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    Zbtb39 zinc finger and BTB domain containing 39 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 299510, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Zbtb39provided by RGD
    Official Full Name
    zinc finger and BTB domain containing 39provided by RGD
    Primary source
    RGD:1306532
    See related
    EnsemblRapid:ENSRNOG00000004306 AllianceGenome:RGD:1306532
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1306532
    Summary
    Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II; regulation of cytokine production; and regulation of immune system process. Predicted to be active in nucleoplasm. Orthologous to human ZBTB39 (zinc finger and BTB domain containing 39). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Lung (RPKM 61.5), Adrenal (RPKM 53.3) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Zbtb39 in Genome Data Viewer
    Location:
    7q22
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 7 NC_086025.1 (65462255..65469806)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 7 NC_051342.1 (63576998..63584549)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 7 NC_005106.4 (71036581..71044057)

    Chromosome 7 - NC_086025.1Genomic Context describing neighboring genes Neighboring gene myosin IA Neighboring gene tachykinin precursor 3 Neighboring gene retinol dehydrogenase 16-like Neighboring gene G protein-coupled receptor 182

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    General protein information

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    Preferred Names
    zinc finger and BTB domain-containing protein 39

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001130537.2 → NP_001124009.1  zinc finger and BTB domain-containing protein 39

      See identical proteins and their annotated locations for NP_001124009.1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000007
      UniProtKB/TrEMBL
      A0A8I6ARN3, A6HQX1
      Related
      ENSRNOP00000112423.1, ENSRNOT00000125451.1
      Conserved Domains (5) summary
      sd00017
      Location:606 → 626
      ZF_C2H2; C2H2 Zn finger [structural motif]
      cd18224
      Location:4 → 126
      BTB_POZ_ZBTB39; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in zinc finger and BTB domain-containing protein 39 (ZBTB39)
      pfam00096
      Location:604 → 626
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:618 → 642
      zf-H2C2_2; Zinc-finger double domain
      cl00040
      Location:620 → 667
      C1; protein kinase C conserved region 1 (C1 domain) superfamily

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086025.1 Reference GRCr8

      Range
      65462255..65469806
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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