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    Slc30a9 solute carrier family 30 member 9 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 498358, updated on 27-Nov-2024

    Summary

    Official Symbol
    Slc30a9provided by RGD
    Official Full Name
    solute carrier family 30 member 9provided by RGD
    Primary source
    RGD:1593180
    See related
    EnsemblRapid:ENSRNOG00000002246 AllianceGenome:RGD:1593180
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable several functions, including nuclear receptor binding activity; nuclear receptor coactivator activity; and zinc ion transmembrane transporter activity. Predicted to be involved in intracellular zinc ion homeostasis; regulation of mitochondrion organization; and zinc ion transport. Predicted to act upstream of or within positive regulation of transcription by RNA polymerase II. Predicted to be located in several cellular components, including cytoplasmic vesicle; cytoskeleton; and mitochondrial membrane. Predicted to be active in endoplasmic reticulum. Orthologous to human SLC30A9 (solute carrier family 30 member 9). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Brain (RPKM 314.4), Kidney (RPKM 228.5) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Slc30a9 in Genome Data Viewer
    Location:
    14p11
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 14 NC_086032.1 (41170164..41224861, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 14 NC_051349.1 (40816284..40870992, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 14 NC_005113.4 (42464814..42519760, complement)

    Chromosome 14 - NC_086032.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC108352745 Neighboring gene BEN domain containing 4 Neighboring gene glyceraldehyde-3-phosphate dehydrogenase-like Neighboring gene transmembrane protein 33 Neighboring gene uncharacterized LOC134481844

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables antiporter activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables chromatin binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables nuclear receptor binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables nuclear receptor coactivator activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables zinc ion transmembrane transporter activity ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in intracellular zinc ion homeostasis IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in intracellular zinc ion homeostasis ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within positive regulation of transcription by RNA polymerase II ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of mitochondrion organization ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in zinc ion transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in zinc ion transport IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in zinc ion transport ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in cytoplasmic vesicle ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytoskeleton ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in endoplasmic reticulum IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in endoplasmic reticulum ISO
    Inferred from Sequence Orthology
    more info
     
    located_in mitochondrial membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in mitochondrion ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    proton-coupled zinc antiporter SLC30A9, mitochondrial
    Names
    solute carrier family 30 (zinc transporter), member 9
    zinc transporter 9

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001109088.1NP_001102558.1  proton-coupled zinc antiporter SLC30A9, mitochondrial

      See identical proteins and their annotated locations for NP_001102558.1

      Status: PROVISIONAL

      Source sequence(s)
      CH473981
      UniProtKB/TrEMBL
      A0A8I5ZUD8, A0A8I6AXK2, A6JDA5
      Related
      ENSRNOP00000082378.1, ENSRNOT00000100697.2
      Conserved Domains (2) summary
      TIGR00598
      Location:123208
      rad14; DNA repair protein
      pfam01545
      Location:250449
      Cation_efflux; Cation efflux family

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086032.1 Reference GRCr8

      Range
      41170164..41224861 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006250963.4XP_006251025.1  proton-coupled zinc antiporter SLC30A9, mitochondrial isoform X1

      UniProtKB/TrEMBL
      A0A8I6AXK2
      Related
      ENSRNOP00000093811.1, ENSRNOT00000097270.2
      Conserved Domains (2) summary
      TIGR00598
      Location:122207
      rad14; DNA repair protein
      pfam01545
      Location:249448
      Cation_efflux; Cation efflux family