Pop4 POP4 homolog, ribonuclease P/MRP subunit [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Pop4provided by RGD
Official Full Name: POP4 homolog, ribonuclease P/MRP subunitprovided by RGD
Primary source: RGD:1305955
See related: EnsemblRapid:ENSRNOG00000027646 AllianceGenome:RGD:1305955
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to enable ribonuclease P RNA binding activity. Predicted to contribute to ribonuclease P activity. Predicted to be involved in rRNA processing and tRNA 5'-leader removal. Predicted to be located in nucleolus and nucleoplasm. Predicted to be part of multimeric ribonuclease P complex and ribonuclease MRP complex. Orthologous to human POP4 (POP4 homolog, ribonuclease P/MRP subunit). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Thymus (RPKM 194.9), Brain (RPKM 139.8) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 1q21

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	1	NC_086019.1 (100096722..100105056, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	1	NC_051336.1 (90960026..90968360, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	1	NC_005100.4 (94661127..94669461, complement)

Chromosome 1 - NC_086019.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Markers

RH129653 (e-PCR)
- UniSTS:212950

RH127886 (e-PCR)
- UniSTS:211196

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables ribonuclease P RNA binding	IBA Inferred from Biological aspect of Ancestor more info
enables ribonuclease P RNA binding	IEA Inferred from Electronic Annotation more info
enables ribonuclease P RNA binding	ISO Inferred from Sequence Orthology more info
enables ribonuclease P RNA binding	ISS Inferred from Sequence or Structural Similarity more info
contributes_to ribonuclease P activity	ISO Inferred from Sequence Orthology more info
contributes_to ribonuclease P activity	ISS Inferred from Sequence or Structural Similarity more info

Process	Evidence Code	Pubs
involved_in biological_process	ND No biological Data available more info
involved_in rRNA processing	IBA Inferred from Biological aspect of Ancestor more info
involved_in tRNA 5'-leader removal	IEA Inferred from Electronic Annotation more info
involved_in tRNA 5'-leader removal	ISO Inferred from Sequence Orthology more info
involved_in tRNA 5'-leader removal	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
part_of multimeric ribonuclease P complex	ISO Inferred from Sequence Orthology more info
part_of multimeric ribonuclease P complex	ISS Inferred from Sequence or Structural Similarity more info
located_in nucleolus	IEA Inferred from Electronic Annotation more info
located_in nucleolus	ISO Inferred from Sequence Orthology more info
located_in nucleoplasm	ISO Inferred from Sequence Orthology more info
part_of ribonuclease MRP complex	IBA Inferred from Biological aspect of Ancestor more info
part_of ribonuclease MRP complex	IEA Inferred from Electronic Annotation more info
part_of ribonuclease P complex	IBA Inferred from Biological aspect of Ancestor more info
part_of ribonuclease P complex	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: ribonuclease P protein subunit p29

Names: POP4 (processing of precursor , S. cerevisiae) homolog; processing of precursor 4, ribonuclease P/MRP subunit

NP_001009642.1

EC 3.1.26.5

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.