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    Mtarc1 mitochondrial amidoxime reducing component 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 690745, updated on 3-Dec-2024

    Summary

    Official Symbol
    Mtarc1provided by RGD
    Official Full Name
    mitochondrial amidoxime reducing component 1provided by RGD
    Primary source
    RGD:1592219
    See related
    EnsemblRapid:ENSRNOG00000037850 AllianceGenome:RGD:1592219
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Marc1; Mosc1
    Summary
    Predicted to enable molybdenum ion binding activity; molybdopterin cofactor binding activity; and oxidoreductase activity, acting on other nitrogenous compounds as donors. Predicted to contribute to nitrite reductase (NO-forming) activity. Predicted to be involved in cellular detoxification of nitrogen compound; nitrate metabolic process; and nitric oxide biosynthetic process. Predicted to be located in mitochondrion. Predicted to be part of nitric-oxide synthase complex. Orthologous to human MTARC1 (mitochondrial amidoxime reducing component 1). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Liver (RPKM 730.7), Kidney (RPKM 188.6) and 2 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Mtarc1 in Genome Data Viewer
    Location:
    13q26
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 13 NC_086031.1 (98854235..98894208, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 13 NC_051348.1 (96324377..96362677, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 13 NC_005112.4 (102693679..102724120, complement)

    Chromosome 13 - NC_086031.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC120096339 Neighboring gene H2.0-like homeobox Neighboring gene uncharacterized LOC134481538 Neighboring gene mitochondrial amidoxime reducing component 2 Neighboring gene similar to human chromosome 1 open reading frame 115

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables molybdenum ion binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables molybdopterin cofactor binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables nitrate reductase activity ISO
    Inferred from Sequence Orthology
    more info
     
    contributes_to nitrite reductase (NO-forming) activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables nitrite reductase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables oxidoreductase activity, acting on other nitrogenous compounds as donors ISO
    Inferred from Sequence Orthology
    more info
     
    enables pyridoxal phosphate binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in cellular detoxification of nitrogen compound ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in nitrate metabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in nitric oxide biosynthetic process ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in mitochondrion ISO
    Inferred from Sequence Orthology
    more info
     
    part_of nitric-oxide synthase complex ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    mitochondrial amidoxime-reducing component 1
    Names
    MOCO sulphurase C-terminal domain containing 1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001100811.1NP_001094281.1  mitochondrial amidoxime-reducing component 1

      See identical proteins and their annotated locations for NP_001094281.1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000013
      UniProtKB/TrEMBL
      A6JGP5, D3Z900, G3V6I4
      Related
      ENSRNOP00000034963.6, ENSRNOT00000029439.8
      Conserved Domains (3) summary
      COG3217
      Location:60339
      YcbX; Uncharacterized conserved protein YcbX, contains MOSC and Fe-S domains [General function prediction only]
      pfam03473
      Location:207336
      MOSC; MOSC domain
      pfam03476
      Location:58179
      MOSC_N; MOSC N-terminal beta barrel domain

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086031.1 Reference GRCr8

      Range
      98854235..98894208 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039091110.2XP_038947038.1  mitochondrial amidoxime-reducing component 1 isoform X2

      UniProtKB/TrEMBL
      A6JGP6
      Conserved Domains (1) summary
      COG3217
      Location:60299
      YcbX; Uncharacterized conserved protein YcbX, contains MOSC and Fe-S domains [General function prediction only]
    2. XM_063272629.1XP_063128699.1  mitochondrial amidoxime-reducing component 1 isoform X1

      UniProtKB/TrEMBL
      A6JGP6