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    Lrrc73 leucine rich repeat containing 73 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 501101, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Lrrc73provided by RGD
    Official Full Name
    leucine rich repeat containing 73provided by RGD
    Primary source
    RGD:1561390
    See related
    EnsemblRapid:ENSRNOG00000039856 AllianceGenome:RGD:1561390
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    nod3l
    Summary
    Orthologous to human LRRC73 (leucine rich repeat containing 73). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Brain (RPKM 18.6), Testes (RPKM 17.0) and 7 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Lrrc73 in Genome Data Viewer
    Location:
    9q12
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 9 NC_086027.1 (22223735..22227867, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 9 NC_051344.1 (14726157..14730144, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 9 NC_005108.4 (17111176..17115249, complement)

    Chromosome 9 - NC_086027.1Genomic Context describing neighboring genes Neighboring gene U6 spliceosomal RNA Neighboring gene tight junction associated protein 1 Neighboring gene Yip1 domain family, member 3 Neighboring gene RNA polymerase I and III subunit C Neighboring gene exportin 5

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Night/day changes in pineal expression of >600 genes: central role of adrenergic/cAMP signaling. Bailey MJ, et al. J Biol Chem, 2009 Mar 20. PMID 19103603, Free PMC Article
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    General protein information

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    Preferred Names
    leucine-rich repeat-containing protein 73
    Names
    NOD3-like protein
    uncharacterized protein C6orf154 homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001024360.2 → NP_001019531.1  leucine-rich repeat-containing protein 73

      See identical proteins and their annotated locations for NP_001019531.1

      Status: PROVISIONAL

      Source sequence(s)
      BC128712
      UniProtKB/Swiss-Prot
      A1A5L6, Q587K4
      UniProtKB/TrEMBL
      A6JIS4
      Related
      ENSRNOP00000057899.2, ENSRNOT00000061185.4
      Conserved Domains (2) summary
      sd00033
      Location:58 → 86
      LRR_RI; leucine-rich repeat [structural motif]
      cl39015
      Location:5 → 255
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086027.1 Reference GRCr8

      Range
      22223735..22227867 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_008766878.4 → XP_008765100.1  leucine-rich repeat-containing protein 73 isoform X1

      Conserved Domains (1) summary
      cl39015
      Location:11 → 213
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...

    2. XM_039084064.1 → XP_038939992.1  leucine-rich repeat-containing protein 73 isoform X2

      Conserved Domains (1) summary
      cl39015
      Location:19 → 132
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...

    3. XM_063267579.1 → XP_063123649.1  leucine-rich repeat-containing protein 73 isoform X3

    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q587K4.1 GenPept UniProtKB/Swiss-Prot:Q587K4

    Gene LinkOut

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