Psmd13 proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Psmd13provided by MGI
Official Full Name: proteasome (prosome, macropain) 26S subunit, non-ATPase, 13provided by MGI
Primary source: MGI:MGI:1345192
See related: Ensembl:ENSMUSG00000025487 AllianceGenome:MGI:1345192
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: S11
Summary: Predicted to enable endopeptidase activity and structural molecule activity. Acts upstream of or within meiosis I. Part of proteasome regulatory particle. Is expressed in diencephalon lateral wall ventricular layer; medulla oblongata alar plate ventricular layer; rest of cerebellum ventricular layer; telencephalon ventricular layer; and trunk mesenchyme. Orthologous to human PSMD13 (proteasome 26S subunit, non-ATPase 13). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Ubiquitous expression in CNS E11.5 (RPKM 64.9), placenta adult (RPKM 48.5) and 28 other tissues See more
Orthologs: human all
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Genomic context

Location:: 7 F5; 7 86.09 cM

Exon count:: 13

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	7	NC_000073.7 (140462307..140478555)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	7	NC_000073.6 (140882394..140898642)

Chromosome 7 - NC_000073.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Endonuclease-mediated (1)

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

Dnaja1 (e-PCR), detects polymorphism
- UniSTS:143408

Cox8b (e-PCR), detects polymorphism
- UniSTS:508564

AU019308 (e-PCR)
- UniSTS:159710

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables endopeptidase activity	ISA Inferred from Sequence Alignment more info	PubMed
enables structural molecule activity	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within meiosis I	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in ubiquitin-dependent protein catabolic process	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in cytosol	IBA Inferred from Biological aspect of Ancestor more info
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info
part_of proteasome accessory complex	IDA Inferred from Direct Assay more info	PubMed
part_of proteasome complex	ISO Inferred from Sequence Orthology more info
part_of proteasome regulatory particle	IDA Inferred from Direct Assay more info	PubMed
part_of proteasome regulatory particle, lid subcomplex	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: 26S proteasome non-ATPase regulatory subunit 13

Names: 26S proteasome regulatory subunit RPN9; 26S proteasome regulatory subunit S11; 26S proteasome regulatory subunit p40.5; 26S proteasome subunit p40.5

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.