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    Ttc27 tetratricopeptide repeat domain 27 [ Mus musculus (house mouse) ]

    Gene ID: 74196, updated on 9-Dec-2024

    Summary

    Official Symbol
    Ttc27provided by MGI
    Official Full Name
    tetratricopeptide repeat domain 27provided by MGI
    Primary source
    MGI:MGI:1921446
    See related
    Ensembl:ENSMUSG00000024078 AllianceGenome:MGI:1921446
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    2610511O17Rik
    Summary
    Orthologous to human TTC27 (tetratricopeptide repeat domain 27). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in CNS E11.5 (RPKM 5.9), liver E14 (RPKM 4.6) and 26 other tissues See more
    Orthologs
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    Genomic context

    See Ttc27 in Genome Data Viewer
    Location:
    17 E2; 17 45.64 cM
    Exon count:
    21
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (75024730..75170565)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (74717735..74863570)

    Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_43225 Neighboring gene predicted gene, 31645 Neighboring gene baculoviral IAP repeat-containing 6 Neighboring gene STARR-seq mESC enhancer starr_43226 Neighboring gene STARR-positive B cell enhancer ABC_E9965 Neighboring gene STARR-positive B cell enhancer ABC_E3215 Neighboring gene STARR-positive B cell enhancer ABC_E7557 Neighboring gene STARR-seq mESC enhancer starr_43230 Neighboring gene STARR-seq mESC enhancer starr_43231 Neighboring gene predicted gene, 31759 Neighboring gene predicted gene, 31818

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (4) 

    Interactions

    General gene information

    Gene Ontology Provided by MGI

    Component Evidence Code Pubs
    is_active_in cellular_component  

    General protein information

    Preferred Names
    tetratricopeptide repeat protein 27
    Names
    TPR repeat protein 27

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_152817.4NP_690030.3  tetratricopeptide repeat protein 27

      See identical proteins and their annotated locations for NP_690030.3

      Status: VALIDATED

      Source sequence(s)
      AI118251, AK030942, AK049324
      Consensus CDS
      CCDS28972.1
      UniProtKB/Swiss-Prot
      Q3THU0, Q8C7S8, Q8CD92, Q8K1D9
      Related
      ENSMUSP00000024882.7, ENSMUST00000024882.8
      Conserved Domains (2) summary
      sd00006
      Location:531559
      TPR; TPR repeat [structural motif]
      pfam13414
      Location:567629
      TPR_11; TPR repeat

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000083.7 Reference GRCm39 C57BL/6J

      Range
      75024730..75170565
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006525025.5XP_006525088.1  tetratricopeptide repeat protein 27 isoform X1

      UniProtKB/Swiss-Prot
      Q8CD92
      Related
      ENSMUSP00000157097.2, ENSMUST00000234568.2
      Conserved Domains (2) summary
      COG0457
      Location:481635
      TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
      sd00006
      Location:531559
      TPR; TPR repeat [structural motif]
    2. XM_006525027.5XP_006525090.1  tetratricopeptide repeat protein 27 isoform X2

      Conserved Domains (3) summary
      TIGR02521
      Location:152295
      type_IV_pilW; type IV pilus biogenesis/stability protein PilW
      TIGR02917
      Location:39259
      PEP_TPR_lipo; putative PEP-CTERM system TPR-repeat lipoprotein
      sd00006
      Location:158186
      TPR; TPR repeat [structural motif]

    RNA

    1. XR_003952200.1 RNA Sequence

    2. XR_003952201.1 RNA Sequence

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