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    Fuom fucose mutarotase [ Rattus norvegicus (Norway rat) ]

    Gene ID: 293587, updated on 27-Nov-2024

    Summary

    Symbol
    Fuomprovided by RGD
    Full Name
    fucose mutarotaseprovided by RGD
    Primary source
    RGD:1311186
    See related
    EnsemblRapid:ENSRNOG00000018476 AllianceGenome:RGD:1311186
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1311186
    Summary
    Predicted to enable L-fucose mutarotase activity and fucose binding activity. Predicted to be involved in fucose metabolic process and fucosylation. Predicted to act upstream of or within female mating behavior and negative regulation of neuron differentiation. Orthologous to human FUOM (fucose mutarotase). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Kidney (RPKM 81.5), Heart (RPKM 50.7) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Fuom in Genome Data Viewer
    Location:
    1q41
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (204318180..204322690, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (194888535..194893046, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (212563714..212568224, complement)

    Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene calcyon neuron-specific vesicular protein Neighboring gene proline-rich acidic protein 1 Neighboring gene enoyl-CoA hydratase, short chain 1 Neighboring gene uncharacterized LOC134485198

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables L-fucose mutarotase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables fucose binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables fucose binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables racemase and epimerase activity, acting on carbohydrates and derivatives IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables racemase and epimerase activity, acting on carbohydrates and derivatives ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in GDP-L-fucose salvage ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within female mating behavior ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in fucose metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in fucose metabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in fucosylation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within fucosylation ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within negative regulation of neuron differentiation ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of neuron differentiation ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    is_active_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    fucose mutarotase
    NP_001099780.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001106310.1NP_001099780.1  fucose mutarotase

      See identical proteins and their annotated locations for NP_001099780.1

      Status: PROVISIONAL

      Source sequence(s)
      CH473953
      UniProtKB/TrEMBL
      A6HXG1, A6HXG2, D4ACG8
      Related
      ENSRNOP00000024976.4, ENSRNOT00000024976.7
      Conserved Domains (1) summary
      pfam05025
      Location:5146
      RbsD_FucU; RbsD / FucU transport protein family

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086019.1 Reference GRCr8

      Range
      204318180..204322690 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)