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    Slc25a32 solute carrier family 25, member 32 [ Mus musculus (house mouse) ]

    Gene ID: 69906, updated on 27-Dec-2024

    Summary

    Official Symbol
    Slc25a32provided by MGI
    Official Full Name
    solute carrier family 25, member 32provided by MGI
    Primary source
    MGI:MGI:1917156
    See related
    Ensembl:ENSMUSG00000022299 AllianceGenome:MGI:1917156
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Mftc; 2610043O12Rik
    Summary
    Enables FAD transmembrane transporter activity. Involved in mitochondrial FAD transmembrane transport. Located in mitochondrion. Is expressed in embryo; metencephalon floor plate; and skeletal muscle. Orthologous to human SLC25A32 (solute carrier family 25 member 32). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in bladder adult (RPKM 2.4), adrenal adult (RPKM 2.1) and 28 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Slc25a32 in Genome Data Viewer
    Location:
    15 B3.1; 15 15.39 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 15 NC_000081.7 (38954625..38976213, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (39091230..39112720, complement)

    Chromosome 15 - NC_000081.7Genomic Context describing neighboring genes Neighboring gene predicted gene 7194 Neighboring gene STARR-seq mESC enhancer starr_38471 Neighboring gene collagen triple helix repeat containing 1 Neighboring gene STARR-seq mESC enhancer starr_38472 Neighboring gene STARR-positive B cell enhancer mm9_chr15:38944202-38944502 Neighboring gene DDB1 and CUL4 associated factor 13 Neighboring gene STARR-seq mESC enhancer starr_38473 Neighboring gene STARR-seq mESC enhancer starr_38474 Neighboring gene glyceraldehyde-3-phosphate dehydrogenase pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (5)  1 citation
    • Gene trapped (1) 

    Pathways from PubChem

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables FAD transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables FAD transmembrane transporter activity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    enables FAD transmembrane transporter activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables folic acid transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables folic acid transmembrane transporter activity ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in folate import into mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in folate import into mitochondrion ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in folate import into mitochondrion ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in mitochondrial FAD transmembrane transport IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in mitochondrial FAD transmembrane transport ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in mitochondrial FAD transmembrane transport ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Component Evidence Code Pubs
    located_in mitochondrial inner membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in mitochondrion HDA PubMed 
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in mitochondrion IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in mitochondrion ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    solute carrier family 25 member 32
    Names
    mitochondrial FAD transporter
    mitochondrial folate transporter/carrier

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_172402.3NP_765990.2  solute carrier family 25 member 32

      See identical proteins and their annotated locations for NP_765990.2

      Status: VALIDATED

      Source sequence(s)
      AK145178, AK167501, BB308144, BB641480
      Consensus CDS
      CCDS27443.1
      UniProtKB/Swiss-Prot
      Q3TCM5, Q8BMG8
      UniProtKB/TrEMBL
      Q8K0B7
      Related
      ENSMUSP00000022908.9, ENSMUST00000022908.10
      Conserved Domains (2) summary
      PTZ00169
      Location:26307
      PTZ00169; ADP/ATP transporter on adenylate translocase; Provisional
      pfam00153
      Location:116213
      Mito_carr; Mitochondrial carrier protein

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000081.7 Reference GRCm39 C57BL/6J

      Range
      38954625..38976213 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036159580.1XP_036015473.1  solute carrier family 25 member 32 isoform X3

      UniProtKB/TrEMBL
      Q3T9D8
      Conserved Domains (1) summary
      pfam00153
      Location:116213
      Mito_carr; Mitochondrial carrier protein
    2. XM_006521385.5XP_006521448.1  solute carrier family 25 member 32 isoform X2

      UniProtKB/TrEMBL
      Q3T9D8
      Conserved Domains (1) summary
      pfam00153
      Location:118212
      Mito_carr; Mitochondrial carrier protein
    3. XM_036159581.1XP_036015474.1  solute carrier family 25 member 32 isoform X4

      UniProtKB/TrEMBL
      Q3T9D8
      Conserved Domains (1) summary
      pfam00153
      Location:23109
      Mito_carr; Mitochondrial carrier protein
    4. XM_036159578.1XP_036015471.1  solute carrier family 25 member 32 isoform X1

      UniProtKB/TrEMBL
      Q8K0B7
      Related
      ENSMUSP00000154227.2, ENSMUST00000227323.2
      Conserved Domains (2) summary
      PTZ00169
      Location:26292
      PTZ00169; ADP/ATP transporter on adenylate translocase; Provisional
      pfam00153
      Location:206294
      Mito_carr; Mitochondrial carrier protein