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    Bacc1 BPTF associated chromatin complex component 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 287452, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Bacc1provided by RGD
    Official Full Name
    BPTF associated chromatin complex component 1provided by RGD
    Primary source
    RGD:1308134
    See related
    EnsemblRapid:ENSRNOG00000018829 AllianceGenome:RGD:1308134
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1308134; C10h17orf49
    Summary
    Predicted to enable identical protein binding activity. Predicted to be located in cytosol and nucleoplasm. Predicted to be part of MLL1 complex and NURF complex. Orthologous to human C17orf49 (chromosome 17 open reading frame 49). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Lung (RPKM 54.3), Heart (RPKM 45.2) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Bacc1 in Genome Data Viewer
    Location:
    10q24
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (55450648..55453409, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (54951991..54954756, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (56843846..56848265, complement)

    Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene microRNA 497 Neighboring gene uncharacterized LOC134480816 Neighboring gene microRNA 195 Neighboring gene ribonuclease K Neighboring gene arachidonate 12-lipoxygenase, 12S type

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Physical association and coordinate function of the H3 K4 methyltransferase MLL1 and the H4 K16 acetyltransferase MOF. Dou Y, et al. Cell, 2005 Jun 17. PMID 15960975
    2. Quantitative interaction proteomics and genome-wide profiling of epigenetic histone marks and their readers. Vermeulen M, et al. Cell, 2010 Sep 17. PMID 20850016
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables identical protein binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    part_of MLL1 complex ISO
    Inferred from Sequence Orthology
    more info
    		  
    part_of NURF complex ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    chromatin complexes subunit BAP18

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001127521.3 → NP_001120993.1  chromatin complexes subunit BAP18 isoform 1

      See identical proteins and their annotated locations for NP_001120993.1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000010
      UniProtKB/TrEMBL
      A6HG37, B0BNM4
      Conserved Domains (1) summary
      pfam00249
      Location:41 → 77
      Myb_DNA-binding; Myb-like DNA-binding domain

    2. NM_001399718.1 → NP_001386647.1  chromatin complexes subunit BAP18 isoform 2

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000010
      UniProtKB/TrEMBL
      A6HG37, F7F776
      Related
      ENSRNOP00000025491.5, ENSRNOT00000025491.6

    3. NM_001399719.1 → NP_001386648.1  chromatin complexes subunit BAP18 isoform 3

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000010
      Related
      ENSRNOP00000092562.2, ENSRNOT00000113799.2

    4. NM_001399720.1 → NP_001386649.1  chromatin complexes subunit BAP18 isoform 4

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000010
      UniProtKB/TrEMBL
      A6HG36
      Conserved Domains (2) summary
      COG1395
      Location:16 → 95
      COG1395; Predicted transcriptional regulator [Transcription]
      pfam00249
      Location:41 → 77
      Myb_DNA-binding; Myb-like DNA-binding domain

    5. NM_001399721.1 → NP_001386650.1  chromatin complexes subunit BAP18 isoform 5

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000010
      UniProtKB/TrEMBL
      A0A8I6AVU2

    6. NM_001399722.1 → NP_001386651.1  chromatin complexes subunit BAP18 isoform 6

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000010

    RNA

    1. NR_174343.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000010

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086028.1 Reference GRCr8

      Range
      55450648..55453409 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063268658.1 → XP_063124728.1  chromatin complexes subunit BAP18 isoform X2

      UniProtKB/TrEMBL
      A6HG35

    2. XM_063268657.1 → XP_063124727.1  chromatin complexes subunit BAP18 isoform X1

      UniProtKB/TrEMBL
      A6HG36
    Nucleotide Protein Strain
    Heading Accession and Version

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