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    Zfp410 zinc finger protein 410 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 314310, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Zfp410provided by RGD
    Official Full Name
    zinc finger protein 410provided by RGD
    Primary source
    RGD:1305636
    See related
    EnsemblRapid:ENSRNOG00000010985 AllianceGenome:RGD:1305636
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Znf410
    Summary
    Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in negative regulation of gene expression and positive regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Orthologous to human ZNF410 (zinc finger protein 410). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Thymus (RPKM 142.0), Kidney (RPKM 89.9) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Zfp410 in Genome Data Viewer
    Location:
    6q31
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 6 NC_086024.1 (109695223..109721369)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 6 NC_051341.1 (103963265..103990252)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 6 NC_005105.4 (108031747..108058836)

    Chromosome 6 - NC_086024.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134479232 Neighboring gene prostaglandin reductase 2 Neighboring gene FAM161 centrosomal protein B Neighboring gene coenzyme Q6 monooxygenase Neighboring gene ectonucleoside triphosphate diphosphohydrolase 5 Neighboring gene basal body orientation factor 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables sequence-specific double-stranded DNA binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    Process Evidence Code Pubs
    involved_in negative regulation of gene expression ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in positive regulation of transcription by RNA polymerase II ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    zinc finger protein 410

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001108042.3 → NP_001101512.1  zinc finger protein 410

      See identical proteins and their annotated locations for NP_001101512.1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000006
      UniProtKB/TrEMBL
      A0A8I6A1H7, A6JDU7, B4F792, F7FMS9
      Conserved Domains (3) summary
      COG5048
      Location:228 → 368
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:281 → 303
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13465
      Location:325 → 350
      zf-H2C2_2; Zinc-finger double domain

    2. NM_001433978.1 → NP_001420907.1  zinc finger protein 410

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000006
      UniProtKB/TrEMBL
      A0A8I6A1H7, A6JDU7, B4F792, F7FMS9

    3. NM_001433979.1 → NP_001420908.1  zinc finger protein 410

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000006
      UniProtKB/TrEMBL
      A0A8I6A1H7, A6JDU7, B4F792, F7FMS9

    RNA

    1. NR_197622.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000006

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086024.1 Reference GRCr8

      Range
      109695223..109721369
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063261938.1 → XP_063118008.1  zinc finger protein 410 isoform X1

      UniProtKB/TrEMBL
      A0A8I6A1H7

    2. XM_063261939.1 → XP_063118009.1  zinc finger protein 410 isoform X2

    3. XM_063261937.1 → XP_063118007.1  zinc finger protein 410 isoform X1

      UniProtKB/TrEMBL
      A0A8I6A1H7

    4. XM_006240338.3 → XP_006240400.1  zinc finger protein 410 isoform X2

      Related
      ENSRNOP00000014738.5, ENSRNOT00000014738.7
      Conserved Domains (3) summary
      COG5048
      Location:228 → 368
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:281 → 303
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13465
      Location:325 → 350
      zf-H2C2_2; Zinc-finger double domain

    5. XM_063261936.1 → XP_063118006.1  zinc finger protein 410 isoform X1

      UniProtKB/TrEMBL
      A0A8I6A1H7

    RNA

    1. XR_005505524.2 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version

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