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    Fhip2b FHF complex subunit HOOK interacting protein 2B [ Mus musculus (house mouse) ]

    Gene ID: 239170, updated on 27-Nov-2024

    Summary

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    Official Symbol
    Fhip2bprovided by MGI
    Official Full Name
    FHF complex subunit HOOK interacting protein 2Bprovided by MGI
    Primary source
    MGI:MGI:3036290
    See related
    Ensembl:ENSMUSG00000022095 AllianceGenome:MGI:3036290
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Rai16; Fam160b2; G430067P06Rik
    Summary
    Orthologous to human FHIP2B (FHF complex subunit HOOK interacting protein 2B). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Ubiquitous expression in testis adult (RPKM 22.3), ovary adult (RPKM 22.2) and 28 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Fhip2b in Genome Data Viewer
    Location:
    14 D2; 14 36.32 cM
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 14 NC_000080.7 (70820733..70837309, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 14 NC_000080.6 (70583295..70599835, complement)

    Chromosome 14 - NC_000080.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E8570 Neighboring gene predicted gene, 53866 Neighboring gene nudix hydrolase 18 Neighboring gene CapStarr-seq enhancer MGSCv37_chr14:70999253-70999362 Neighboring gene dematin actin binding protein Neighboring gene STARR-seq mESC enhancer starr_37085 Neighboring gene predicted gene, 38605 Neighboring gene fibroblast growth factor 17

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Retinoic acid induced 16 deficiency exacerbates high-fat diet-induced steatohepatitis in mice. Qian CL, et al. Cell Biochem Funct, 2020 Aug. PMID 32289885
    2. Retinoid acid induced 16 deficiency aggravates colitis and colitis-associated tumorigenesis in mice. Xu YL, et al. Cell Death Dis, 2019 Dec 20. PMID 31862898, Free PMC Article
    3. Majority of cerebrospinal fluid-contacting neurons in the spinal cord of C57Bl/6N mice is present in ectopic position unlike in other studied experimental mice strains and mammalian species. Tonelli Gombalová Z, et al. J Comp Neurol, 2020 Oct 15. PMID 32212159
    4. Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method. Piao Y, et al. Genome Res, 2001 Sep. PMID 11544199, Free PMC Article
    5. Fancd2 in vivo interaction network reveals a non-canonical role in mitochondrial function. Zhang T, et al. Sci Rep, 2017 Apr 5. PMID 28378742, Free PMC Article

    See all (19) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Retinoic acid induced 16 deficiency exacerbates high-fat diet-induced steatohepatitis in mice.
      Title: Retinoic acid induced 16 deficiency exacerbates high-fat diet-induced steatohepatitis in mice.
    2. Retinoid acid induced 16 deficiency aggravates colitis and colitis-associated tumorigenesis in mice.
      Title: Retinoid acid induced 16 deficiency aggravates colitis and colitis-associated tumorigenesis in mice.
    Submit: New GeneRIF Correction

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    FHF complex subunit HOOK-interacting protein 2B
    Names
    family with sequence similarity 160, member B2
    protein FAM160B2
    retinoic acid induced 16
    retinoic acid-induced protein 16

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_194345.1 → NP_919326.1  FHF complex subunit HOOK-interacting protein 2B

      See identical proteins and their annotated locations for NP_919326.1

      Status: VALIDATED

      Source sequence(s)
      AC154563, BC058108, BM942664, BU152183, CD348387, CF170130, CN529793
      Consensus CDS
      CCDS49537.1
      UniProtKB/Swiss-Prot
      Q6PED9, Q80YR2, Q8C1Y2
      Related
      ENSMUSP00000022690.10, ENSMUST00000022690.10
      Conserved Domains (1) summary
      pfam10257
      Location:79 → 477
      RAI16-like; Retinoic acid induced 16-like protein

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000080.7 Reference GRCm39 C57BL/6J

      Range
      70820733..70837309 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036158590.1 → XP_036014483.1  FHF complex subunit HOOK-interacting protein 2B isoform X1

      Conserved Domains (1) summary
      pfam10257
      Location:79 → 442
      RAI16-like; Retinoic acid induced 16-like protein

    2. XM_006518998.4 → XP_006519061.1  FHF complex subunit HOOK-interacting protein 2B isoform X2

      Conserved Domains (1) summary
      pfam10257
      Location:10 → 387
      RAI16-like; Retinoic acid induced 16-like protein

    3. XM_017316016.3 → XP_017171505.1  FHF complex subunit HOOK-interacting protein 2B isoform X3

      Conserved Domains (1) summary
      pfam10257
      Location:3 → 186
      RAI16-like; Retinoic acid induced 16-like protein

    4. XM_036158591.1 → XP_036014484.1  FHF complex subunit HOOK-interacting protein 2B isoform X3

      Conserved Domains (1) summary
      pfam10257
      Location:3 → 186
      RAI16-like; Retinoic acid induced 16-like protein
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q80YR2.2 GenPept UniProtKB/Swiss-Prot:Q80YR2

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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