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    Mageb16 MAGE family member B16 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 317274, updated on 27-Nov-2024

    Summary

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    Official Symbol
    Mageb16provided by RGD
    Official Full Name
    MAGE family member B16provided by RGD
    Primary source
    RGD:1562365
    See related
    EnsemblRapid:ENSRNOG00000029408 AllianceGenome:RGD:1562365
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Snca
    Summary
    Predicted to be involved in negative regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Orthologous to human MAGEB16 (MAGE family member B16). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Restricted expression toward (RPKM 38.7) See more
    Orthologs
    human mouse all
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    Genomic context

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    See Mageb16 in Genome Data Viewer
    Location:
    Xq21
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) X NC_086039.1 (47580752..47665173, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) X NC_051356.1 (43693205..43725664, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) X NC_005120.4 (46977655..47026377, complement)

    Chromosome X - NC_086039.1Genomic Context describing neighboring genes Neighboring gene ubiquitin-conjugating enzyme E2L 3, pseudogene 2 Neighboring gene cilia and flagella associated protein 47 Neighboring gene transfer RNA serine (anticodon AGA) 25 Neighboring gene heterogeneous nuclear ribonucleoprotein A1-like Neighboring gene serine and arginine rich splicing factor 10, pseudogene 3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in negative regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    melanoma-associated antigen B16
    Names
    MAGE-B16 antigen
    melanoma antigen family B, 16

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001025013.1 → NP_001020184.1  melanoma-associated antigen B16

      See identical proteins and their annotated locations for NP_001020184.1

      Status: PROVISIONAL

      Source sequence(s)
      BC079208
      UniProtKB/Swiss-Prot
      Q6AY37
      UniProtKB/TrEMBL
      M0R5A2
      Related
      ENSRNOP00000097562.1, ENSRNOT00000116863.2
      Conserved Domains (2) summary
      pfam01454
      Location:150 → 300
      MAGE; MAGE family
      pfam12440
      Location:3 → 99
      MAGE_N; Melanoma associated antigen family N terminal

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086039.1 Reference GRCr8

      Range
      47580752..47665173 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063280034.1 → XP_063136104.1  melanoma-associated antigen B16 isoform X1

      UniProtKB/Swiss-Prot
      Q6AY37
      Related
      ENSRNOP00000103351.1, ENSRNOT00000161603.1

    2. XM_063280035.1 → XP_063136105.1  melanoma-associated antigen B16 isoform X1

      UniProtKB/Swiss-Prot
      Q6AY37
      Related
      ENSRNOP00000064565.2, ENSRNOT00000042568.6

    3. XM_063280033.1 → XP_063136103.1  melanoma-associated antigen B16 isoform X1

      UniProtKB/Swiss-Prot
      Q6AY37

    4. XM_006256977.5 → XP_006257039.2  melanoma-associated antigen B16 isoform X1

      UniProtKB/Swiss-Prot
      Q6AY37
      UniProtKB/TrEMBL
      M0R5A2
      Related
      ENSRNOP00000110263.1, ENSRNOT00000168719.1
      Conserved Domains (2) summary
      pfam01454
      Location:150 → 300
      MAGE; MAGE family
      pfam12440
      Location:3 → 99
      MAGE_N; Melanoma associated antigen family N terminal
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q6AY37.1 GenPept UniProtKB/Swiss-Prot:Q6AY37

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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