U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    Rfx8 regulatory factor X8 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 501127, updated on 27-Dec-2024

    Summary

    Official Symbol
    Rfx8provided by RGD
    Official Full Name
    regulatory factor X8provided by RGD
    Primary source
    RGD:1560724
    See related
    EnsemblRapid:ENSRNOG00000058243 AllianceGenome:RGD:1560724
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1560724; RGD1565676
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Orthologous to human RFX8 (regulatory factor X8). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Testes (RPKM 137.5), Lung (RPKM 30.6) and 6 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Rfx8 in Genome Data Viewer
    Location:
    9q22
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 9 NC_086027.1 (49453282..49517123, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 9 NC_051344.1 (41957589..42021432, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 9 NC_005108.4 (46414407..46476076, complement)

    Chromosome 9 - NC_086027.1Genomic Context describing neighboring genes Neighboring gene ring finger protein 149, pseudogene 2 Neighboring gene ring finger protein 149 Neighboring gene cellular repressor of E1A-stimulated genes 2 Neighboring gene uncharacterized LOC134480363 Neighboring gene small nucleolar RNA SNORA17 Neighboring gene uncharacterized LOC108351918 Neighboring gene uncharacterized LOC120094674 Neighboring gene cytochrome c oxidase subunit 6A1, pseudogene 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General protein information

    Preferred Names
    DNA-binding protein RFX8
    Names
    RFX family member 8, lacking RFX DNA binding domain
    RFX gene family member 8, lacking RFX DNA binding domain
    regulatory factor X 8

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086027.1 Reference GRCr8

      Range
      49453282..49517123 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039084547.1XP_038940475.1  DNA-binding protein RFX8 isoform X2

      UniProtKB/TrEMBL
      A0A8I6GDI7
      Related
      ENSRNOP00000110617.1, ENSRNOT00000161743.1
      Conserved Domains (1) summary
      pfam02257
      Location:1983
      RFX_DNA_binding; RFX DNA-binding domain
    2. XM_039084546.1XP_038940474.1  DNA-binding protein RFX8 isoform X1

      UniProtKB/TrEMBL
      A0A0G2K3E1, A0A8I6GDI7
      Related
      ENSRNOP00000085957.2, ENSRNOT00000108584.2
      Conserved Domains (1) summary
      pfam02257
      Location:1990
      RFX_DNA_binding; RFX DNA-binding domain