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    Or5ae2 olfactory receptor family 5 subfamily AE member 2 [ Mus musculus (house mouse) ]

    Gene ID: 258410, updated on 9-Dec-2024

    Summary

    Official Symbol
    Or5ae2provided by MGI
    Official Full Name
    olfactory receptor family 5 subfamily AE member 2provided by MGI
    Primary source
    MGI:MGI:3030125
    See related
    Ensembl:ENSMUSG00000070460 AllianceGenome:MGI:3030125
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Olfr291; MOR254-2
    Summary
    Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]
    Expression
    Low expression observed in reference dataset See more
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    Genomic context

    See Or5ae2 in Genome Data Viewer
    Location:
    7 D3; 7 48.38 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (84502779..84506526)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (84853571..84857318)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_19442 Neighboring gene vomeronasal 2, receptor, pseudogene 62 Neighboring gene predicted pseudogene 6155 Neighboring gene vomeronasal 2, receptor, pseudogene 63 Neighboring gene transformation related protein 63 regulated like, pseudogene 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables odorant binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables olfactory receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables olfactory receptor activity ISA
    Inferred from Sequence Alignment
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in membrane ISA
    Inferred from Sequence Alignment
    more info
    PubMed 

    General protein information

    Preferred Names
    olfactory receptor 291
    Names
    GA_x6K02T2NHDJ-11231385-11230438
    olfactory receptor MOR254-2

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_146415.2NP_666527.1  olfactory receptor 291

      See identical proteins and their annotated locations for NP_666527.1

      Status: VALIDATED

      Source sequence(s)
      AC099599
      Consensus CDS
      CCDS21420.1
      UniProtKB/TrEMBL
      Q496V7, Q7TS12, Q8VF60
      Related
      ENSMUSP00000148266.2, ENSMUST00000211582.2
      Conserved Domains (2) summary
      pfam00001
      Location:43293
      7tm_1; 7 transmembrane receptor (rhodopsin family)
      cl21561
      Location:33308
      7tm_4; Olfactory receptor

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      84502779..84506526
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)