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    Cdan1 codanin 1 [ Mus musculus (house mouse) ]

    Gene ID: 68968, updated on 27-Nov-2024

    Summary

    Official Symbol
    Cdan1provided by MGI
    Official Full Name
    codanin 1provided by MGI
    Primary source
    MGI:MGI:1916218
    See related
    Ensembl:ENSMUSG00000027284 AllianceGenome:MGI:1916218
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    CDA1; CDAI; CDA-I; codanin-1; 1500015A01Rik
    Summary
    Predicted to be involved in chromatin organization and import into nucleus. Predicted to act upstream of or within protein localization. Located in endomembrane system and nucleus. Is expressed in several structures, including adipose tissue; central nervous system; eye; genitourinary system; and gut. Human ortholog(s) of this gene implicated in congenital dyserythropoietic anemia and congenital dyserythropoietic anemia type Ia. Orthologous to human CDAN1 (codanin 1). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Ubiquitous expression in thymus adult (RPKM 17.2), testis adult (RPKM 7.4) and 28 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Cdan1 in Genome Data Viewer
    Location:
    2 E5; 2 60.37 cM
    Exon count:
    28
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (120546635..120561998, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (120716154..120731517, complement)

    Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_05511 Neighboring gene synaptosomal-associated protein 23 Neighboring gene CapStarr-seq enhancer MGSCv37_chr2:120435029-120435138 Neighboring gene STARR-seq mESC enhancer starr_05512 Neighboring gene STARR-positive B cell enhancer ABC_E414 Neighboring gene leucine rich repeat containing 57 Neighboring gene HAUS augmin-like complex, subunit 2 Neighboring gene StAR related lipid transfer domain containing 9 Neighboring gene STARR-seq mESC enhancer starr_05514 Neighboring gene tau tubulin kinase 2 Neighboring gene STARR-seq mESC enhancer starr_05516 Neighboring gene STARR-positive B cell enhancer ABC_E3396 Neighboring gene expressed sequence AV039307 Neighboring gene ubiquitin protein ligase E3 component n-recognin 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 
    • Gene trapped (1) 
    • Targeted (4)  1 citation

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Potential readthrough

    Included gene: Ttbk2

    Clone Names

    • MGC144128

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    involved_in chromatin organization IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within chromatin organization ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_positive_effect chromatin organization ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in import into nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    acts_upstream_of_or_within nuclear envelope organization TAS
    Traceable Author Statement
    more info
    PubMed 
    acts_upstream_of_or_within protein localization ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytoplasm ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    located_in endomembrane system IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in endomembrane system ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    codanin-1
    Names
    congenital dyserythropoietic anemia type I
    congenital dyserythropoietic anemia, type I

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_026891.2NP_081167.2  codanin-1

      See identical proteins and their annotated locations for NP_081167.2

      Status: VALIDATED

      Source sequence(s)
      AK034144, AK134300, AL935168, BC117555
      Consensus CDS
      CCDS38212.1
      UniProtKB/Swiss-Prot
      A2AW10, Q149P8, Q3U032, Q8CC12
      UniProtKB/TrEMBL
      Z4YL55
      Related
      ENSMUSP00000106329.2, ENSMUST00000110701.8
      Conserved Domains (2) summary
      pfam15229
      Location:130306
      POM121; POM121 family
      pfam15296
      Location:789904
      Codanin-1_C; Codanin-1 C-terminus

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000068.8 Reference GRCm39 C57BL/6J

      Range
      120546635..120561998 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)