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    Zfp870 zinc finger protein 870 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 362845, updated on 9-Dec-2024

    Summary

    Official Symbol
    Zfp870provided by RGD
    Official Full Name
    zinc finger protein 870provided by RGD
    Primary source
    RGD:1597136
    See related
    EnsemblRapid:ENSRNOG00000030416 AllianceGenome:RGD:1597136
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Zfp709l2
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to act upstream of or within cellular lipid metabolic process. Predicted to be active in nucleus. Orthologous to human ZNF670 (zinc finger protein 670). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Heart (RPKM 60.4), Muscle (RPKM 56.5) and 9 other tissues See more
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    Genomic context

    See Zfp870 in Genome Data Viewer
    Location:
    7q11
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 7 NC_086025.1 (12640653..12654320, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 7 NC_051342.1 (11990146..12003813, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 7 NC_005106.4 (15158673..15172489, complement)

    Chromosome 7 - NC_086025.1Genomic Context describing neighboring genes Neighboring gene ferritin light chain 1 like 5 Neighboring gene zinc finger protein 14-like Neighboring gene zinc finger protein 799 Neighboring gene nuclear transport factor 2 like 1 Neighboring gene cytochrome P450, family 4, subfamily f, polypeptide 1 Neighboring gene cytochrome P450, family 4, subfamily f, polypeptide 6

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within lipid metabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    zinc finger protein 709-like 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001163062.1NP_001156534.1  zinc finger protein 709-like 2

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000007
      UniProtKB/TrEMBL
      F1M9J2
      Related
      ENSRNOP00000045589.3, ENSRNOT00000042638.6
      Conserved Domains (6) summary
      smart00349
      Location:458
      KRAB; krueppel associated box
      COG5048
      Location:355543
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:359379
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:443
      KRAB; KRAB box
      pfam13465
      Location:371394
      zf-H2C2_2; Zinc-finger double domain
      cl19284
      Location:260321
      Ribosomal_L37ae; Ribosomal L37ae protein family

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086025.1 Reference GRCr8

      Range
      12640653..12654320 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)