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    Krtap4-6 keratin associated protein 4-6 [ Mus musculus (house mouse) ]

    Gene ID: 68768, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Krtap4-6provided by MGI
    Official Full Name
    keratin associated protein 4-6provided by MGI
    Primary source
    MGI:MGI:1916018
    See related
    Ensembl:ENSMUSG00000075566 AllianceGenome:MGI:1916018
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    1110054P19Rik
    Summary
    Predicted to be located in cytosol and keratin filament. Orthologous to several human genes including KRTAP4-3 (keratin associated protein 4-3). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See Krtap4-6 in Genome Data Viewer
    Location:
    11 D; 11 63.01 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (99555869..99556786, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (99665043..99665960, complement)

    Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene keratin associated protein 4-24 Neighboring gene STARR-seq mESC enhancer starr_30707 Neighboring gene keratin associated protein 4-25 Neighboring gene glyceraldehyde-3-phosphate dehydrogenase pseudogene Neighboring gene keratin associated protein 4-22

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Molecular evolution of the keratin associated protein gene family in mammals, role in the evolution of mammalian hair. Wu DD, et al. BMC Evol Biol, 2008 Aug 23. PMID 18721477, Free PMC Article
    2. Protein-protein interaction panel using mouse full-length cDNAs. Suzuki H, et al. Genome Res, 2001 Oct. PMID 11591653, Free PMC Article
    3. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
    4. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636
    5. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Shibata K, et al. Genome Res, 2000 Nov. PMID 11076861, Free PMC Article

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    General gene information

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    Markers

    Gene Ontology Provided by MGI

    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in keratin filament IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    keratin associated protein 4-6

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_026834.2 → NP_081110.1  keratin associated protein 4-6

      See identical proteins and their annotated locations for NP_081110.1

      Status: VALIDATED

      Source sequence(s)
      AK004258
      Consensus CDS
      CCDS48914.1
      UniProtKB/TrEMBL
      Q3V4B7
      Related
      ENSMUSP00000098045.3, ENSMUST00000100476.3
      Conserved Domains (2) summary
      pfam01500
      Location:39 → 169
      Keratin_B2; Keratin, high sulfur B2 protein
      pfam13885
      Location:99 → 143
      Keratin_B2_2; Keratin, high sulfur B2 protein

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000077.7 Reference GRCm39 C57BL/6J

      Range
      99555869..99556786 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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