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Rims1 regulating synaptic membrane exocytosis 1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 84556, updated on 27-Nov-2024

Summary

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Official Symbol: Rims1provided by RGD
Official Full Name: regulating synaptic membrane exocytosis 1provided by RGD
Primary source: RGD:620000
See related: EnsemblRapid:ENSRNOG00000011000 AllianceGenome:RGD:620000
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: Rim1; RIM1a
Summary: Enables SH3 domain binding activity; protein kinase binding activity; and small GTPase binding activity. Involved in long-term synaptic potentiation; positive regulation of inhibitory postsynaptic potential; and positive regulation of synaptic vesicle priming. Located in presynaptic membrane. Is active in glutamatergic synapse and presynaptic active zone cytoplasmic component. Orthologous to human RIMS1 (regulating synaptic membrane exocytosis 1). [provided by Alliance of Genome Resources, Nov 2024]
Expression: Biased expression in Brain (RPKM 145.5), Uterus (RPKM 16.1) and 1 other tissue See more
Orthologs: human mouse all
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Genomic context

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See Rims1 in Genome Data Viewer

Location:: 9q13

Exon count:: 39

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	9	NC_086027.1 (32193352..32692998, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	9	NC_051344.1 (24696959..25196404, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	9	NC_005108.4 (28440408..28973246, complement)

Chromosome 9 - NC_086027.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

RIM1a and RIM-BP2 are plausible organizers of active zones, and the formation of RIM and RIM-BP condensates may cluster voltage gated calcium channels into nano- or microdomains and position the clustered Ca(2+) channels with Ca(2+) sensors on docked vesicles for efficient and precise synaptic transmissions.
Title: RIM and RIM-BP Form Presynaptic Active-Zone-like Condensates via Phase Separation.
RIM1alpha SUMOylation at K502 is required for its binding to Cav2.1 and for fast synaptic vesicle exocytosis.
Title: RIM1α SUMOylation is required for fast synaptic vesicle exocytosis.
Depletion of liprin-alpha2 resulted in reduced turnover of RIM1 and CASK at presynaptic terminals, suggesting that liprin-alpha2 promotes dynamic scaffolding for molecular complexes that facilitate synaptic vesicle release.
Title: Liprin-α2 promotes the presynaptic recruitment and turnover of RIM1/CASK to facilitate synaptic transmission.
Data show that Bassoon colocalizes with Aczonin at conventional synapses, but in ribbon synapses, CAST, Munc13, and RIM are segregated from Aczonin, and Aczonin is positioned and may control the access of neurotransmitter vesicles to the fusion site.
Title: Molecular in situ topology of Aczonin/Piccolo and associated proteins at the mammalian neurotransmitter release site.
Presynaptic silencing was accompanied by decreases in levels of the priming proteins Munc13-1 and Rim1.
Title: A role for the ubiquitin-proteasome system in activity-dependent presynaptic silencing.
The crystal structure of the RIM1alpha C2B domain dimer reveals that it forms a beta-sandwich and that the unique N- and C-terminal extensions form a small subdomain that packs against the beta-sandwich and mediates dimerization.
Title: Crystal structure of the RIM1alpha C2B domain at 1.7 A resolution.
These data demonstrate that alpha-RIMs are not essential for synapse formation or synaptic exocytosis, but are required for normal Ca(2+)-triggering of exocytosis.
Title: Redundant functions of RIM1alpha and RIM2alpha in Ca(2+)-triggered neurotransmitter release.
RIM1- or Bassoon-binding region of CAST impairs synaptic transmission in cultured superior cervical ganglion neurons.
Title: Physical and functional interaction of the active zone proteins, CAST, RIM1, and Bassoon, in neurotransmitter release.
Rab3A-interacting molecule RIM regulates the presynaptic recruitment of Munc13-1 and ubMunc13-2
Title: Binding to Rab3A-interacting molecule RIM regulates the presynaptic recruitment of Munc13-1 and ubMunc13-2.

Submit: New GeneRIF Correction

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

BF401631 (e-PCR)
- UniSTS:245513

RH138351 (e-PCR)
- UniSTS:220438

AI406393 (e-PCR)
- UniSTS:261686

AU048318 (e-PCR)
- UniSTS:109654

BF390485 (e-PCR)
- UniSTS:249482

BE113512 (e-PCR)
- UniSTS:246690

BF400263 (e-PCR)
- UniSTS:244905

BF386262 (e-PCR)
- UniSTS:243647

BE101604 (e-PCR)
- UniSTS:243655

BF405023 (e-PCR)
- UniSTS:247768

D9Wox34 (e-PCR)
- UniSTS:240383

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables SH3 domain binding	IPI Inferred from Physical Interaction more info	PubMed
enables metal ion binding	IEA Inferred from Electronic Annotation more info
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed
enables protein kinase binding	IPI Inferred from Physical Interaction more info	PubMed
enables small GTPase binding	IEA Inferred from Electronic Annotation more info
enables small GTPase binding	IPI Inferred from Physical Interaction more info	PubMed
enables structural constituent of presynaptic active zone	IBA Inferred from Biological aspect of Ancestor more info
enables structural constituent of presynaptic active zone	ISO Inferred from Sequence Orthology more info
enables transmembrane transporter binding	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in acrosomal vesicle exocytosis	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within calcium ion-regulated exocytosis of neurotransmitter	ISO Inferred from Sequence Orthology more info
involved_in cell differentiation	IEA Inferred from Electronic Annotation more info
involved_in exocytosis	IEA Inferred from Electronic Annotation more info
involved_in intracellular protein transport	IEA Inferred from Electronic Annotation more info
involved_in long-term synaptic potentiation	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in maintenance of presynaptic active zone structure	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within neurotransmitter secretion	ISO Inferred from Sequence Orthology more info
involved_in neurotransmitter transport	IEA Inferred from Electronic Annotation more info
involved_in positive regulation of dendrite extension	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of excitatory postsynaptic potential	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of excitatory postsynaptic potential	ISS Inferred from Sequence or Structural Similarity more info
involved_in positive regulation of gene expression	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of gene expression	ISS Inferred from Sequence or Structural Similarity more info
involved_in positive regulation of inhibitory postsynaptic potential	IGI Inferred from Genetic Interaction more info	PubMed
involved_in positive regulation of inhibitory postsynaptic potential	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of inhibitory postsynaptic potential	ISS Inferred from Sequence or Structural Similarity more info
involved_in positive regulation of synaptic vesicle fusion to presynaptic active zone membrane	NAS Non-traceable Author Statement more info	PubMed
involved_in positive regulation of synaptic vesicle priming	IGI Inferred from Genetic Interaction more info	PubMed
involved_in presynaptic dense core vesicle exocytosis	ISO Inferred from Sequence Orthology more info
involved_in protein-containing complex assembly	ISO Inferred from Sequence Orthology more info
involved_in regulation of calcium-dependent activation of synaptic vesicle fusion	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within regulation of long-term neuronal synaptic plasticity	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within regulation of membrane potential	ISO Inferred from Sequence Orthology more info
involved_in regulation of synaptic vesicle exocytosis	IBA Inferred from Biological aspect of Ancestor more info
involved_in spontaneous neurotransmitter secretion	ISO Inferred from Sequence Orthology more info
involved_in synaptic vesicle docking	IBA Inferred from Biological aspect of Ancestor more info
involved_in synaptic vesicle docking	ISO Inferred from Sequence Orthology more info
involved_in synaptic vesicle priming	IBA Inferred from Biological aspect of Ancestor more info
involved_in synaptic vesicle priming	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
is_active_in GABA-ergic synapse	ISO Inferred from Sequence Orthology more info
located_in cell projection	IEA Inferred from Electronic Annotation more info
is_active_in extrinsic component of presynaptic active zone membrane	ISO Inferred from Sequence Orthology more info
is_active_in glutamatergic synapse	IDA Inferred from Direct Assay more info	PubMed
is_active_in glutamatergic synapse	ISO Inferred from Sequence Orthology more info
located_in inhibitory synapse	ISO Inferred from Sequence Orthology more info
located_in membrane	IEA Inferred from Electronic Annotation more info
located_in plasma membrane	IGI Inferred from Genetic Interaction more info	PubMed
located_in postsynaptic density	ISO Inferred from Sequence Orthology more info
is_active_in presynaptic active zone cytoplasmic component	IBA Inferred from Biological aspect of Ancestor more info
is_active_in presynaptic active zone cytoplasmic component	IDA Inferred from Direct Assay more info	PubMed
is_active_in presynaptic active zone cytoplasmic component	ISO Inferred from Sequence Orthology more info
is_active_in presynaptic membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in presynaptic membrane	IDA Inferred from Direct Assay more info	PubMed
located_in synapse	IEA Inferred from Electronic Annotation more info
located_in synapse	ISO Inferred from Sequence Orthology more info
located_in vesicle	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: regulating synaptic membrane exocytosis protein 1

Names: RIM 1; Rab3 effector; Rim1b protein; rab-3-interacting molecule 1; rab3-interacting molecule 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001398595.2 → NP_001385524.1 regulating synaptic membrane exocytosis protein 1 isoform 1

Status: VALIDATED

Source sequence(s)

JAXUCZ010000009

UniProtKB/TrEMBL

A0A0G2JT77

Related

ENSRNOP00000085276.2, ENSRNOT00000109109.2

Conserved Domains (7) summary

cd04028
Location:1445 → 1590

C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins

cd04031
Location:756 → 882

C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins

PLN03237
Location:433 → 550

PLN03237; DNA topoisomerase 2; Provisional

PHA03307
Location:887 → 1207

PHA03307; transcriptional regulator ICP4; Provisional

cd00992
Location:618 → 703

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

pfam04642
Location:214 → 316

DUF601; Protein of unknown function, DUF601

cl28890
Location:154 → 209

FYVE_like_SF; FYVE domain like superfamily
NM_052829.4 → NP_439894.2 regulating synaptic membrane exocytosis protein 1 isoform 2

Status: VALIDATED

Source sequence(s)

JAXUCZ010000009

UniProtKB/Swiss-Prot

O35168, Q9JIR4

Related

ENSRNOP00000015454.8, ENSRNOT00000015453.8

Conserved Domains (6) summary

cd04028
Location:1384 → 1529

C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins

cd04031
Location:756 → 882

C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins

PLN03237
Location:433 → 550

PLN03237; DNA topoisomerase 2; Provisional

cd00992
Location:618 → 703

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

pfam04642
Location:214 → 316

DUF601; Protein of unknown function, DUF601

cl28890
Location:154 → 209

FYVE_like_SF; FYVE domain like superfamily

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

NC_086027.1 Reference GRCr8

Range

32193352..32692998 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_063267779.1 → XP_063123849.1 regulating synaptic membrane exocytosis protein 1 isoform X9
XM_017596679.3 → XP_017452168.2 regulating synaptic membrane exocytosis protein 1 isoform X42

UniProtKB/TrEMBL

F1LYS1

Conserved Domains (8) summary

cd04028
Location:1247 → 1392

C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins

cd04031
Location:702 → 828

C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins

PLN03237
Location:379 → 496

PLN03237; DNA topoisomerase 2; Provisional

PHA03307
Location:877 → 1176

PHA03307; transcriptional regulator ICP4; Provisional

cd00992
Location:564 → 649

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

pfam04642
Location:160 → 262

DUF601; Protein of unknown function, DUF601

cl28890
Location:104 → 155

FYVE_like_SF; FYVE domain like superfamily

cl22851
Location:26 → 149

PHD_SF; PHD finger superfamily
XM_039084268.2 → XP_038940196.1 regulating synaptic membrane exocytosis protein 1 isoform X10

UniProtKB/TrEMBL

F1LYS1

Conserved Domains (8) summary

cd04028
Location:1419 → 1564

C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins

cd04031
Location:702 → 828

C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins

PLN03237
Location:379 → 496

PLN03237; DNA topoisomerase 2; Provisional

PHA03307
Location:833 → 1187

PHA03307; transcriptional regulator ICP4; Provisional

cd00992
Location:564 → 649

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

pfam04642
Location:160 → 262

DUF601; Protein of unknown function, DUF601

cl28890
Location:104 → 155

FYVE_like_SF; FYVE domain like superfamily

cl22851
Location:26 → 149

PHD_SF; PHD finger superfamily
XM_039084294.2 → XP_038940222.1 regulating synaptic membrane exocytosis protein 1 isoform X41

UniProtKB/TrEMBL

F1LYS1

Conserved Domains (8) summary

cd04028
Location:1251 → 1396

C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins

cd04031
Location:706 → 832

C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins

PLN03237
Location:383 → 500

PLN03237; DNA topoisomerase 2; Provisional

PHA03307
Location:881 → 1180

PHA03307; transcriptional regulator ICP4; Provisional

cd00992
Location:568 → 653

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

pfam04642
Location:164 → 266

DUF601; Protein of unknown function, DUF601

cl28890
Location:104 → 159

FYVE_like_SF; FYVE domain like superfamily

cl22851
Location:26 → 153

PHD_SF; PHD finger superfamily
XM_017596678.3 → XP_017452167.2 regulating synaptic membrane exocytosis protein 1 isoform X8

UniProtKB/TrEMBL

F1LYS1

Conserved Domains (8) summary

cd04028
Location:1423 → 1568

C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins

cd04031
Location:706 → 832

C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins

PLN03237
Location:383 → 500

PLN03237; DNA topoisomerase 2; Provisional

PHA03307
Location:837 → 1191

PHA03307; transcriptional regulator ICP4; Provisional

cd00992
Location:568 → 653

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

pfam04642
Location:164 → 266

DUF601; Protein of unknown function, DUF601

cl28890
Location:104 → 159

FYVE_like_SF; FYVE domain like superfamily

cl22851
Location:26 → 153

PHD_SF; PHD finger superfamily
XM_039084265.2 → XP_038940193.1 regulating synaptic membrane exocytosis protein 1 isoform X7

UniProtKB/Swiss-Prot

O35168, Q9JIR4

Conserved Domains (7) summary

cd04028
Location:1446 → 1591

C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins

cd04031
Location:729 → 855

C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins

PLN03237
Location:406 → 523

PLN03237; DNA topoisomerase 2; Provisional

PHA03307
Location:860 → 1214

PHA03307; transcriptional regulator ICP4; Provisional

cd00992
Location:591 → 676

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

pfam04642
Location:187 → 289

DUF601; Protein of unknown function, DUF601

cl28890
Location:127 → 182

FYVE_like_SF; FYVE domain like superfamily
XM_039084263.2 → XP_038940191.1 regulating synaptic membrane exocytosis protein 1 isoform X5

UniProtKB/Swiss-Prot

O35168, Q9JIR4

Conserved Domains (7) summary

cd04028
Location:1449 → 1594

C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins

cd04031
Location:732 → 858

C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins

PLN03237
Location:409 → 526

PLN03237; DNA topoisomerase 2; Provisional

PHA03307
Location:863 → 1217

PHA03307; transcriptional regulator ICP4; Provisional

cd00992
Location:594 → 679

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

pfam04642
Location:190 → 292

DUF601; Protein of unknown function, DUF601

cl28890
Location:130 → 185

FYVE_like_SF; FYVE domain like superfamily
XM_063267781.1 → XP_063123851.1 regulating synaptic membrane exocytosis protein 1 isoform X19
XM_039084261.2 → XP_038940189.1 regulating synaptic membrane exocytosis protein 1 isoform X4

UniProtKB/Swiss-Prot

O35168, Q9JIR4

Conserved Domains (7) summary

cd04028
Location:1450 → 1595

C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins

cd04031
Location:733 → 859

C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins

PLN03237
Location:410 → 527

PLN03237; DNA topoisomerase 2; Provisional

PHA03307
Location:864 → 1218

PHA03307; transcriptional regulator ICP4; Provisional

cd00992
Location:595 → 680

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

pfam04642
Location:191 → 293

DUF601; Protein of unknown function, DUF601

cl28890
Location:131 → 186

FYVE_like_SF; FYVE domain like superfamily
XM_039084259.2 → XP_038940187.1 regulating synaptic membrane exocytosis protein 1 isoform X2

UniProtKB/Swiss-Prot

O35168, Q9JIR4

Conserved Domains (7) summary

cd04028
Location:1469 → 1614

C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins

cd04031
Location:752 → 878

C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins

PLN03237
Location:429 → 546

PLN03237; DNA topoisomerase 2; Provisional

PHA03307
Location:883 → 1237

PHA03307; transcriptional regulator ICP4; Provisional

cd00992
Location:614 → 699

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

pfam04642
Location:210 → 312

DUF601; Protein of unknown function, DUF601

cl28890
Location:154 → 205

FYVE_like_SF; FYVE domain like superfamily
XM_039084264.2 → XP_038940192.1 regulating synaptic membrane exocytosis protein 1 isoform X6

UniProtKB/Swiss-Prot

O35168, Q9JIR4

Conserved Domains (7) summary

cd04028
Location:1449 → 1594

C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins

cd04031
Location:756 → 882

C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins

PLN03237
Location:433 → 550

PLN03237; DNA topoisomerase 2; Provisional

PHA03307
Location:955 → 1217

PHA03307; transcriptional regulator ICP4; Provisional

cd00992
Location:618 → 703

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

pfam04642
Location:214 → 316

DUF601; Protein of unknown function, DUF601

cl28890
Location:154 → 209

FYVE_like_SF; FYVE domain like superfamily
XM_039084287.2 → XP_038940215.1 regulating synaptic membrane exocytosis protein 1 isoform X34

UniProtKB/TrEMBL

A0A8I6GLS3

Conserved Domains (6) summary

cd04028
Location:1137 → 1282

C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins

cd04031
Location:756 → 882

C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins

PLN03237
Location:433 → 550

PLN03237; DNA topoisomerase 2; Provisional

cd00992
Location:618 → 703

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

pfam04642
Location:214 → 316

DUF601; Protein of unknown function, DUF601

cl28890
Location:154 → 209

FYVE_like_SF; FYVE domain like superfamily
XM_039084279.2 → XP_038940207.1 regulating synaptic membrane exocytosis protein 1 isoform X25

UniProtKB/TrEMBL

A0A8I6GLS3

Conserved Domains (6) summary

cd04028
Location:1300 → 1445

C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins

cd04031
Location:756 → 882

C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins

PLN03237
Location:433 → 550

PLN03237; DNA topoisomerase 2; Provisional

cd00992
Location:618 → 703

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

pfam04642
Location:214 → 316

DUF601; Protein of unknown function, DUF601

cl28890
Location:154 → 209

FYVE_like_SF; FYVE domain like superfamily
XM_017596670.3 → XP_017452159.2 regulating synaptic membrane exocytosis protein 1 isoform X23

UniProtKB/TrEMBL

A0A8I6GLS3

Related

ENSRNOP00000095741.2, ENSRNOT00000110625.2

Conserved Domains (6) summary

cd04028
Location:1309 → 1454

C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins

cd04031
Location:756 → 882

C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins

PLN03237
Location:433 → 550

PLN03237; DNA topoisomerase 2; Provisional

cd00992
Location:618 → 703

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

pfam04642
Location:214 → 316

DUF601; Protein of unknown function, DUF601

cl28890
Location:154 → 209

FYVE_like_SF; FYVE domain like superfamily
XM_039084275.2 → XP_038940203.1 regulating synaptic membrane exocytosis protein 1 isoform X16

UniProtKB/Swiss-Prot

O35168, Q9JIR4

Conserved Domains (6) summary

cd04028
Location:1370 → 1515

C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins

cd04031
Location:756 → 882

C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins

PLN03237
Location:433 → 550

PLN03237; DNA topoisomerase 2; Provisional

cd00992
Location:618 → 703

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

pfam04642
Location:214 → 316

DUF601; Protein of unknown function, DUF601

cl28890
Location:154 → 209

FYVE_like_SF; FYVE domain like superfamily
XM_039084285.2 → XP_038940213.1 regulating synaptic membrane exocytosis protein 1 isoform X32

UniProtKB/TrEMBL

A0A8I6GLS3

Conserved Domains (6) summary

cd04028
Location:1161 → 1306

C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins

cd04031
Location:756 → 882

C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins

PLN03237
Location:433 → 550

PLN03237; DNA topoisomerase 2; Provisional

cd00992
Location:618 → 703

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

pfam04642
Location:214 → 316

DUF601; Protein of unknown function, DUF601

cl28890
Location:154 → 209

FYVE_like_SF; FYVE domain like superfamily
XM_039084277.2 → XP_038940205.1 regulating synaptic membrane exocytosis protein 1 isoform X20

UniProtKB/TrEMBL

A0A8I6GLS3

Conserved Domains (6) summary

cd04028
Location:1333 → 1478

C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins

cd04031
Location:756 → 882

C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins

PLN03237
Location:433 → 550

PLN03237; DNA topoisomerase 2; Provisional

cd00992
Location:618 → 703

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

pfam04642
Location:214 → 316

DUF601; Protein of unknown function, DUF601

cl28890
Location:154 → 209

FYVE_like_SF; FYVE domain like superfamily
XM_039084271.2 → XP_038940199.1 regulating synaptic membrane exocytosis protein 1 isoform X13

UniProtKB/Swiss-Prot

O35168, Q9JIR4

Conserved Domains (7) summary

cd04028
Location:1394 → 1539

C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins

cd04031
Location:756 → 882

C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins

PHA03381
Location:999 → 1130

PHA03381; tegument protein VP22; Provisional

PLN03237
Location:433 → 550

PLN03237; DNA topoisomerase 2; Provisional

cd00992
Location:618 → 703

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

pfam04642
Location:214 → 316

DUF601; Protein of unknown function, DUF601

cl28890
Location:154 → 209

FYVE_like_SF; FYVE domain like superfamily
XM_039084286.2 → XP_038940214.1 regulating synaptic membrane exocytosis protein 1 isoform X33

UniProtKB/TrEMBL

A0A8I6GLS3

Conserved Domains (6) summary

cd04028
Location:1158 → 1303

C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins

cd04031
Location:756 → 882

C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins

PLN03237
Location:433 → 550

PLN03237; DNA topoisomerase 2; Provisional

cd00992
Location:618 → 703

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

pfam04642
Location:214 → 316

DUF601; Protein of unknown function, DUF601

cl28890
Location:154 → 209

FYVE_like_SF; FYVE domain like superfamily
XM_063267782.1 → XP_063123852.1 regulating synaptic membrane exocytosis protein 1 isoform X22
XM_039084278.2 → XP_038940206.1 regulating synaptic membrane exocytosis protein 1 isoform X21

UniProtKB/TrEMBL

A0A8I6GLS3

Conserved Domains (6) summary

cd04028
Location:1330 → 1475

C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins

cd04031
Location:756 → 882

C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins

PLN03237
Location:433 → 550

PLN03237; DNA topoisomerase 2; Provisional

cd00992
Location:618 → 703

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

pfam04642
Location:214 → 316

DUF601; Protein of unknown function, DUF601

cl28890
Location:154 → 209

FYVE_like_SF; FYVE domain like superfamily
XM_017596673.3 → XP_017452162.2 regulating synaptic membrane exocytosis protein 1 isoform X31

UniProtKB/Swiss-Prot

O35168, Q9JIR4

Conserved Domains (6) summary

cd04028
Location:1188 → 1333

C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins

cd04031
Location:756 → 882

C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins

PLN03237
Location:433 → 550

PLN03237; DNA topoisomerase 2; Provisional

cd00992
Location:618 → 703

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

pfam04642
Location:214 → 316

DUF601; Protein of unknown function, DUF601

cl28890
Location:154 → 209

FYVE_like_SF; FYVE domain like superfamily
XM_039084276.2 → XP_038940204.1 regulating synaptic membrane exocytosis protein 1 isoform X18

UniProtKB/Swiss-Prot

O35168, Q9JIR4

Conserved Domains (6) summary

cd04028
Location:1351 → 1496

C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins

cd04031
Location:756 → 882

C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins

PLN03237
Location:433 → 550

PLN03237; DNA topoisomerase 2; Provisional

cd00992
Location:618 → 703

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

pfam04642
Location:214 → 316

DUF601; Protein of unknown function, DUF601

cl28890
Location:154 → 209

FYVE_like_SF; FYVE domain like superfamily
XM_017596667.3 → XP_017452156.2 regulating synaptic membrane exocytosis protein 1 isoform X17

UniProtKB/Swiss-Prot

O35168, Q9JIR4

Related

ENSRNOP00000074013.3, ENSRNOT00000086967.3

Conserved Domains (6) summary

cd04028
Location:1360 → 1505

C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins

cd04031
Location:756 → 882

C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins

PLN03237
Location:433 → 550

PLN03237; DNA topoisomerase 2; Provisional

cd00992
Location:618 → 703

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

pfam04642
Location:214 → 316

DUF601; Protein of unknown function, DUF601

cl28890
Location:154 → 209

FYVE_like_SF; FYVE domain like superfamily
XM_017596672.3 → XP_017452161.2 regulating synaptic membrane exocytosis protein 1 isoform X30

UniProtKB/Swiss-Prot

O35168, Q9JIR4

Conserved Domains (6) summary

cd04028
Location:1212 → 1357

C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins

cd04031
Location:756 → 882

C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins

PLN03237
Location:433 → 550

PLN03237; DNA topoisomerase 2; Provisional

cd00992
Location:618 → 703

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

pfam04642
Location:214 → 316

DUF601; Protein of unknown function, DUF601

cl28890
Location:154 → 209

FYVE_like_SF; FYVE domain like superfamily
XM_039084274.2 → XP_038940202.1 regulating synaptic membrane exocytosis protein 1 isoform X15

UniProtKB/Swiss-Prot

O35168, Q9JIR4

Conserved Domains (6) summary

cd04028
Location:1375 → 1520

C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins

cd04031
Location:756 → 882

C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins

PLN03237
Location:433 → 550

PLN03237; DNA topoisomerase 2; Provisional

cd00992
Location:618 → 703

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

pfam04642
Location:214 → 316

DUF601; Protein of unknown function, DUF601

cl28890
Location:154 → 209

FYVE_like_SF; FYVE domain like superfamily
XM_039084282.2 → XP_038940210.1 regulating synaptic membrane exocytosis protein 1 isoform X27

UniProtKB/Swiss-Prot

O35168, Q9JIR4

Conserved Domains (7) summary

cd04028
Location:1273 → 1418

C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins

cd04031
Location:756 → 882

C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins

PLN03237
Location:433 → 550

PLN03237; DNA topoisomerase 2; Provisional

PHA03307
Location:887 → 1202

PHA03307; transcriptional regulator ICP4; Provisional

cd00992
Location:618 → 703

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

pfam04642
Location:214 → 316

DUF601; Protein of unknown function, DUF601

cl28890
Location:154 → 209

FYVE_like_SF; FYVE domain like superfamily
XM_063267785.1 → XP_063123855.1 regulating synaptic membrane exocytosis protein 1 isoform X29
XM_039084273.2 → XP_038940201.1 regulating synaptic membrane exocytosis protein 1 isoform X14

UniProtKB/TrEMBL

F1LYS1

Conserved Domains (7) summary

cd04028
Location:1388 → 1533

C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins

cd04031
Location:756 → 882

C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins

PLN03237
Location:433 → 550

PLN03237; DNA topoisomerase 2; Provisional

PHA02666
Location:940 → 1129

PHA02666; hypothetical protein; Provisional

cd00992
Location:618 → 703

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

pfam04642
Location:214 → 316

DUF601; Protein of unknown function, DUF601

cl28890
Location:154 → 209

FYVE_like_SF; FYVE domain like superfamily
XM_039084283.2 → XP_038940211.1 regulating synaptic membrane exocytosis protein 1 isoform X28

UniProtKB/TrEMBL

F1LYS1

Conserved Domains (7) summary

cd04028
Location:1240 → 1385

C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins

cd04031
Location:756 → 882

C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins

PLN03237
Location:433 → 550

PLN03237; DNA topoisomerase 2; Provisional

PHA03307
Location:885 → 1154

PHA03307; transcriptional regulator ICP4; Provisional

cd00992
Location:618 → 703

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

pfam04642
Location:214 → 316

DUF601; Protein of unknown function, DUF601

cl28890
Location:154 → 209

FYVE_like_SF; FYVE domain like superfamily
XM_039084270.2 → XP_038940198.1 regulating synaptic membrane exocytosis protein 1 isoform X12

UniProtKB/TrEMBL

F1LYS1

Conserved Domains (7) summary

cd04028
Location:1403 → 1548

C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins

cd04031
Location:756 → 882

C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins

PLN03237
Location:433 → 550

PLN03237; DNA topoisomerase 2; Provisional

PHA03307
Location:885 → 1154

PHA03307; transcriptional regulator ICP4; Provisional

cd00992
Location:618 → 703

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

pfam04642
Location:214 → 316

DUF601; Protein of unknown function, DUF601

cl28890
Location:154 → 209

FYVE_like_SF; FYVE domain like superfamily
XM_039084269.2 → XP_038940197.1 regulating synaptic membrane exocytosis protein 1 isoform X11

UniProtKB/TrEMBL

F1LYS1

Conserved Domains (7) summary

cd04028
Location:1412 → 1557

C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins

cd04031
Location:756 → 882

C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins

PLN03237
Location:433 → 550

PLN03237; DNA topoisomerase 2; Provisional

PHA03307
Location:885 → 1154

PHA03307; transcriptional regulator ICP4; Provisional

cd00992
Location:618 → 703

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

pfam04642
Location:214 → 316

DUF601; Protein of unknown function, DUF601

cl28890
Location:154 → 209

FYVE_like_SF; FYVE domain like superfamily
XM_017596671.3 → XP_017452160.2 regulating synaptic membrane exocytosis protein 1 isoform X24

UniProtKB/Swiss-Prot

O35168, Q9JIR4

Conserved Domains (7) summary

cd04028
Location:1301 → 1446

C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins

cd04031
Location:756 → 882

C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins

PLN03237
Location:433 → 550

PLN03237; DNA topoisomerase 2; Provisional

PHA03307
Location:931 → 1230

PHA03307; transcriptional regulator ICP4; Provisional

cd00992
Location:618 → 703

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

pfam04642
Location:214 → 316

DUF601; Protein of unknown function, DUF601

cl28890
Location:154 → 209

FYVE_like_SF; FYVE domain like superfamily
XM_039084260.2 → XP_038940188.1 regulating synaptic membrane exocytosis protein 1 isoform X3

UniProtKB/Swiss-Prot

O35168, Q9JIR4

Conserved Domains (7) summary

cd04028
Location:1464 → 1609

C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins

cd04031
Location:756 → 882

C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins

PLN03237
Location:433 → 550

PLN03237; DNA topoisomerase 2; Provisional

PHA03307
Location:887 → 1241

PHA03307; transcriptional regulator ICP4; Provisional

cd00992
Location:618 → 703

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

pfam04642
Location:214 → 316

DUF601; Protein of unknown function, DUF601

cl28890
Location:154 → 209

FYVE_like_SF; FYVE domain like superfamily
XM_017596657.3 → XP_017452146.2 regulating synaptic membrane exocytosis protein 1 isoform X1

UniProtKB/Swiss-Prot

O35168, Q9JIR4

Related

ENSRNOP00000086155.2, ENSRNOT00000099201.2

Conserved Domains (7) summary

cd04028
Location:1473 → 1618

C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins

cd04031
Location:756 → 882

C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins

PLN03237
Location:433 → 550

PLN03237; DNA topoisomerase 2; Provisional

PHA03307
Location:887 → 1241

PHA03307; transcriptional regulator ICP4; Provisional

cd00992
Location:618 → 703

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

pfam04642
Location:214 → 316

DUF601; Protein of unknown function, DUF601

cl28890
Location:154 → 209

FYVE_like_SF; FYVE domain like superfamily
XM_063267783.1 → XP_063123853.1 regulating synaptic membrane exocytosis protein 1 isoform X26
XM_039084290.2 → XP_038940218.1 regulating synaptic membrane exocytosis protein 1 isoform X36

UniProtKB/TrEMBL

A6JJA0

Conserved Domains (4) summary

cd04028
Location:938 → 1083

C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins

cd04031
Location:221 → 347

C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins

PHA03307
Location:352 → 706

PHA03307; transcriptional regulator ICP4; Provisional

cd00992
Location:83 → 168

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
XM_039084292.2 → XP_038940220.1 regulating synaptic membrane exocytosis protein 1 isoform X38

UniProtKB/TrEMBL

A6JJA0

Conserved Domains (4) summary

cd04028
Location:852 → 997

C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins

cd04031
Location:135 → 261

C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins

PHA03307
Location:266 → 620

PHA03307; transcriptional regulator ICP4; Provisional

cd00992
Location:1 → 82

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
XM_039084291.2 → XP_038940219.1 regulating synaptic membrane exocytosis protein 1 isoform X37

UniProtKB/TrEMBL

A6JJA0

Conserved Domains (4) summary

cd04028
Location:903 → 1048

C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins

cd04031
Location:186 → 312

C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins

PHA03307
Location:317 → 671

PHA03307; transcriptional regulator ICP4; Provisional

cd00992
Location:48 → 133

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
XM_039084293.2 → XP_038940221.1 regulating synaptic membrane exocytosis protein 1 isoform X39

Conserved Domains (1) summary

cd04028
Location:229 → 374

C2B_RIM1alpha; C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins
XM_063267786.1 → XP_063123856.1 regulating synaptic membrane exocytosis protein 1 isoform X40
XM_039084288.2 → XP_038940216.1 regulating synaptic membrane exocytosis protein 1 isoform X35

Conserved Domains (6) summary

cd04031
Location:756 → 882

C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins

PLN03237
Location:433 → 550

PLN03237; DNA topoisomerase 2; Provisional

PHA03307
Location:887 → 1241

PHA03307; transcriptional regulator ICP4; Provisional

cd00992
Location:618 → 703

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

pfam04642
Location:214 → 316

DUF601; Protein of unknown function, DUF601

cl28890
Location:154 → 209

FYVE_like_SF; FYVE domain like superfamily