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    Capns2 calpain, small subunit 2 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 679870, updated on 9-Dec-2024

    Summary

    Official Symbol
    Capns2provided by RGD
    Official Full Name
    calpain, small subunit 2provided by RGD
    Primary source
    RGD:1583620
    See related
    AllianceGenome:RGD:1583620
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable calcium-dependent cysteine-type endopeptidase activity. Orthologous to human CAPNS2 (calpain small subunit 2). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See Capns2 in Genome Data Viewer
    Location:
    19p11
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 19 NC_086037.1 (30277324..30278266, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 19 NC_051354.1 (14104334..14105276, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 19 NC_005118.4 (15485258..15486200, complement)

    Chromosome 19 - NC_086037.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134483613 Neighboring gene carboxylesterase 1A Neighboring gene solute carrier family 6 member 2 Neighboring gene lysophosphatidylcholine acyltransferase 2 Neighboring gene matrix metallopeptidase 2 Neighboring gene uncharacterized LOC120098544

    Genomic regions, transcripts, and products

    General protein information

    Preferred Names
    calpain small subunit 2
    NP_001102850.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001109380.1NP_001102850.1  calpain small subunit 2

      See identical proteins and their annotated locations for NP_001102850.1

      Status: PROVISIONAL

      Source sequence(s)
      CH474037
      UniProtKB/TrEMBL
      A6KD57
      Conserved Domains (2) summary
      pfam13499
      Location:154209
      EF-hand_7; EF-hand domain pair
      cl08302
      Location:123168
      EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086037.1 Reference GRCr8

      Range
      30277324..30278266 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)