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    Hs3st4 heparan sulfate (glucosamine) 3-O-sulfotransferase 4 [ Mus musculus (house mouse) ]

    Gene ID: 628779, updated on 9-Dec-2024

    Summary

    Official Symbol
    Hs3st4provided by MGI
    Official Full Name
    heparan sulfate (glucosamine) 3-O-sulfotransferase 4provided by MGI
    Primary source
    MGI:MGI:1333792
    See related
    Ensembl:ENSMUSG00000078591 AllianceGenome:MGI:1333792
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gm6915
    Summary
    Predicted to enable [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity. Involved in heparan sulfate proteoglycan biosynthetic process. Is expressed in ear; integumental system; and nervous system. Orthologous to human HS3ST4 (heparan sulfate-glucosamine 3-sulfotransferase 4). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in cortex adult (RPKM 5.4), CNS E18 (RPKM 4.8) and 5 other tissues See more
    Orthologs
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    Genomic context

    See Hs3st4 in Genome Data Viewer
    Location:
    7 F3; 7 67.56 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (123581586..123998212)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (123982366..124398989)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 30335 Neighboring gene predicted gene, 23788 Neighboring gene predicted gene, 26974 Neighboring gene VISTA enhancer mm687 Neighboring gene STARR-seq mESC enhancer starr_20101 Neighboring gene RIKEN cDNA 4930551E15 gene Neighboring gene predicted gene, 25759 Neighboring gene STARR-seq mESC enhancer starr_20103 Neighboring gene STARR-seq mESC enhancer starr_20104 Neighboring gene STARR-seq mESC enhancer starr_20107 Neighboring gene predicted gene, 23168 Neighboring gene predicted gene, 57516

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Pathways from PubChem

    General gene information

    Gene Ontology Provided by MGI

    Component Evidence Code Pubs
    is_active_in cellular_component  

    General protein information

    Preferred Names
    heparan sulfate glucosamine 3-O-sulfotransferase 4
    NP_001239001.1
    XP_006508167.1
    XP_030098720.1
    XP_030098722.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001252072.2NP_001239001.1  heparan sulfate glucosamine 3-O-sulfotransferase 4

      Status: VALIDATED

      Source sequence(s)
      AC126278, AC151718, BQ177219, CJ154897
      Consensus CDS
      CCDS57584.1
      UniProtKB/TrEMBL
      D3YVV6
      Related
      ENSMUSP00000102045.2, ENSMUST00000106437.2
      Conserved Domains (1) summary
      pfam00685
      Location:190427
      Sulfotransfer_1; Sulfotransferase domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      123581586..123998212
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030242860.2XP_030098720.1  heparan sulfate glucosamine 3-O-sulfotransferase 4 isoform X1

      Conserved Domains (1) summary
      cl21551
      Location:190238
      Sulfotransfer_3; Sulfotransferase family
    2. XM_006508104.5XP_006508167.1  heparan sulfate glucosamine 3-O-sulfotransferase 4 isoform X2

      Conserved Domains (1) summary
      pfam00685
      Location:32204
      Sulfotransfer_1; Sulfotransferase domain
    3. XM_030242862.1XP_030098722.1  heparan sulfate glucosamine 3-O-sulfotransferase 4 isoform X3

      Conserved Domains (1) summary
      pfam00685
      Location:22194
      Sulfotransfer_1; Sulfotransferase domain

    RNA

    1. XR_003946536.2 RNA Sequence

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