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    Spin4 spindlin family, member 4 [ Mus musculus (house mouse) ]

    Gene ID: 270624, updated on 9-Dec-2024

    Summary

    Official Symbol
    Spin4provided by MGI
    Official Full Name
    spindlin family, member 4provided by MGI
    Primary source
    MGI:MGI:2444925
    See related
    Ensembl:ENSMUSG00000071722 AllianceGenome:MGI:2444925
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    9630042H07Rik
    Summary
    Predicted to enable methylated histone binding activity. Involved in positive regulation of canonical Wnt signaling pathway. Predicted to be located in chromatin; cytoplasm; and nucleus. Predicted to be active in cytosol and nucleoplasm. Orthologous to human SPIN4 (spindlin family member 4). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    NEW
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    Genomic context

    See Spin4 in Genome Data Viewer
    Location:
    X C3; X 41.83 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) X NC_000086.8 (94066113..94070288, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) X NC_000086.7 (95022507..95026682, complement)

    Chromosome X - NC_000086.8Genomic Context describing neighboring genes Neighboring gene predicted gene, 54087 Neighboring gene STARR-positive B cell enhancer mm9_chrX:92123270-92123571 Neighboring gene STARR-positive B cell enhancer mm9_chrX:92127397-92127698 Neighboring gene STARR-positive B cell enhancer mm9_chrX:92128436-92128737 Neighboring gene STARR-positive B cell enhancer mm9_chrX:92128771-92129071 Neighboring gene STARR-positive B cell enhancer mm9_chrX:92130222-92130523 Neighboring gene STARR-positive B cell enhancer mm9_chrX:92131186-92131487 Neighboring gene STARR-positive B cell enhancer mm9_chrX:92132186-92132487 Neighboring gene STARR-positive B cell enhancer mm9_chrX:92136714-92137015 Neighboring gene STARR-positive B cell enhancer mm9_chrX:92137671-92137972 Neighboring gene STARR-positive B cell enhancer mm9_chrX:92138811-92139112 Neighboring gene STARR-positive B cell enhancer mm9_chrX:92138430-92138731 Neighboring gene STARR-positive B cell enhancer mm9_chrX:92139803-92140104 Neighboring gene STARR-positive B cell enhancer mm9_chrX:92142094-92142394 Neighboring gene STARR-positive B cell enhancer mm9_chrX:92142861-92143162 Neighboring gene STARR-positive B cell enhancer mm9_chrX:92145272-92145572 Neighboring gene STARR-positive B cell enhancer mm9_chrX:92146544-92146845 Neighboring gene STARR-positive B cell enhancer mm9_chrX:92146901-92147202 Neighboring gene STARR-positive B cell enhancer mm9_chrX:92147877-92148177 Neighboring gene STARR-positive B cell enhancer mm9_chrX:92150970-92151271 Neighboring gene STARR-positive B cell enhancer mm9_chrX:92152746-92153047 Neighboring gene STARR-positive B cell enhancer mm9_chrX:92152080-92152381 Neighboring gene STARR-positive B cell enhancer mm9_chrX:92153049-92153349 Neighboring gene STARR-positive B cell enhancer mm9_chrX:92156826-92157127 Neighboring gene STARR-positive B cell enhancer mm9_chrX:92157184-92157485 Neighboring gene STARR-positive B cell enhancer mm9_chrX:92158408-92158708 Neighboring gene STARR-positive B cell enhancer mm9_chrX:92159204-92159505 Neighboring gene STARR-positive B cell enhancer mm9_chrX:92159763-92160064 Neighboring gene STARR-positive B cell enhancer mm9_chrX:92160302-92160603 Neighboring gene STARR-positive B cell enhancer mm9_chrX:92160986-92161287 Neighboring gene STARR-positive B cell enhancer mm9_chrX:92162208-92162509 Neighboring gene STARR-positive B cell enhancer mm9_chrX:92162970-92163271 Neighboring gene STARR-positive B cell enhancer mm9_chrX:92165507-92165808 Neighboring gene STARR-positive B cell enhancer mm9_chrX:92167787-92168088 Neighboring gene STARR-positive B cell enhancer mm9_chrX:92173712-92174012 Neighboring gene STARR-seq mESC enhancer starr_47564 Neighboring gene germ cell-less homolog 1 pseudogene Neighboring gene CDC42 guanine nucleotide exchange factor 9 Neighboring gene STARR-seq mESC enhancer starr_47565 Neighboring gene STARR-seq mESC enhancer starr_47566 Neighboring gene adenylate kinase 1 pseudogene

    Genomic regions, transcripts, and products

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables methylated histone binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables methylated histone binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables methylated histone binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Component Evidence Code Pubs
    located_in chromatin ISO
    Inferred from Sequence Orthology
    more info
     
    located_in chromatin ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytoplasm ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in nucleoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
     

    General protein information

    Preferred Names
    spindlin-4
    Names
    novel Spin/Ssty repeat containing protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_178753.4NP_848868.1  spindlin-4

      See identical proteins and their annotated locations for NP_848868.1

      Status: VALIDATED

      Source sequence(s)
      AK036158, AK147852, BB059605
      Consensus CDS
      CCDS30282.1
      UniProtKB/Swiss-Prot
      Q8BXD0, Q8K1L2
      Related
      ENSMUSP00000094095.4, ENSMUST00000096367.5
      Conserved Domains (1) summary
      pfam02513
      Location:4189
      Spin-Ssty; Spin/Ssty Family

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000086.8 Reference GRCm39 C57BL/6J

      Range
      94066113..94070288 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)