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    Rft1 RFT1 homolog [ Rattus norvegicus (Norway rat) ]

    Gene ID: 290552, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Rft1provided by RGD
    Official Full Name
    RFT1 homologprovided by RGD
    Primary source
    RGD:1562654
    See related
    EnsemblRapid:ENSRNOG00000021805 AllianceGenome:RGD:1562654
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1562654
    Summary
    Predicted to be involved in dolichol-linked oligosaccharide biosynthetic process and glycolipid translocation. Predicted to be active in endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation In. Orthologous to human RFT1 (RFT1 homolog). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Adrenal (RPKM 70.3), Kidney (RPKM 55.3) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Rft1 in Genome Data Viewer
    Location:
    16p16
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 16 NC_086034.1 (5833521..5867578)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 16 NC_051351.1 (5827063..5861120)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 16 NC_005115.4 (6712387..6746711)

    Chromosome 16 - NC_086034.1Genomic Context describing neighboring genes Neighboring gene protein kinase C, delta Neighboring gene uncharacterized LOC134482445 Neighboring gene uncharacterized LOC134482446 Neighboring gene small nucleolar RNA SNORA32 Neighboring gene farnesyl diphosphate synthase, pseudogene 1 Neighboring gene Scm-like with four mbt domains 1 Neighboring gene small nucleolar RNA SNORD113/SNORD114 family

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in dolichol-linked oligosaccharide biosynthetic process ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in glycolipid translocation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in glycolipid translocation ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in protein N-linked glycosylation ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    is_active_in endoplasmic reticulum membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in endoplasmic reticulum membrane ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    protein RFT1 homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001135866.1 → NP_001129338.1  protein RFT1 homolog

      Status: PROVISIONAL

      Source sequence(s)
      JAXUCZ010000016
      UniProtKB/TrEMBL
      A6KG28, D4A6W4
      Related
      ENSRNOP00000035354.4, ENSRNOT00000035542.6
      Conserved Domains (1) summary
      pfam04506
      Location:11 → 524
      Rft-1; Rft protein

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086034.1 Reference GRCr8

      Range
      5833521..5867578
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006252581.5 → XP_006252643.1  protein RFT1 homolog isoform X1

      UniProtKB/TrEMBL
      A6KG28
      Related
      ENSRNOP00000106442.1, ENSRNOT00000152898.1
      Conserved Domains (1) summary
      pfam04506
      Location:11 → 486
      Rft-1; Rft protein

    2. XM_039094264.2 → XP_038950192.1  protein RFT1 homolog isoform X2

      Conserved Domains (1) summary
      cl09326
      Location:14 → 405
      MATE_like; Multidrug and toxic compound extrusion family and similar proteins

    3. XM_063275133.1 → XP_063131203.1  protein RFT1 homolog isoform X3

    RNA

    1. XR_005494551.2 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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