Klra5 killer cell lectin-like receptor, subfamily A, member 5 [Rattus norvegicus (Norway rat)] - Gene

Summary

Symbol: Klra5provided by RGD
Full Name: killer cell lectin-like receptor, subfamily A, member 5provided by RGD
Primary source: RGD:735134
See related: EnsemblRapid:ENSRNOG00000061664 AllianceGenome:RGD:735134
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: Ly-49.9
Summary: Predicted to enable signaling receptor activity. Predicted to be involved in regulation of signal transduction. Predicted to be located in plasma membrane. Predicted to be active in cell surface. [provided by Alliance of Genome Resources, Nov 2024]
Expression: Biased expression in Spleen (RPKM 28.0), Lung (RPKM 17.4) and 7 other tissues See more
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Genomic context

Location:: 4q42

Exon count:: 9

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	4	NC_086022.1 (166491210..166556087, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	4	NC_051339.1 (164761839..164824367, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	4	NC_005103.4 (165169417..165317573, complement)

Chromosome 4 - NC_086022.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables carbohydrate binding	IEA Inferred from Electronic Annotation more info
enables signaling receptor activity	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in cell adhesion	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in cell surface	IBA Inferred from Biological aspect of Ancestor more info
located_in plasma membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: killer cell lectin-like receptor, subfamily A, member 5

Names: Ly-49.9 antigen; killer cell lectin-like receptor 5; killer cell lectin-like receptor 5-like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_198746.4 → NP_942041.3 killer cell lectin-like receptor, subfamily A, member 5

Status: VALIDATED

Source sequence(s)

JAXUCZ010000004

UniProtKB/TrEMBL

A6IM90, E9PTN0, Q62982

Related

ENSRNOP00000065392.3, ENSRNOT00000073877.3

Conserved Domains (2) summary

cd03593
Location:145 → 260

CLECT_NK_receptors_like; C-type lectin-like domain (CTLD) of the type found in natural killer cell receptors (NKRs)

pfam08391
Location:40 → 157

Ly49; Ly49-like protein, N-terminal region

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

NC_086022.1 Reference GRCr8

Range

166491210..166556087 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_063285916.1 → XP_063141986.1 killer cell lectin-like receptor, subfamily A, member 5 isoform X2
XM_039107455.2 → XP_038963383.1 killer cell lectin-like receptor, subfamily A, member 5 isoform X1

Related

ENSRNOP00000069231.4, ENSRNOT00000087529.4

Conserved Domains (2) summary

cd03593
Location:211 → 326

CLECT_NK_receptors_like; C-type lectin-like domain (CTLD) of the type found in natural killer cell receptors (NKRs)

pfam08391
Location:106 → 223

Ly49; Ly49-like protein, N-terminal region