Neighboring gene Sharpr-MPRA regulatory region 13267 Neighboring gene zinc finger DHHC-type palmitoyltransferase 6 Neighboring gene vesicle transport through interaction with t-SNAREs 1A Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4067 Neighboring gene uncharacterized LOC124902503 Neighboring gene microRNA 4295

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Tissue-specific circular RNA induction during human fetal development
    • Description: 35 human fetal samples from 6 tissues (3 - 7 replicates per tissue) collected between 10 and 20 weeks gestational time were sequenced using Illumina TruSeq Stranded Total RNA
    • BioProject: PRJNA270632
    • Publication: PMID 26076956
    • Analysis date: Mon Apr 2 22:54:59 2018

    Bibliography

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    Related articles in PubMed

    1. Characterization of a novel cell-surface protein expressed on human sperm. Yang RB, et al. Hum Reprod, 2010 Jan. PMID 19828552
    2. Function and dysfunction of mammalian membrane guanylyl cyclase receptors: lessons from genetic mouse models and implications for human diseases. Kuhn M. Handb Exp Pharmacol, 2009. PMID 19089325
    3. Identification and analysis of unitary pseudogenes: historic and contemporary gene losses in humans and other primates. Zhang ZD, et al. Genome Biol, 2010. PMID 20210993, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Phenotypes

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    Review eQTL and phenotype association data in this region using PheGenI

    Variation

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    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    General gene information

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    Other Names

    • guanylate cyclase 2G homolog, pseudogene

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    RNA

    1. NR_028134.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL157786
      Related
      ENST00000479705.5

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000010.11 Reference GRCh38.p14 Primary Assembly

      Range
      112308178..112356595 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060934.1 Alternate T2T-CHM13v2.0

      Range
      113199175..113247598 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NG_009698.1: Suppressed sequence

      Description
      NG_009698.1: This RefSeq was permanently suppressed because it is now thought that this pseudogene is transcribed.
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Other Literature Sources
    Chemical Information
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    Research Materials