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    Prcc papillary renal cell carcinoma (translocation-associated) [ Mus musculus (house mouse) ]

    Gene ID: 94315, updated on 9-Dec-2024

    Summary

    Official Symbol
    Prccprovided by MGI
    Official Full Name
    papillary renal cell carcinoma (translocation-associated)provided by MGI
    Primary source
    MGI:MGI:2137738
    See related
    Ensembl:ENSMUSG00000004895 AllianceGenome:MGI:2137738
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Summary
    Predicted to be involved in regulation of cell cycle. Predicted to be located in nuclear speck. Predicted to be active in nucleus. Is expressed in several structures, including brain; genitourinary system; liver; lung; and spleen. Human ortholog(s) of this gene implicated in papillary renal cell carcinoma. Orthologous to human PRCC (proline rich mitotic checkpoint control factor). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in CNS E11.5 (RPKM 21.0), CNS E14 (RPKM 18.7) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Prcc in Genome Data Viewer
    Location:
    3 F1; 3 38.78 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (87766210..87792869, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (87858903..87885562, complement)

    Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 32470 Neighboring gene CapStarr-seq enhancer MGSCv37_chr3:87650795-87651072 Neighboring gene SH2 domain containing 2A Neighboring gene CapStarr-seq enhancer MGSCv37_chr3:87689595-87689778 Neighboring gene STARR-seq mESC enhancer starr_08164 Neighboring gene STARR-seq mESC enhancer starr_08165 Neighboring gene heparin binding growth factor Neighboring gene STARR-positive B cell enhancer ABC_E10190 Neighboring gene mitochondrial ribosomal protein L24 Neighboring gene methyltransferase like 25B

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (1) 

    General gene information

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    involved_in regulation of cell cycle ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in nuclear speck ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_033573.2NP_291051.1  proline-rich protein PRCC

      See identical proteins and their annotated locations for NP_291051.1

      Status: VALIDATED

      Source sequence(s)
      BC052072
      Consensus CDS
      CCDS17456.1
      UniProtKB/TrEMBL
      Q05CA9, Q9EQC8
      Related
      ENSMUSP00000005015.9, ENSMUST00000005015.10
      Conserved Domains (1) summary
      pfam10253
      Location:366491
      PRCC; Mitotic checkpoint regulator, MAD2B-interacting

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000069.7 Reference GRCm39 C57BL/6J

      Range
      87766210..87792869 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)