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    Creg2 cellular repressor of E1A-stimulated genes 2 [ Mus musculus (house mouse) ]

    Gene ID: 263764, updated on 9-Dec-2024

    Summary

    Official Symbol
    Creg2provided by MGI
    Official Full Name
    cellular repressor of E1A-stimulated genes 2provided by MGI
    Primary source
    MGI:MGI:1928333
    See related
    Ensembl:ENSMUSG00000050967 AllianceGenome:MGI:1928333
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    A830098L22Rik
    Summary
    Located in Golgi apparatus and endoplasmic reticulum. Is expressed in lung epithelium; medulla oblongata; medulla oblongata basal plate mantle layer; and nasal cavity respiratory epithelium. Orthologous to human CREG2 (cellular repressor of E1A stimulated genes 2). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in cortex adult (RPKM 9.6), frontal lobe adult (RPKM 8.0) and 6 other tissues See more
    Orthologs
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    Genomic context

    See Creg2 in Genome Data Viewer
    Location:
    1 B; 1 18.37 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (39657574..39690350, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (39618406..39652052, complement)

    Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene ring finger protein 149 Neighboring gene predicted gene, 23722 Neighboring gene predicted gene, 51620 Neighboring gene predicted gene 5100 Neighboring gene RIKEN cDNA D930019O06 Neighboring gene STARR-seq mESC enhancer starr_00725 Neighboring gene STARR-seq mESC enhancer starr_00727 Neighboring gene regulatory factor X 8

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
     
    Component Evidence Code Pubs
    located_in Golgi apparatus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in endoplasmic reticulum IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in extracellular space IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_170597.4NP_733485.1  protein CREG2 precursor

      See identical proteins and their annotated locations for NP_733485.1

      Status: VALIDATED

      Source sequence(s)
      AC119809, AK044192
      Consensus CDS
      CCDS14908.1
      UniProtKB/Swiss-Prot
      Q14AL7, Q8BGC9, Q8BL64, Q8BX89, Q8K049
      UniProtKB/TrEMBL
      Q3UY95, Q3UYF8
      Related
      ENSMUSP00000052871.5, ENSMUST00000053355.6
      Conserved Domains (1) summary
      pfam13883
      Location:116282
      Pyrid_oxidase_2; Pyridoxamine 5'-phosphate oxidase

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000067.7 Reference GRCm39 C57BL/6J

      Range
      39657574..39690350 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)