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    Zyg11b zyg-11 family member B, cell cycle regulator [ Rattus norvegicus (Norway rat) ]

    Gene ID: 362559, updated on 27-Nov-2024

    Summary

    Official Symbol
    Zyg11bprovided by RGD
    Official Full Name
    zyg-11 family member B, cell cycle regulatorprovided by RGD
    Primary source
    RGD:1307814
    See related
    EnsemblRapid:ENSRNOG00000010859 AllianceGenome:RGD:1307814
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1307814
    Summary
    Predicted to be involved in positive regulation of proteasomal ubiquitin-dependent protein catabolic process and protein quality control for misfolded or incompletely synthesized proteins. Predicted to be part of Cul2-RING ubiquitin ligase complex. Orthologous to human ZYG11B (zyg-11 family member B, cell cycle regulator). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Muscle (RPKM 483.4), Brain (RPKM 225.5) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Zyg11b in Genome Data Viewer
    Location:
    5q34
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 5 NC_086023.1 (128214293..128271446, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 5 NC_051340.1 (122985548..123042735, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 5 NC_005104.4 (127844062..127878792, complement)

    Chromosome 5 - NC_086023.1Genomic Context describing neighboring genes Neighboring gene enoyl CoA hydratase domain containing 2 Neighboring gene zyg-11 family member A, cell cycle regulator Neighboring gene basic transcription factor 3, pseudogene 13 Neighboring gene cytochrome c oxidase assembly factor 7 Neighboring gene shisa like 2A Neighboring gene terminal uridylyl transferase 4

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General protein information

    Preferred Names
    protein zyg-11 homolog B
    Names
    zyg-11 homolog B
    zyg-ll homolog B

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001426994.1NP_001413923.1  protein zyg-11 homolog B

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000005
      UniProtKB/TrEMBL
      F1M8P2
      Related
      ENSRNOP00000014436.7, ENSRNOT00000014436.9

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086023.1 Reference GRCr8

      Range
      128214293..128271446 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)