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    Lsmem2 leucine-rich single-pass membrane protein 2 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 689621, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Lsmem2provided by RGD
    Official Full Name
    leucine-rich single-pass membrane protein 2provided by RGD
    Primary source
    RGD:1589957
    See related
    EnsemblRapid:ENSRNOG00000052634 AllianceGenome:RGD:1589957
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be located in membrane. Orthologous to human LSMEM2 (leucine rich single-pass membrane protein 2). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Muscle (RPKM 57.6), Heart (RPKM 51.2) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Lsmem2 in Genome Data Viewer
    Location:
    8q32
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 8 NC_086026.1 (117144498..117149300, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 8 NC_051343.1 (108265855..108270656, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (116348406..116353092, complement)

    Chromosome 8 - NC_086026.1Genomic Context describing neighboring genes Neighboring gene hyaluronidase 2 Neighboring gene hyaluronidase 1 Neighboring gene N(alpha)-acetyltransferase 80, NatH catalytic subunit Neighboring gene hyaluronidase 3 Neighboring gene interferon-related developmental regulator 2 Neighboring gene semaphorin 3B Neighboring gene uncharacterized LOC120094260 Neighboring gene G protein subunit alpha i2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    leucine-rich single-pass membrane protein 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001430399.1 → NP_001417328.1  leucine-rich single-pass membrane protein 2

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000008
      UniProtKB/TrEMBL
      A0A8I6A425, A6I2Z0

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086026.1 Reference GRCr8

      Range
      117144498..117149300 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001071401.5 → XP_001071401.1  leucine-rich single-pass membrane protein 2 isoform X2

      Related
      ENSRNOP00000108614.1, ENSRNOT00000157156.1
      Conserved Domains (1) summary
      pfam15833
      Location:1 → 148
      DUF4714; Domain of unknown function (DUF4714)

    2. XM_039082622.1 → XP_038938550.1  leucine-rich single-pass membrane protein 2 isoform X1

      UniProtKB/TrEMBL
      A0A0G2KAD9
      Related
      ENSRNOP00000075362.3, ENSRNOT00000087306.3
      Conserved Domains (1) summary
      pfam15833
      Location:72 → 217
      DUF4714; Domain of unknown function (DUF4714)
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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    Chemical Information
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    Research Materials