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    Dmac2 distal membrane arm assembly component 2 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 361520, updated on 3-Dec-2024

    Summary

    Official Symbol
    Dmac2provided by RGD
    Official Full Name
    distal membrane arm assembly component 2provided by RGD
    Primary source
    RGD:1549698
    See related
    EnsemblRapid:ENSRNOG00000020596 AllianceGenome:RGD:1549698
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Atp5sl
    Summary
    Predicted to be involved in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process and mitochondrial respiratory chain complex I assembly. Predicted to be located in mitochondrion. Predicted to be part of SCF ubiquitin ligase complex. Orthologous to human DMAC2 (distal membrane arm assembly component 2). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Heart (RPKM 172.2), Kidney (RPKM 140.6) and 9 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Dmac2 in Genome Data Viewer
    Location:
    1q21
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (90250262..90262592)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (81128760..81134810)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (82413171..82419157)

    Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC120096895 Neighboring gene C-X-C motif chemokine ligand 17 Neighboring gene uncharacterized LOC102549342 Neighboring gene CEA cell adhesion molecule 1 Neighboring gene glutamate-rich 4 Neighboring gene UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8 Neighboring gene branched chain keto acid dehydrogenase E1 subunit alpha Neighboring gene exosome component 5

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General protein information

    Preferred Names
    distal membrane-arm assembly complex protein 2
    Names
    ATP synthase subunit s-like protein
    ATP5S-like
    distal membrane arm assembly complex 2

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001009705.1NP_001009705.1  distal membrane-arm assembly complex protein 2

      See identical proteins and their annotated locations for NP_001009705.1

      Status: PROVISIONAL

      Source sequence(s)
      BC088283
      UniProtKB/Swiss-Prot
      Q5I0I4
      UniProtKB/TrEMBL
      A6J970, A6J971
      Related
      ENSRNOP00000027960.6, ENSRNOT00000027960.8
      Conserved Domains (1) summary
      sd00034
      Location:147172
      LRR_AMN1; leucine-rich repeat [structural motif]

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086019.1 Reference GRCr8

      Range
      90250262..90262592
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063266369.1XP_063122439.1  distal membrane-arm assembly complex protein 2 isoform X3

      UniProtKB/TrEMBL
      A6J970
    2. XM_063266378.1XP_063122448.1  distal membrane-arm assembly complex protein 2 isoform X3

      UniProtKB/TrEMBL
      A6J970
    3. XM_039081795.2XP_038937723.1  distal membrane-arm assembly complex protein 2 isoform X6

    4. XM_039081785.2XP_038937713.1  distal membrane-arm assembly complex protein 2 isoform X5

    5. XM_017589351.3XP_017444840.1  distal membrane-arm assembly complex protein 2 isoform X1

      UniProtKB/TrEMBL
      A6J970
      Related
      ENSRNOP00000102684.1, ENSRNOT00000156432.1
    6. XM_063266374.1XP_063122444.1  distal membrane-arm assembly complex protein 2 isoform X4

      UniProtKB/TrEMBL
      A6J970
    7. XM_017589352.3XP_017444841.1  distal membrane-arm assembly complex protein 2 isoform X2

      UniProtKB/TrEMBL
      A6J970