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    Myt1 myelin transcription factor 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 362291, updated on 3-Dec-2024

    Summary

    Official Symbol
    Myt1provided by RGD
    Official Full Name
    myelin transcription factor 1provided by RGD
    Primary source
    RGD:1304899
    See related
    EnsemblRapid:ENSRNOG00000017346 AllianceGenome:RGD:1304899
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in positive regulation of transcription by RNA polymerase II. Predicted to act upstream of or within several processes, including diaphragm development; regulation of gene expression; and regulation of insulin secretion involved in cellular response to glucose stimulus. Predicted to be located in cytosol and nucleoplasm. Predicted to be active in nucleus. Orthologous to human MYT1 (myelin transcription factor 1). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Restricted expression toward (RPKM 53.3) See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Myt1 in Genome Data Viewer
    Location:
    3q43
    Exon count:
    28
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 3 NC_086021.1 (189263569..189327844)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 3 NC_051338.1 (168890466..168950341)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 3 NC_005102.4 (177281365..177341550)

    Chromosome 3 - NC_086021.1Genomic Context describing neighboring genes Neighboring gene LKAAEAR motif containing 1 Neighboring gene opioid related nociceptin receptor 1 Neighboring gene uncharacterized LOC134486518 Neighboring gene uncharacterized LOC120101836 Neighboring gene protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2 Neighboring gene RNA polymerase III subunit K

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Pathways from PubChem

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    myelin transcription factor 1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001108615.2NP_001102085.2  myelin transcription factor 1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000003
      UniProtKB/TrEMBL
      A0A8I5ZQB6

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086021.1 Reference GRCr8

      Range
      189263569..189327844
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063284249.1XP_063140319.1  myelin transcription factor 1 isoform X2

      UniProtKB/TrEMBL
      A0A8I5ZQB6, A0A8I6GF57
      Related
      ENSRNOP00000087460.1, ENSRNOT00000102710.2
    2. XM_063284251.1XP_063140321.1  myelin transcription factor 1 isoform X4

    3. XM_063284248.1XP_063140318.1  myelin transcription factor 1 isoform X1

      UniProtKB/TrEMBL
      A0A8I5ZQB6
      Related
      ENSRNOP00000100471.1, ENSRNOT00000172969.1
    4. XM_063284252.1XP_063140322.1  myelin transcription factor 1 isoform X4

      UniProtKB/TrEMBL
      A0A8I5ZQB6
      Related
      ENSRNOP00000080274.1, ENSRNOT00000094940.2
    5. XM_063284253.1XP_063140323.1  myelin transcription factor 1 isoform X5

      UniProtKB/TrEMBL
      A6KLW0, D3ZYT5
    6. XM_063284255.1XP_063140325.1  myelin transcription factor 1 isoform X6

    7. XM_063284256.1XP_063140326.1  myelin transcription factor 1 isoform X7

    8. XM_063284257.1XP_063140327.1  myelin transcription factor 1 isoform X8

    9. XM_063284258.1XP_063140328.1  myelin transcription factor 1 isoform X9

    10. XM_063284250.1XP_063140320.1  myelin transcription factor 1 isoform X3

      UniProtKB/TrEMBL
      A0A8I5ZKR6
    11. XM_063284254.1XP_063140324.1  myelin transcription factor 1 isoform X5

      UniProtKB/TrEMBL
      A6KLW0, D3ZYT5